Tag: Congestive Heart Failure

How Can Genes Contribute to and Cure Congestive Heart Failure?

How Can Genes Contribute to and Cure Congestive Heart Failure?

It is common knowledge that heart failure follows another severe form of heart damage; however, until now scientists and doctors have had no way to identify those at risk. New research into genes and gene therapy have made them a potential weapon in the fight against heart failure.
Scientists have made several discoveries regarding the role of genes in the detection and treatment of heart failure. Several years ago it was discovered that a small percentage of patients who had suffered heart failure possessed a defect in the gene that allows the body to detect stress signals; in essence, the heart does not know that it is working to hard and is unable to adjust. This percentage may seem insignificant; however, the gene mutation was not present in any of the healthy patients examined. Researchers stress that this is a susceptibility factor, not a cause of congestive heart failure; however, it may be the breaking point when determining if a heart suffering from other disease will fail. Detection of this mutation may allow doctors to identify and treat patients at risk prior to their heart failing rather than after.

This defect is found in the ATP-sensitive potassium channels and is caused by a genetic mutation. The potassium channel regulates potassium and calcium levels in the body. While the heart must have calcium to function, an excess of calcium leads to damage. This is the reason calcium blockers are often given to patients with congestive heart failure. Fortunately, medications to open the potassium channel already exist.

In addition, a defect of the delta-sarcoglycan gene has been seen in hamsters with muscular dystrophy and cardiomyopathy. This gene is the cytoskeleton of muscle fibers, and successful transplant of a normal human delta-sarcoglycan gene has been shown to cause a tremendous improvement in these animals. This is noteworthy because current transplant attempts require open heart surgery. This type of gene transplant is carried on a virus, eliminating the need for surgery.

Scientists had been a bit concerned with using this method of gene therapy due to the need for a systemic effect. There was also some concern that the body’s natural immune system would eliminate the virus of its own accord prior to successful delivery of the gene; however, they believe they have found the best form of virus to successfully slip past the body’s defenses. When transplanting the delta-sarcoglycan gene researchers used a type eight adeno-associated virus, piggybacking the corrective gene onto it as it was inserted into the body. This allowed the gene to be carried to all areas of the body in animals with muscular dystrophy without being destroyed by the body’s own natural immunity.

Gene therapy is still highly experimental, and researchers are unsure yet of the role it will play in the conquest of heart failure; however, this represents a technology that was unavailable thirty years ago. Continuing advancements in technology and medicine’s knowledge of the body’s building blocks may one day unlock the mysteries to the cure of this deadly disease.

How Can Continuing Medical Education Credits Be Obtained?

While physicians spend many, many years in school prior to receiving their MD, it is impossible for them to learn everything there is to know. The medical field is simply too vast, and it is constantly in motion; therefore, it is important that every physician complete continuing medical education.

Continuing medical education (CME) allows a physician to stay abreast of new discoveries, treatments, and other advancements in their chosen field. What worked thirty years ago is not usually the method of choice for today’s physicians, and clinicians who do not complete these continuing education credits may often be placing their patients at risk because of a lack of knowledge of treatments that have been deemed ineffective or hazardous. Unfortunately, often when a physician is wrong it is the patient‘s life that pays the price.

Due to this, every physician is required to complete a minimum number of CME credits every year; however, they are certainly not required to stop once that number is met. This does not necessarily mean returning to school, although this is certainly an option; however, for most physicians caring for their patients leaves them little time for the heavy workload of a secondary education institution. Many other more convenient options are available to them.

Across the nation hundreds of thousands of medical conventions, symposiums, workshops and conferences are available to healthcare professionals, covering topics from new surgical techniques to treat collapsed heart valves to the use of stem cells to treat congestive heart failure; all cutting edge technology not yet taught in the classroom. These often take place over the course of a weekend, often last more than one day and are held in various locations, so physicians from any location in the country may attend at their discretion.

In many rural areas there is only one doctor available, often with no one to see to their patients when they are unavailable. These are the physicians who are still on call twenty four hours a day, make their own hospital rounds and see patients from birth to death for everything from a toothache to a heart attack. Needless to say they are often unable to get away from their practice to attend weekend workshops. Another option is available for them so they can continue to provide their patients with around the clock care. The internet has opened up a whole new world to the field of continuing education. Many organizations, such as the American Medical Association (AMA) and the American Association for Continuing Medical Education (AACME) offer resources online for healthcare workers to complete their continuing medical education credits. Here clinicians will have the opportunity to complete coursework online, view online conferences and use the teleweb to attend lectures and symposiums.

These CME resources may be found free of charge or for a small fee per credit hour, depending on the situation; however, this is infinitely less expensive (and time consuming) than returning to a college or university, and offer greater benefits because attendees are able to stay apprised of new research and untried methods that are not taught to students.

It is true that no one ever stops learning, and this is especially true in the medical field. Continuing medical education allows clinicians to stay on top of their field and provide the best, most advanced care options available to their patients.

Heart Failure

Whenever cardiac conditions develop these conditions, weaken or damage your heart, which leads to heart failure. In a weakened condition, the heart over time can no longer keep up with even the normal demands placed on it. The ventricles may become stiff and not fill properly between beats. The heart ventricles stretch (dilate) to the point that the heart cannot pump blood efficiently throughout your body. The failing pump causes blood and fluid to back up throughout your circulatory system. The circulatory system consists of your lungs, legs, feet and ankles. The kidneys retain excess water and sodium. All this builds up is the congestive part of your heart failure. The lung congestion occurs only with left-sided heart failure with fluid backing up into the lungs. The most common cause of right sided heart failure is left sided heart failure.

When the fluid fills up the left side of the heart the pressure in the lungs passes to the right side of the heart, which then fails. The fluid then collects in the abdomen and lower extremities which all leads up to heart failure. Heart Failure develops quickly after a heart attack. The heart failure can also develop after years of high blood pressure or coronary artery disease. A defective valve may cause heart failure. A heart valve replacement in this case will prevent heart failure. A specialist normally does the surgical part, which is a cardiologist.

Many times people think that such things cause heart failure as smoking, being overweight or eating foods high in cholesterol and fat but there is a condition known as idiopathic dilated cardiomyopathy were the heart weakens without explanation. This condition will also cause you congestive heart failure if not properly taken seriously.

You might be suffering from if you have heart failure several conditions. These conditions can weaken your heart over time and be present without you being aware that you have the problem. The follow is a brief description of some conditions that affect the heart:

– The most common cause of heart failure is Coronary artery disease. A process called atherosclerosis, which is a build up of fatty deposits in the arteries. This fatty build up causes the blood to narrow a process called plaque, which leaves chronically deprived of oxygen-rich blood pump less vigorously. A heart attack occurs if an unstable plaque not function well it will cause a blood clot in turn completely blocks the blood flow to an area of the heart muscle. This is one of the most common causes of heart failure.

– There are several other reasons that might cause heart failure but we shall discuss the next highest reason for now. High Blood Pressure (hypertension) is the force of blood pumped by your heart through your arteries. When your blood pressure is high then your heart has to work harder causing failure.

Take your cardiologists advice watch your weight and exercise your on the way to a heart healthy way of life.

Enjoy the Highest Quality of Life Possible With Congestive Heart

Enjoy the Highest Quality of Life Possible With Congestive Heart Failure

There is no doubt about it, cardiac complications can impact every corner of life, forcing patients to forego activities they previously enjoyed and causing them to feel as though they have sacrificed their life to save it. There are, however, many steps patients can take to allow them to enjoy life even after having been diagnosed with heart failure.

Congestive heart failure occurs when the cells of the heart are unable to constrict properly and pump blood through the body. This results in edema throughout the body, particularly in and around the lungs and is the cause of the dyspnea that is typical of heart failure. To counteract this, patients should take any diuretics prescribed by their doctor and maintain a low sodium diet, allowing the excess fluid to leave through the renal system and making it easier for the patient to breathe. Daily exercise is important; it is not necessary that it be vigorous, patients should consult with their physician prior to embarking on an exercise regime to ensure that they will not be taxing their heart unnecessarily. It is possible that if a patient has previously enjoyed activities that put a great deal of strain on the heart they will find it necessary to restrict themselves to less stressful endeavors; however, with the proper precautions many physical activities are still permitted.

The heart pumps blood more easily when the body is at rest; therefore, it is essential that patients with heart failure schedule time daily to rest. They may sit and read or watch television, take a nap or meditate; any activity that allows the body time to recharge. Meditation is being considered as a possible method of treatment for patients suffering from heart failure; meditation causes the heart to beat slower, blood pressure to normalize, the muscles to use oxygen more efficiently and the body to produce less adrenaline. All of these factors make it easier for the heart to function.

Any patient suffering from heart failure should abstain from smoking. Inhaling nicotine causes the body’s blood pressure and heart rate to increase, less oxygen to reach the muscles and an increased clumping and stickiness in blood vessels that may impede blood flow. All of these factors cause the heart to beat harder in an attempt to compensate, placing more stress on an already weak heart.

Patients should also avoid flu and pneumonia as much as possible, avoiding crowded areas during cold and flu season and receiving both an annual influenza vaccination and at least one dose of the pneumococcal vaccine (this will provide some protection against pneumococcal bacteria, the most common cause of bacterial pneumonia). The decreased oxygen in the blood resulting from either flu or pneumonia will result in the heart pumping harder in an attempt to compensate.

Everything in their life affects a patient’s well being when they are suffering from congestive heart failure, right down to their clothing. These patients should avoid restrictive clothing and stockings as much as possible, as these items present an increased risk for clotting and a blockage of blood to the extremities. They should also avoid temperature extremes as much as possible and dress appropriately for the weather; the body must work much harder to maintain temperature when it is either extremely hot or extremely cold.

The most beneficial thing that patients suffering from heart failure can do to allow them to enjoy their life is to enjoy their life. The negative effects of stress on the heart are well documented, and patients who live a stress free existence create a much better environment for their heart than those who are unhappy or overworked. So by maintaining a positive mental state, patients are able to help themselves both emotionally and physically.