Tag: stem cells

How to Find Current Research on Congestive Heart Failure

Medical research is a never ending fount of information, and its sources are vast. Unfortunately, it may be very difficult for a layman not associated with the medical field to find up to date information pertaining to his disease and treatment options. While doctors are constantly attending conferences as part of their continuing education curriculum, the average Joe is left to sort through a variety of sources in an attempt to find information that is not obsolete. The best choice for this patient is to continue his research in one of the many scientific research journals published.

While a specific journal pertaining solely to the topic of congestive heart failure may not be available, there are a seemingly infinite number of research journals being published that pertain to medical issues (there are research journals published for any field in which there is someone doing research). These are available in both a virtual format or in a hard copy. If a research source is found that a patient particularly favors they can purchase a subscription, which will allow them to receive new issues of the journal as they are released. When researching a specific topic or disease purchasing a subscription to just one source may not be the action of choice. Often a variety of articles pertaining to a specific topic can be found in multiple journals, and it is often more beneficial to read more than one. Libraries will often carry a subscription to several periodicals, and many will publish an edition over the internet. A portion of the journals that can be found online allow readers full access without a subscription.

Scientific journals publish cutting edge research, giving the average person a chance to read about advances in medicine and technology that are occurring in every field. Is was a scientific journal that first published the information about stem cell research that sparked a controversy across the nation, and these same stem cells are now considered one of the best chances for providing long term relief for patients suffering from heart failure. Through scientific journals the reader is taken through laboratories around the world and exposed to ideas and theories of some of the planet’s greatest minds.

When searching for a research journal from which to learn it is important to ascertain that it is, in fact, a reputable source. Research journals publish both theory and fact, and it is essential that the two be differentiated. A publication with a reputation of publishing theories as facts should be avoided. If a patient is unfamiliar with the world of science it would probably be helpful for them to seek the aid of their physician in finding a factual source of information which publishes only peer reviewed articles and up to date research.

It is important to remember that the articles written in scientific journals are written by health professionals for health professionals, and may be very difficult for a person uneducated in anatomy and medical terminology to understand; however, when armed with a dictionary and a physician to consult with scientific journals are an endless source of information.

Hair Cloning Research for Hair Transplant Procedures

The future of hair transplant procedures is in the laboratories at this very time. Scientists are working together to find a way to make the surgery work for more people. They also want to see it work better for the types of people who have hair transplants today. One area of research is hair cloning.

Hair cloning promises to be a revolutionary procedure that would give people with little hair a chance to have hair transplant surgeries. It would do this by multiplying the hair a patient already has rather than using up the good hair that still exists on the patient’s head.

Hair cloning is done by taking stem cells, or dermal papilla cell, and cloning them in a laboratory setting. They are then multiplied and combined. The end result is an increase in the number of hairs available for hair transplant.

Not only is hair cloning possible, it has been proven in many scientific studies. Recently one group of researchers did a culture whereby they multiplied the number of dermal papilla cells. With this being possible, hair cloning is a single step away.

Hair transplant procedures that use cloned hair are farther off, though. The research cannot be done as to whether these hairs can safely and effectively be transplanted onto a person’s scalp yet. First, they cloning process will have to be completely perfected. Only then can the hair transplant trials begin.

More research needs to be done to find out which hair cells can be used for hair cloning and then hair transplant procedures. Some of the available cells go through several stages before ending in cell death in a very short time. These cells would not be adequate for use with hair transplant surgery. There seem to be other cells which last longer and would work for this application.

A scientist named Dr. Gho has done some work and acquired a Dutch patent on his work with hair multiplication. It is unclear whether this is much like hair cloning or not. That is because Dr. Gho neglects to submit his findings to be published in medical journals. Without review by other doctors, Gho’s theories cannot be tried and evaluated.

Certain types of auto-immune diseases, such as alopecia areata can now be treated by means of hair transplant techniques by using the donor strip method. Yet, in the future, hair cloning will make hair transplant easier for these people who often have very little hair to use for grafts.

Some people believe that hair transplant grafts using cloned hair would be about the same cost as the usual hair transplants that are available today. Other experts believe that the price will be much higher – perhaps three or four times per graft higher – because of the specialized methods required to do the work.

Hair cloning is probably not as far away as one might think. It might be ready for use with hair transplant procedures as soon as five years from now, or even sooner. If you are considering getting a hair transplant but you want to wait awhile, hair cloning is something to think about.

How Doctors are Using Their Skills to Combat Congestive Heart

How Doctors are Using Their Skills to Combat Congestive Heart Failure

Congestive heart failure is an insidious opponent, possessing a slow onset that results in a patient often not even noticing they are having symptoms. Over time the patient will suffer from worsening dyspnea and edema that will eventually drive them to seek treatment, where they will discover that for whatever reason their heart is no longer able to function properly.

Heart failure occurs when the cells of the heart tissue are either destroyed or made non-functional due to another cardiac event, often secondary to ischemic heart disease or coronary artery disease. As a result, the heart is no longer able to pump the blood throughout the body properly; instead the blood pools, resulting in fluids being retained rather than excreted properly and oxygen starved organs being unable to function. The death of these cells is critical because, like brain cells, once the cells of the heart die the body is unable to reproduce them and restore full function to the heart. Congestive heart failure carries with it a high mortality rate, with over fifty percent of its victims dying within five years of being diagnosed. Doctors and researchers are able to use modern advancements in medicine to make the patient more comfortable and, in many cases, to provide them with a more favorable prognosis.

Many patients do not even discover that they have suffered heart failure until they are brought into the Emergency Department of their local hospital complaining of chest pain and difficulty breathing. Doctors will stabilize them there, giving them supplemental oxygen and beginning a course of medicinal treatment that will carry them out of the hospital.

Modern science has provided physicians with a wide array of methods with which to combat the damage done by congestive heart failure. Once oxygen is returned to an acceptable level a physician will usually administer a diuretic to stimulate the renal system to pull fluid out of circulation, relieving the edema and taking a great of stress off of the lungs, heart and other organs. This will also usually be accompanied by supplemental potassium, as the renal system will remove potassium along with the excess fluid and hypokalemia carries with it its own hazards.

A great deal of attention in the field of medicine has been focused on the body’s production of angiotensin II as it aggravates congestive heart failure. Angiotensin II is a substance produced by the body which raises blood pressure and causes the blood vessels to constrict, thereby forcing the heart to work much harder to pump blood throughout the body. An ACE inhibitor will often be administered to prevent the body from making angiotensin II, and an angiotensin receptor blocker is available to those who do not respond as desired to the ACE inhibitor. Many patients with heart problems are given nitroglycerin for this reason.

Along with medicine, research into the field of congestive heart failure is ongoing. The speculated use of stem cells, particularly embryonic stem cells, has opened a whole field of debate for possible treatment of heart failure in the science community. Patients with congestive heart failure were given some of their own stem cells in the heart via injection, and all reacted favorably. Scientists are unsure as to whether this is because the stem cells aid the body in growing new vessels or simply act as a lighthouse for the body’s natural healing mechanisms, drawing other cells to the site of the damage. Whichever the case may be, stem cells present a fascinating opportunity to finally find a means by which to restore heart function to patients who have suffered heart failure.

Modern science is providing a whole new world of treatment options to patients with congestive heart failure, and researchers are making new discoveries all the time. It is the hope of all of those in the medical field that one day heart failure will be another disease medicine has the answer to.

How CHF Patients can Take Advantage of Translational Research?

In nature every action spawns a separate and equal reaction. In the field of medicine, the reaction may not always be equal to the action. The performance of a particular treatment in the lab on test animals may not be the same as would be seen in a human subject; this is where the field of translational research comes in.

Translational research takes research from the laboratory to the patient’s bedside. This can be done in several forms. In its earliest stages a treatment will undergo controlled clinical trials with a voluntary group of test subjects. If these small, controlled tests meet the acceptable range of success the treatment is then taken to research hospitals such as St. Jude’s or Children’s Hospital of Boston. Here patients are given the opportunity to experience new methods of control and treatment of a disease with the understanding that it is still considered highly experimental; however, for many these treatments represent a chance for a cure that previously as out of reach for them as the moon.

Congestive heart failure is, at the moment, an incurable event, occurring when for whatever reason the cells of the heart muscle are destroyed and the heart can no longer adequately pump blood throughout the body. Once the cells in the heart tissue are non-functional the body is unable to replace them, making it impossible for the heart to regain full heart function on its own. The current mortality rate is high, and over fifty percent of patients with congestive heart failure will die within five years of being diagnosed. There are many treatment options currently being considered for congestive heart failure, however, and a number of new technologies being tested daily. For example, Montefiore Medical Center in New York City is currently doing clinical trials on a drug known as Lovosimendan, a calcium sensitizer that does not trigger cardiac arrhythmia, and research into the possibility of using stem cells to regrow cardiac tissue is ongoing.

For a patient to take advantage of these options they should discuss the possibility of being a subject for clinical testing with their physician to see if they would be a good candidate, then allow the physician to make a recommendation on a course of action from there. It may be suggested that the patient contact a research facility, or the physician may suggest their name for a clinical trial they know is occurring soon. If the patient lives in an area with a research hospital nearby, chances are there will be an opportunity for them to benefit from the hospital’s policy on translational research.

It should be understood that translational research is precisely what it sounds like; research. Scientists and doctors are often still learning about the treatment and its effect on the human body, and there is always a possibility that it will be unsuccessful or carry with it many hazardous side effects. These courses of treatments are unknowns to physician and researcher alike. For patients who have run out of options, however, even the possibility of a negative effect cannot stifle what the opportunity to be part of a translational research project provides: hope.