Tag: World Health Organization

Tamiflu And Relenza Against Swine Flu

Newsbreak on the flash: A new strain of Swine Flu that has killed 149 and sickened nearly two thousand in Mexico has spread to the United States and is raising fears of a possible pandemic. Through this article you will learn more about the disease and why it is causing concern among health officials and inform the readers about the two suggested antiviral drugs by Centers for Disease Control and Prevention (CDC) to fight Swine Flu pandemics.

This prescription of antiviral medication that can be used to treat influenza infections between children and adults is called Tamiflu. If their symptoms have started within the last two days they are advice to start taking the Tamiflu. This antiviral medication can also be used to prevent children, teens and adults if they are exposed to the influenza virus.

Relenza (ruh-LENS-uh) is more active than the Tamiflu. This kind of medicine, aside from treatment of influenza they can also prevent the suspect to getting the flu again. While some antiviral medicines only protect against influenza A, Relenza is effective against both influenza A and B. This Relenza drug belongs to neuramidase inhibitors group of medicines. These medications target the influenza virus and prevent it from spreading inside your body.

Relenza treats the cause of influenza at its source, rather than simply treating the symptoms like the role of Tamiflu. Simulations suggest that if physicians choose a second effective antiviral such as zanamivir. Zanamivir is the generic name of Relenza as first-line treatment in even a few percent of cases, but can solve to delay the spread of resistant strains.

The available antiviral treatments for influenza, the virus is resistant to rimantadine and amantadine, but sensitive to the oseltamivir and zanamivir. Oseltamivir is the generic name Tamiflu. This strain may mutate develop resistance of oseltamivir in the future.

Tamiflu and Relenza is highly recommended by the CDC for both treatment and prevention of the new strain. The shelf life of federally stockpiled Tamiflu from the original five years to seven years because studies indicated that the medication continues to maintain its effectiveness had already extended by the United States government and Roche Applied Science. Not only that, the other members of the G8 Countries extended their contract stockpiled of Tamiflu from vaccine manufacturers.

It is highly recommended not to buy from online pharmacies without an address of these two types of medications because their stockpiled are counterfeited. Consult to the World Health Organization for information about the antiviral drugs before making any steps in your country.

Medical experts warned the public not to take the antiviral drugs if you are not ill. You only want to be safe but the worst thing is if you take any of this antiviral drugs may lead you to a virus developing drug resistance. They suggest that antiviral drug should be taken only to very sick people or an individual with low immune system.

From the undetermined source that only one out of three Americans would get Swine Flu vaccine or antiviral drugs. So, it means the vaccine manufacturers especially the manufacturers of Tamiflu and Relenza have no enough capability to do more drugs against the pandemics.

According to CDC, testing has found that the Swine Flu virus remains at risk to two common antiviral drugs, Tamiflu and Relenza.

Swine Flu: The New Pandemic

Everyone’s all abuzz with panic nowadays it seems. That’s mostly because after SARS and bird flu, another new strain of virus has managed to rear its head. The H1N1 influenza virus, more popularly known as the swine flu, exploded on to the global scene last April via a large-scale infection in Mexico City.

I think everyone’s seen the images on CNN a thousand time. Surgical-masked Mexicans crowding the hospitals with worrisome shots of full hospital beds.The Center for Disease Control and the World Health Organization raised their alert levels in hopes of catching and cutting off the infection at the bud, but it seems that cases have been reported all over the world. It seems that the current fatalities from disease are from Mexico but everyone is just expecting for the other shoe to drop.

To understand all of this panic, ypou need to have a little background. Influenza, or more popularly known as the flu, is probably one of the most infectious diseases out there. Airborne and highly contagious, it could spread like wildfire all across the world. Now you’re asking what’s the matter with a few people getting a bit of sniffles? That’s because this isn’t your ordinary flu.

A lot of the flu viruses we are exposed to have been in the human system for hundreds of years. We’ve managed to build an immunity to these strains. The big problem that’s got everyone running scared is the idea that a flu strain has crossed species. This is what happened with the bird flu and now, with the swine flu. The pigs and birds have also built up resistances to these diseases, however, since humans are not used to them, these strains of flu have a very large potential of being fatal.

The last time a large-scale flu epidemic raged around the world, electricity was just coming into vogue and cars were all Model Ts. The Spanish Flu Epidemic of 1918 literally set the bar for every modern disease in terms of casualties. Fifty to a hundred million people worldwide died over a period of two years from 1918 to 1920 as the disease spread worldwide. Following on the heels of the Great War, it was a one-two punch that killed an entire generation of young men and women. What everyone’s afraid of is this: the 1918 epidemic was a subtype of the H1N1 flu virus, the same virus that seems to have crossed over and become a real threat to humans.

This is why the CDC is keeping a close watch on Mexico and hoping all of the subsidiary cases worldwide aren’t indications of the beginning of some worldwide epidemic. The good news about this is that the disease is treatable. Medicine and vaccine production alerts have been sent out by the CDC and most pharmaceutical companies have started churning out oseltamivir and zanamivir.

The problem with that is the demand may outstrip the supply depending on the swine flu’s virulence. More common antiviral drugs are also available but they’re not exactly definitive cures. They serve to weaken the symptoms and give you a fighting chance and prevent some of the worse flu symptoms like diarrhea and vomiting.

So as the world waits and watches the situation in Mexico, it would be a good idea to take a few precautions. Regular hand washes and vitamins can help make sure you avoid the initial infection of the swine flu. Avoiding pork’s not needed though. Swine flu can’t be transmitted through food. Remember to just a take a few preventive measures and you can come through clean and healthy.

Swine Flu Vaccine Productions

To discuss and make strong decisions to fight the widespread Swine Flu, the World Health Organization set a meeting with the vaccine manufacturers together with other health experts to stop the Swine Flu Outbreak. Different Pharmaceutical companies are ready to begin making a Swine Flu vaccine but as the virus may alter, there are questions formed:

How much should they have to produce? How will the government distribute the vaccines to the infected areas? Who should get it, babies, youngsters, adults, men, women, pregnant?

Most flu vaccine companies mentioned that they can only make one vaccine at a time: either seasonal flu vaccine or pandemic vaccine. Production takes months and it is impossible to switch halfway through if health officials make a mistake. Vaccine makers can make limited amounts of both seasonal flu vaccine and pandemic vaccine though not at the same time but they cannot make massive quantities of both because that exceeds manufacturing capacity.

Even if we are in the modern era, still the health officials have a big problem to solve the spreading of deadly swine flu is, and whether they will need more seasonal flu vaccine or swine flu vaccine. Scientists are not sure the effectiveness of a vaccine, if the swine flu will transmute. Only two billion doses of swine flu vaccine could be produced annually based on the estimation of World Health Organization officials, though the first batches wouldn’t be available for four to six months.

A “seed stock” to make the vaccine, which should be ready and it will be distributed to manufacturers worldwide so they can start producing the vaccine is now on the go as the U.S. Centers for Disease Control and Prevention works on. After the vaccine manufacturers get the seed stock, they won’t know how many doses of vaccine they can make or how long that would take.

Including vaccine producer, GlaxoSmithKline PLC, the World Health Organization is under negotiation process to save some of their swine flu vaccine for poorer nations. A couple of years ago members of the rich nations like United States, Switzerland, France, Denmark, Canada and Britain signed deals with the vaccine makers to guarantee them pandemic vaccines as soon as they’re available.

Cipla (The pharmaceuticals giant in India) instructed by the World Health Organization to make a generic version of Tamiflu antiviral drug. Tamiflu also known as oseltamivir, one of the two antiviral drugs to treat the Swine Flu. Then WHO said Cipla’s generic version was more effective than the original made by Swiss firm Roche Holding AG and would hopefully make the drug more accessible to the third world countries. As we all know that Indian pharmaceuticals produce drugs in very affordable prices.

North America has been the hardest-hit continent for the Swine Flu virus that kills two Americans from Texas (including a pregnant woman) and one in Washington. If the vaccine productions are enough to all suspected Swine Flu carrier, it wont happen again that a simple pregnant woman died fighting the virus.

Through this article, we will inform the public of an early planning and prevention against Swine Flu for their safety. Consult to the Health Officers about planning and prevention against the virus. According to an unidentified source that one out of three Americans can only take the Tamiflu.

Swine Flu Vaccine Close To Reality According to Experts

Officials of the Federal government believe that the swine flu vaccine that would protect all Americans from future H1N1 outbreaks would be available by January or late November at the earliest.

HoTop of Form

wever, countries outside the United States and other nations that manufacture vaccines would take several years to generate sufficient vaccines to meet global demands.

Although manufacturing of the vaccine is faster than it was a few years back, it may still not be enough to prevent death and illness if the dreaded virus begins to spread and becomes virulent, experts predict.

In the United States, the main obstacle despite long years of effort remains to be the 50-year old technology they use in manufacturing flu vaccines. The Federal government had invested time and billions of dollars shifting to a quicker and more reliable method.

One such procedure involves cultivating the vaccine viruses in vats of cells instead of hen’s eggs. There are several small companies that are developing new methods that would pave the way for the creation of large volumes of vaccines in a span of weeks.

Dr. Greg Poland, who is the head of the vaccine research program at the Mayo Clinic, admits that the cell-based cultivation technology is not yet available while the never technologies have not yet been proven to satisfy most experts.

In addition, government officials have also not yet decided on whether or not H1N1 is a potential risk that demands production of vaccine. However, they are implementing the initial steps. Andrin Oswald, Chief Executive of the Vaccine Division of Novartis, revealed that one possible problem would be the manufacture of vaccines for swine influenza could hamper the production of seasonal flu vaccines for the coming winter. The most likely thing to do is to compromise, according to Oswald.

However, Robin Robinson, who manages the Emergency Preparation Research Program of the Department of Health and Human Services, believes that majority of manufacturing efforts of vaccine makers would have been completed by June.

According to Dr. Robinson, if the manufacture of the H1N1 vaccine would commence after that, the first 50 million to 80 million would be ready by September.

Dr. Robinson continued by saying that the entire 600 million doses, which are sufficient to give the required two shots for every American would be available by January. Adding the immune stimulant adjuvant to the vaccine could greatly reduce the required dosage, paving the way for the availability of the doses by the latter part of November.

The vaccine industry in the country is now very much capable of responding to the outbreak than it was five years back, when there were only two vaccine manufacturers and encountered a severe shortage. At present, there are five manufacturers supplying vaccines to the domestic market. The vaccine industry, which is used to be the backwater of the pharmaceutical industry, is generating new investments, as a result of government subsidies and higher cost for vaccines.

Despite of this, a World Health Organization and International Federation of Pharmaceutical Manufacturers and Associations revealed that it would still require four more years of manufacturing to meet global demands for a vaccine that would provide protection against bird flu strain that has been the major concern of health officials over the last few years.

Finally, the Federal government is encouraging manufacturers to shift their production in the United States, since all except Sanofi Aventis is now importing swine flu vaccines.