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My Rude Introduction to Arthritis and how I am Coping

My Rude Introduction to Arthritis and how I am Coping with It
Jimmie Newell

Let me begin by stating upfront that I realize that a great many people suffer from much more serious arthritic conditions than I. This article is not to trivialize their conditions in any way. My intent is to explain how this disease manifested itself in me and the treatment that I have undertaken.Being an avid golfer, I like many other men can hardly wait for spring to arrive. In 2004 spring came early. My first round I walked 18 holes with a push cart as I usually do. I did not feel any abnormal pain at this point. The next day I went to the driving range to work some of the kinks out of my swing, and hit a large bucket of balls. Later that evening my left knee was in so much pain that I could not stand with any pressure on it, walking was very painful. This persisted for 2-3 weeks, it did finally start to get better, but only marginally, golf had been degraded to using a power cart, there was just no way I could walk 9 holes, let alone 18. Making any full swing was painful from the pressure put on my left knee.I finally went to an Orthopedist, and after x-rays of both knees and a range of motion exam, was told that I had Osteoarthritis. The doctor showed me the small space left between the bones of my left knee, and told me that the meniscus (a pad of cartilage that cushions the joint and prevents bone to bone contact) was thinning and was in all likelihood torn. He told me that a few years ago, the standard treatment was to surgically repair the meniscus . however this type of repair was only effective at relieving pain about 50% of the time.The more accepted treatment now, was to prescribe a series of exercises designed to strengthen the muscles around the knee joint, and a pain reliever to control the pain, so that I could exercise. He also suggested that I investigate and take glucosamine which is a natural healing product not regulated by the FDA. He stated that recent large scale studies had shown that glucosamine was effective in slowing down the loss of cartilage and may even contribute to regeneration of damaged cartilage.Because I had previously had problems using Ibuprofen, he prescribed “Bextra” (a cox 2 inhibitor drug) that seemed very effective. Of course 2 weeks later came the scare about “Vioxx” also a cox 2 inhibitor drug, and I stopped taking “Bextra”, which is now not prescribed by many doctors. I started taking Ibuprofen again, however only in great moderation, I have had no ill effects. I continued with the exercises, some gradual improvement was noticed. I also continued taking glucosamine.All of these measures have contributed to effective pain relief, however even more relief was noticed after losing about 10 lbs. This reinforces the notion that excess weight plays a large role in knee pain.As of now (going into spring of 2005) the pain seems to be under control, my activity with the possible exception of running, is not restricted in any way. And my golf swing, once again needs work!Resources for more information:Arthritis and Glucosamine Information Center – http://www.glucosamine-arthritis.org/Flexicose HomepageArthritis FoundationNational Institute of Arthritis and Musculoskeletal and Skin DiseasesJohns Hopkins Arthritis Center Arthritis National Research FoundationCenters for Disease Control and Prevention Arthritis InsightTo Your Health,Jim Newell About the Author
Jimmie Newell is the webmaster for http://www.ToYourHealth101.com, a health & wellness website, featuring editorials, tips, information and links addressing many of the health issues of today.

Hair Cloning Research for Hair Transplant Procedures

The future of hair transplant procedures is in the laboratories at this very time. Scientists are working together to find a way to make the surgery work for more people. They also want to see it work better for the types of people who have hair transplants today. One area of research is hair cloning.

Hair cloning promises to be a revolutionary procedure that would give people with little hair a chance to have hair transplant surgeries. It would do this by multiplying the hair a patient already has rather than using up the good hair that still exists on the patient’s head.

Hair cloning is done by taking stem cells, or dermal papilla cell, and cloning them in a laboratory setting. They are then multiplied and combined. The end result is an increase in the number of hairs available for hair transplant.

Not only is hair cloning possible, it has been proven in many scientific studies. Recently one group of researchers did a culture whereby they multiplied the number of dermal papilla cells. With this being possible, hair cloning is a single step away.

Hair transplant procedures that use cloned hair are farther off, though. The research cannot be done as to whether these hairs can safely and effectively be transplanted onto a person’s scalp yet. First, they cloning process will have to be completely perfected. Only then can the hair transplant trials begin.

More research needs to be done to find out which hair cells can be used for hair cloning and then hair transplant procedures. Some of the available cells go through several stages before ending in cell death in a very short time. These cells would not be adequate for use with hair transplant surgery. There seem to be other cells which last longer and would work for this application.

A scientist named Dr. Gho has done some work and acquired a Dutch patent on his work with hair multiplication. It is unclear whether this is much like hair cloning or not. That is because Dr. Gho neglects to submit his findings to be published in medical journals. Without review by other doctors, Gho’s theories cannot be tried and evaluated.

Certain types of auto-immune diseases, such as alopecia areata can now be treated by means of hair transplant techniques by using the donor strip method. Yet, in the future, hair cloning will make hair transplant easier for these people who often have very little hair to use for grafts.

Some people believe that hair transplant grafts using cloned hair would be about the same cost as the usual hair transplants that are available today. Other experts believe that the price will be much higher – perhaps three or four times per graft higher – because of the specialized methods required to do the work.

Hair cloning is probably not as far away as one might think. It might be ready for use with hair transplant procedures as soon as five years from now, or even sooner. If you are considering getting a hair transplant but you want to wait awhile, hair cloning is something to think about.

How Doctors are Using Their Skills to Combat Congestive Heart

How Doctors are Using Their Skills to Combat Congestive Heart Failure

Congestive heart failure is an insidious opponent, possessing a slow onset that results in a patient often not even noticing they are having symptoms. Over time the patient will suffer from worsening dyspnea and edema that will eventually drive them to seek treatment, where they will discover that for whatever reason their heart is no longer able to function properly.

Heart failure occurs when the cells of the heart tissue are either destroyed or made non-functional due to another cardiac event, often secondary to ischemic heart disease or coronary artery disease. As a result, the heart is no longer able to pump the blood throughout the body properly; instead the blood pools, resulting in fluids being retained rather than excreted properly and oxygen starved organs being unable to function. The death of these cells is critical because, like brain cells, once the cells of the heart die the body is unable to reproduce them and restore full function to the heart. Congestive heart failure carries with it a high mortality rate, with over fifty percent of its victims dying within five years of being diagnosed. Doctors and researchers are able to use modern advancements in medicine to make the patient more comfortable and, in many cases, to provide them with a more favorable prognosis.

Many patients do not even discover that they have suffered heart failure until they are brought into the Emergency Department of their local hospital complaining of chest pain and difficulty breathing. Doctors will stabilize them there, giving them supplemental oxygen and beginning a course of medicinal treatment that will carry them out of the hospital.

Modern science has provided physicians with a wide array of methods with which to combat the damage done by congestive heart failure. Once oxygen is returned to an acceptable level a physician will usually administer a diuretic to stimulate the renal system to pull fluid out of circulation, relieving the edema and taking a great of stress off of the lungs, heart and other organs. This will also usually be accompanied by supplemental potassium, as the renal system will remove potassium along with the excess fluid and hypokalemia carries with it its own hazards.

A great deal of attention in the field of medicine has been focused on the body’s production of angiotensin II as it aggravates congestive heart failure. Angiotensin II is a substance produced by the body which raises blood pressure and causes the blood vessels to constrict, thereby forcing the heart to work much harder to pump blood throughout the body. An ACE inhibitor will often be administered to prevent the body from making angiotensin II, and an angiotensin receptor blocker is available to those who do not respond as desired to the ACE inhibitor. Many patients with heart problems are given nitroglycerin for this reason.

Along with medicine, research into the field of congestive heart failure is ongoing. The speculated use of stem cells, particularly embryonic stem cells, has opened a whole field of debate for possible treatment of heart failure in the science community. Patients with congestive heart failure were given some of their own stem cells in the heart via injection, and all reacted favorably. Scientists are unsure as to whether this is because the stem cells aid the body in growing new vessels or simply act as a lighthouse for the body’s natural healing mechanisms, drawing other cells to the site of the damage. Whichever the case may be, stem cells present a fascinating opportunity to finally find a means by which to restore heart function to patients who have suffered heart failure.

Modern science is providing a whole new world of treatment options to patients with congestive heart failure, and researchers are making new discoveries all the time. It is the hope of all of those in the medical field that one day heart failure will be another disease medicine has the answer to.

Psychiatric Evidence of Bipolar Disorder

Bipolar disorder, or manic depression, is a serious mental illness that has eluded doctors for decades. For many years, bipolar disorder patients were diagnosed as psychotic or Schitsophrinia. However, about twenty years ago, manic depression became a more common diagnosis. Psychiatric specialists still, however, did not really understand the illness.

Over time, more psychiatric evidence has come to light that proves that bipolar disorder, as it is now called, is actually caused by chemical imbalances in the brain. Other factors, both medical and situational, can be involved as well. In the last few years, psychiatric specialists and researchers have determined that bipolar disorder actually has varying degrees of severity, as well as types of symptoms.

Studies of bipolar patients conducted by psychiatric professionals and researchers has long suggested that bipolar disorder runs in families, or, in other words, is hereditary. Through careful study and research of the functions of the brain, it has now been determined how this illness is indeed hereditary and biological in nature.

According to research posted in the American Journal of Psychiatry in 2000, patients with bipolar disorder actually have thirty percent more brain cells of a certain class that have to do with sending signals within the brain. These additional brain cells cause patients’ brains to actually behave differently, making them predisposed to have periods of mania or depression.

According to researchers, this type of brain cell regulates moods, how someone responds to stress, and cognitive functions. When the extra brain cells are present, a congestion of cells regulated one type of mood or cognitive function is overloaded, and therefore causes a bout of mania or depression. It is not yet known by psychiatric researchers, however, why patients with bipolar disorder have these additional brain cells. To discover this, more genetic research will be required.

In addition to brain cells and brain chemistry, it has also been speculated by psychiatric researchers that various genes in the genetic makeup of bipolar patients can also contribute to the cause of and hereditary nature of bipolar disorder. Studies have been ongoing experimenting with removal of the gene in mice. The evidence suggests that circadian genes, which regulate mood, hormones, blood pressure, and heart activity may be linked to bipolar disorder. Specifically, the absence or abnormality of the gene actually seems to bring about mania episodes.

All in all, more research needs to be done. Medical and psychiatric researchers and doctors have a lot more to learn about the brain and how it functions. While current treatments seem to work for bipolar disorder, they also have severe side effects. Often, medications prescribed for bipolar disorder have to be monitored, dosages modified, or medications switched entirely for patients to maintain balance. The more we learn about the brain and it’s functions, the more we can learn about the physical, biological causes of bipolar disorder. The more we learn about the causes of bipolar disorder, the more likely it will become that effective treatments can be found that offer little side effects and more permanent treatment options for bipolar patients.