Tag: Genes

Rheumatoid Arthritis Overview

Rheumatoid Arthritis Overview
L. Hirt & eKnowItAll.com

Rheumatoid arthritis is an inflammatory disease that affects your joints. It can cause swelling, stiffness, pain and loss of function in the joints it affects. Unlike other types of arthritis, it does not usually affect just one joint, but the matching joint on the other side of your body as well. The most commonly affected joints are the wrists and fingers. There are several forms of the disease, ranging from a short period of pain lasting for only a year to severe pain that lasts many years or an entire lifetime. SymptomsSymptoms can vary from person to person, but there are several features of the disease that often occur:Tender, swollen and warm joints often in the wrist or fingers Pain affecting the same joints on both sides of your bodyInflammation in other joints such as the knees or hipsProlonged periods of pain and stiffness, after long periods of rest or after waking upOccasional fevers, fatigue, and an overall feeling of not being wellFactors Increasing the Risk of Rheumatoid ArthritisRheumatoid arthritis can be hereditary, and can result from having specific genes that control your immune system. Several genes play a role in whether a person develops the disease, and how severely they are afflicted. Genetics, however, is not the only factor.It is believed that certain events trigger the onset of rheumatoid arthritis in people already susceptible to it because of their genes. The most likely causes are bacterial or viral infections.Women are more likely to develop the disease than men, and their hormone levels may affect the onset of the disease. For example, pregnancy often lessens the severity of the disease, while flare-ups often occur after giving birth.The Basics of Rheumatoid ArthritisJoints, where two bones connect, are normally surrounded by a protective and supportive capsule. The capsule surrounds the joint and the cartilage between the bones. Healthy joints have a lining of a tissue called synovium and produce a fluid that both nourishes and lubricates the bones and cartilage. In people with rheumatoid arthritis, the immune system produces white blood cells that attack the synovium. This causes the inflammation consistent with arthritis, and makes the joint swollen and painful. Once the disease develops, the inflamed synovium actually attacks the joint and its bone and cartilage, working to destroy it. Eventually, the muscles around the joint become too weak to support it properly, causing often severe pain and joint damage. Common TreatmentsNo matter what treatment doctors and patients choose, the goal is always to stop pain and inflammation, prevent further damage to joints and allow the person to function normally.Dealing with the Disease:Splints can be used to support an affected joint, letting it rest. This will reduce swelling and pain. Other simple tools can make daily tasks easier for people with the disease. For example, patients may use special devices to help them get in and out of bed.A healthy blend of rest and exercise is also important. Doctors suggest getting more exercise while the disease is not severe, and getting more rest when attacks flare-up. Exercise improves flexibility, muscle strength, and joint mobility, while also contributing to the patients overall well-being. When resting, it is best to rest for short periods, rather than taking long naps.To reduce the stress involved in coping with the disease, patients can utilize relaxation techniques, regular exercise, and support groups. Eating a balanced diet also contributes to overall well-being.Medication and SurgeryMost people with rheumatoid arthritis take some form of medication. Types include those to relieve pain, to reduce inflammation and to slow the onset of the disease. Common drugs include Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and aspirins. The most effective treatments often include a combination of more powerful medications.Surgery can be performed to reduce pain and improve joint function and daily life. Common surgeries include joint replacement, tendon reconstruction, and synovectomy, in which doctors remove the inflamed synovial tissue. This is done only as part of other reconstructive surgery.For all patients, regular doctor visits, and routine blood and other laboratory tests are important and should be made on a regular basis. About the Author
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Eczema in Children

When a skin rash cannot be blamed on poison ivy or chicken pox, the culprit is eczema. In this condition, the skin turns red, scaly and develops sores. The itching is beyond the limit and the skins starts to shed in the form of scales. Dermatitis is the other name for eczema. Dermatitis actually means inflammation of the skin and the skin turns pink and sore. Eczema is a common child problem as out of ten kids at least one kid gets eczema and majority of them get it before they turn five years old. Children who are above five years are also at a risk of developing eczema, but once they become teenagers, the chances are negligible.

Not only does eczema dries the skin, it also makes it itch horribly. The skin break out can even take the form of rashes. Eczema is a condition which comes and goes frequently and therefore it is chronic. When any foreign bodies come in contact with the skin, a special kind of cells present in the skin will react to them. Basically, they inflame the skin as a measure of protection. The harmful foreign objects trigger the reaction and make these special cells to over react. This turns the skin itchy, sore and red. Children, who get eczema frequently, have a larger quantity of these special cells.

Usually, people who have family members with asthma, hay fever or any allergies are more prone to getting eczema. It is in their genes to get eczema and this problem is passed over to them by their parent. Some scientists say that people, who as children have had eczema, are at a higher risk of developing asthma or hay fever later in their life. Allergies can only make eczema worse. The good news is that eczema is not contagious, so children can be happy about not catching the infection. The first symptom of eczema is rash development. These rashes may seem to go away in the beginning, but will return back. Although eczema itches badly, not all rashes will itch. Eczema will start to develop behind the knees and inside of the elbows. It will slowly spread to the face and other body parts.

Because rashes can be caused due to many other reasons apart from eczema, the doctor will examine the rashes and its cause very carefully. If eczema is confirmed, the child may have to use a moisturizing cream or lotion to stop the itchiness and drying of the skin. In serious cases, the patient will be recommended corticosteroids. It is a steroid cream or ointment which needs to applied to check skin inflammation. If the itching is really irritating, antihistamine can be taken in either liquid or pill form. And if the scratching had resulted in an infection, antibiotics will also be prescribed. The problem doesnt get solved forever, but it makes the condition better for the time being.

There are certain things which trigger eczema and should be avoided by children who get eczema frequently. Perfumes, detergents, soap, dry air in winters with very little moisture, and sweaty and hot skin. Also when coming in contact with dust mites and scratchy fabrics can increase skin irritation. The child must abstain from scratching even if the skin is itching badly, as that will make the skin itch more badly. The skin can also get infected with bacteria because of skin breaking and bleeding. A washcloth can be dipped on cool water and placed on the area of itchiness. The parents should cut the nails short of the child so that he/she doesnt hurt himself while scratching. Lastly, lots of water should be consumed to provide moisture to the dry skin.

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Cause of Alzheimer’s Disease

Alzheimer’s disease is a form of a mental disorder that is also known as “dementia”, a brain disorder that affects and seriously impedes the brain’s ability to process rational or normal thought. This usually results in limiting the amount of daily activities that require the use of cognitive abilities of its sufferers. Alzheimer’s is a debilitating disease because it affects the part of the brain that is responsible for thought, memory, and language.

Alzheimer’s is especially one of the most disabling diseases that can affect the older population. What makes Alzheimer’s disease a very serious affliction is that it is a progressive disorder that can slowly kill the irreplaceable nerve cells in the brain. Although Alzheimer’s is detected more often among patients over 60 years old, there are some individuals as young as 50 years of age who can show signs of Alzheimer’s.

Alzheimer’s disease holds no boundaries. It can equally affect people of different cultures and is found to afflict both males and females in equal proportions. Not one particular test is known to be used for diagnosing Alzheimer’s. A variety of methods and tests are being used to diagnose 90 percent of Alzheimer’s cases. A 100 percent accuracy in diagnosing the disease can only be achieved upon autopsy to check for plaques and tangles in the sufferer’s brain.

The root cause of Alzheimer’s disease is not yet quite well understood despite the many years of research on the debilitating condition. Alzheimer’s is a complex disease that can be caused by a number of different influences.

The main cause of Alzheimer’s disease that researchers today have found out is damaged brain cells that die for unknown reasons. The cause of Alzheimer’s disease, which was first isolated by the German neurologist Dr. Alois Alzheimer, is the abnormal clumping together of brain cells. These clumps, also known as plaques, and knots or tangles which disrupt normal brain functioning, are considered as the main definitive characteristics of Alzheimer’s disease.

Alzheimer’s Disease and Its Cause

Genetics are also being studied as a possible cause of Alzheimer’s disease. Another possible cause of the disease is seen to be a slow developing viral infection that results in brain inflammation. Although the actual cause of Alzheimer’s disease may not yet be known and still in the discovery stages, there are a number of risk factors that is known to increase the likelihood of Alzheimer development.

Age is known as a risk cause of Alzheimer’s disease. As a person ages, the likelihood that he or she will develop Alzheimer’s also increases. The average age of diagnosis for Alzheimer’s is about 80 years old. Gender is also seen as involved in the development of Alzheimer’s disease, but studies for this may still be inconclusive. The reason as to why the risk is seen to be greater in women is that they tend to live longer than the men.

Hereditary tendency is being looked into as another risk cause of Alzheimer’s disease. The presence of some defective genes and genetic mutations within the same bloodlines has also been seen to increase the development of Alzheimer’s disease.

Another possible cause of Alzheimer’s disease that is being looked into is the malfunction of the immune system and protein imbalances that occur in the brain. Certain environmental factors such as the presence of aluminum in the home or workplace are also being put under investigation as a possible cause of Alzheimer’s disease.

Arthritis–Can it be Prevented?

Arthritis–Can it be Prevented?
Karen Cole-Peralat

Overview of Arthritis
Effective help is currently available for people to proactively manage arthritis and enjoy life to the fullest. But the actual prevention of arthritis itself is yet another story.
With rheumatoid arthritis (RA), the membranes or tissues lining the joints become inflamed. There is no known way to prevent any form of this disease, including osteoarthritis, adult-onset arthritis and juvenile rheumatoid arthritis. The exact causes of all these conditions are unknown.
It’s very important for people who fear they are at risk of rheumatoid arthritis to realize that at this time there are no medications to take or lifestyle modifications to make that can completely prevent this crippling disease. However, by making changes to your weight and diet and engaging in moderate exercise, you may be able to slow or even halt the disease’s onset and progress.
But you can only really take the measures needed to control arthritis after it is diagnosed. Until it is known for sure if certain bacteria or viruses trigger the disease, contact with people suffering from it will not change your risk of developing it.
Traditionally, medications and physical therapy have been used to manage the disease. A massive amount of nutrient research has also shown the effect diet and supplements have on the body’s healing processes. Lifestyle changes can also make a big difference.
Causes of the Disease
Joint injuries caused by accidents or overuse increase the occurrence of some types of arthritis. You can also inherit certain genes that may increase your risk. More research is needed to find out how to reduce the disease’s onset from these factors.
Some individuals have an inborn tendency to degenerative joint disease because they have changes in the structure of the important protein-building blocks of the articular cartilage which covers the surface of their joints. These seemingly small but significant abnormalities predispose their joints to wear and degeneration. In other cases, joint injuries may contribute to the development of DJD.
No foods have been definitively shown to cause or exacerbate arthritis in most individuals. A variety of diets and “hand-me-down” information exists about certain foods and arthritis, in particular the night shade plants, but none of it has been proven.
There is a rare form of arthritis called Spure which is caused by allergies to wheat products. Avoiding those will eliminate this disease. Associated features include weight loss, diarrhea and osteoporosis. Consult your health care provider if this is a concern.
There are things you can do to reduce your risk for getting certain types of arthritis or to reduce disability if you already have arthritis.
Overweight and obese people have a higher frequency of arthritis. Excess weight increases risk for developing osteoarthritis in the knees, and possibly in the hips and hands. Women are at special risk. In men, excess weight increases the risk for developing gout. It’s important to maintain your recommended weight, especially as you get older.
Arthritis Prevention Programs
The Center for Disease Control has implemented programs in several states to reduce the onset and consequences of arthritis. The National Arthritis Action Plan: A Public Health Strategy delineates the actions necessary to better understand the arthritis burden in the USA and helps to fully apply known and effective interventions.
This document represents the combined efforts of nearly 90 organizations, such as the Arthritis Foundation, government agencies and many other groups and individuals with an interest in arthritis prevention and control.
The NAAP proposes a nationally coordinated effort for reducing the occurrence of arthritis and its accompanying disability by focusing on these three areas:
1. Surveillance, epidemiology and prevention research to strengthen the science base.
2. Communications and education to increase awareness and provide accurate information about arthritis.
3. Programs, policies, and systems promoting increased quality of life for people with arthritis and facilitating arthritis prevention measures.
The CDC continues to accumulate scientific knowledge on the benefits of physical activity. Because healthy eating reduces a person’s risk of becoming overweight, good nutrition plays an important role in preventing knee osteoarthritis. In addition, moderate physical activity is essential for maintaining the health of joints.
The information outlined in this article is originally from: HealingWithNutrition.com, Arthritis Facts, Disease Prevention and Treatment Strategies, http://www.healingwithnutrition.com ; Center for Disease Control, Framework for Arthritis Prevention and Control, http://www.cdc.gov ; Web MD Health, http://mywebmd.com ; and the University of Washington Orthopaedics and Sports Medicine, http://www.orthop.washington.edu , Frequently Asked Questions About Arthritis.
About the Author
Executive Director and President of Rainbow Writing, Inc., Karen Cole-Peralta writes. RWI at http://www.rainbowriting.com/ is a world renowned freelance writing, copyediting, ghostwriting, graphics and CAD, search engine optimization, publishing helpers, internet marketing, free professional services, and supercheap dedicated web host and website development corporation.