Tag: Clinical Trials

The Drug Propecia and Hair Loss

The drug propecia is a prescription hair loss medication designed mainly for men with mild to moderate hair loss. The effects of hair loss and propecia were studied in several clinical trials, and propecia was found to be better than a placebo.

The men in the studies, aged between 18 and 41, took propecia daily for a year. Some men took a placebo. Of the men who took the propecia, 86% either did not suffer further hair loss, or actually increased the amount of hair in the affected areas. Only 14% of men had continued hair loss.

The drug propecia has been found to be ineffective for women. This, combined with the potential danger of abnormalities to a male fetus, means that propecia is not prescribed for female pattern hair loss. Propecia has not been studied in older men, or men with complete baldness, and it has not been proved to work with a receding hairline. Propecia is not suitable for children, no doubt due to its negative effect on developing male genitals.

Generally, propecia is a very safe drug for hair loss. Most men taking it did not have any side effects, though some reported:

* erection difficulties

* reduced amount of semen

* less sexual desire

These were not permanent changes, and when those affected stopped taking propecia, their symptoms disappeared. Some men who reported these side effects were also able to continue taking propecia without the side effects continuing. The report I saw did not say whether the side effects just stopped, or if other treatment was undertaken to counteract them.

The drug propecia has only been studied on men for up to two years, and these men had no problems taking it for this period. However, based on research over a period of 32 years on men who are deficient on the enzyme that propecia suppresses, 5-alpha reductase, the mechanism by which propecia works seems to be quite safe for long term use.

Disadvantages of Taking Propecia

Propecia is not a cure for hair loss. Propecia works by interrupting the conversion process of testosterone to its metabolite, dihydrotestosterone (DHT for short). It does this by effecting the enzyme catalyst, 5-alpha reductase, that is involved in the conversion process.

In male pattern hair loss, there is an excess of DHT in the part of the scalp where hair loss occurs. So, by reducing the amounts of DHT in the scalp, propecia effectively works to prevent new hair loss, and allows hair to regrow. However, to continue the benefits of propecia, you’ll need to take it for the rest of your life. Once you stop taking propecia, the DHT levels will rise again in the scalp, and hair loss will return to pre-propecia levels.

The Drug Propecia and Pregnancy

Women should be very careful not to handle propecia if they are pregnant, as it can affect the development of the sex organs in a male fetus. So, it would be wise not to touch any open packets, or broken tablets. If you must, use a glove. Unbroken tablets are safety coated, so the active ingredient of propecia, which is the potential problem, is not present on the outside of the tablet.

For men taking propecia, if your wife is pregnant, there is no risk to her unless she is exposed to the active ingredient from a broken tablet. She, or the baby, won’t be harmed when her partner is taking it.

However, given that in some men propecia affects the amount of semen produced, if you are trying to conceive this may pose a problem. This side effect does not affect all, or most, men. But check with your doctor if you think this may be a concern.

Is Saw Palmetto Used For Male Pattern Baldness?

Many nowadays prefer a natural hair loss remedy rather than treat their hair loss with drugs and medication. If you are looking for a natural hair loss remedy for male pattern baldness, you can try saw palmetto.

Saw palmetto is a particular type of fruit that has been shown to help in hair loss according to some studies.
Having some information about saw palmetto, its use and its benefits can help you decide if this natural hair loss remedy is the type of treatment that you are seeking for.

Saw palmetto is a red fruit that grows in warmer climates throughout the world. It is most often seen in South Eastern regions of the United States. Studies into the use of saw palmetto was first done for research on prostate health. However, it was also noticed during the clinical trials that this popular fruit have positive benefits to those with male pattern baldness.

Male pattern baldness is a hereditary condition that afflicts more men than women. Hair loss in male pattern baldness is characterized by a receding hairline and that continues in a horseshoe pattern. Hair on the sides and back of the head are mostly unaffected. The exact reason for male pattern baldness is still not very clear.

Some studies suggest that excessive conversion of testosterone to another hormone called dihydrotestosterone (DHT) may be an underlying cause. In the studies for prostate health, saw palmetto was shown to block the production of DHT in men suffering from enlargement of the prostate.

So how much saw palmetto should you eat for your hair loss? Unverified sources say that if you are eating the fruit, then one per day would in most instances be effective with treating your hair loss. However, if you are taking an extract, then a dosage of three hundred and twenty milligrams per day is recommended. Supplements containing nutrients of saw palmetto are also available to help with hair growth.

One of the advantages of taking saw palmetto is that there are no known side effects. This is obviously better than taking synthetic drugs or medication that may have potential adverse results. In fact, these side effects include fast heart rate, headaches, impotence, and decreased libido.

Saw palmetto should preferably be taken with other foods or substances. Otherwise, you may end up with a headache or stomachache. In addition, if you observed that you are getting allergic reactions, you should stop consuming saw palmetto immediately.

In addition, if you are female and pregnant, then you should not use saw palmetto without medical supervision.

Is Saw Palmetto used for Male Pattern Baldness? Currently, there is no known cure for male pattern baldness. Both conventional and natural treatments can help control the hair loss as long as one maintains the treatment. However, once the treatment is discontinued, there is the chance of recurrence.

Saw palmetto may be the answer to providing your body with the necessary balance of the hormones and enzymes beneficial for combating hair loss. Do research more into this option if you are looking for a natural hair loss remedy for mild to moderate male pattern baldness.

Incisions and Scaring

Surgery leaves scars. While most breast augmentation incisions do heal well, a rate of 6-7% of unfavorable scaring has been reported for primary augmentation patients in FDA clinical trials.

The extent of the scaring can be determined by many factors. These include the patients ethnicity, smoking, tissue quality, suture material, wound tension, tissue trauma from surgery and the individuals tendency toward favorable wound healing.

The type of incision also affects the amount and visibility of scaring. The type of planned incision should be discussed with your surgeon prior to the procedure.

The most common incision for silicone gel implants is the inframammary incision. This affords maximum access for precise dissection and placement of an implant. The incision is placed below the breast in the infra-mammary fold. This incision can leave slightly more visible scars in smaller breasts which dont drape over the IMF.

Transaxillary incisions are placed in the armpit. This allows the implants to be placed without visible scars on the breasts. Its also more likely to consistently achieve symmetry of the inferior implant position.

Periareolar incisions are placed along the areolar border. The incision is usually placed around the inferior half of the areolas circumference. Because of the incision length required, silicone gel implants can be hard to place using this method. These scars are often less visible in women with lighter areolar pigment since they occur on the edge of the areola. There is a higher chance of capsular contracture with this incision.