Swine Flu Vaccine Close To Reality According to Experts

Officials of the Federal government believe that the swine flu vaccine that would protect all Americans from future H1N1 outbreaks would be available by January or late November at the earliest.

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wever, countries outside the United States and other nations that manufacture vaccines would take several years to generate sufficient vaccines to meet global demands.

Although manufacturing of the vaccine is faster than it was a few years back, it may still not be enough to prevent death and illness if the dreaded virus begins to spread and becomes virulent, experts predict.

In the United States, the main obstacle despite long years of effort remains to be the 50-year old technology they use in manufacturing flu vaccines. The Federal government had invested time and billions of dollars shifting to a quicker and more reliable method.

One such procedure involves cultivating the vaccine viruses in vats of cells instead of hen’s eggs. There are several small companies that are developing new methods that would pave the way for the creation of large volumes of vaccines in a span of weeks.

Dr. Greg Poland, who is the head of the vaccine research program at the Mayo Clinic, admits that the cell-based cultivation technology is not yet available while the never technologies have not yet been proven to satisfy most experts.

In addition, government officials have also not yet decided on whether or not H1N1 is a potential risk that demands production of vaccine. However, they are implementing the initial steps. Andrin Oswald, Chief Executive of the Vaccine Division of Novartis, revealed that one possible problem would be the manufacture of vaccines for swine influenza could hamper the production of seasonal flu vaccines for the coming winter. The most likely thing to do is to compromise, according to Oswald.

However, Robin Robinson, who manages the Emergency Preparation Research Program of the Department of Health and Human Services, believes that majority of manufacturing efforts of vaccine makers would have been completed by June.

According to Dr. Robinson, if the manufacture of the H1N1 vaccine would commence after that, the first 50 million to 80 million would be ready by September.

Dr. Robinson continued by saying that the entire 600 million doses, which are sufficient to give the required two shots for every American would be available by January. Adding the immune stimulant adjuvant to the vaccine could greatly reduce the required dosage, paving the way for the availability of the doses by the latter part of November.

The vaccine industry in the country is now very much capable of responding to the outbreak than it was five years back, when there were only two vaccine manufacturers and encountered a severe shortage. At present, there are five manufacturers supplying vaccines to the domestic market. The vaccine industry, which is used to be the backwater of the pharmaceutical industry, is generating new investments, as a result of government subsidies and higher cost for vaccines.

Despite of this, a World Health Organization and International Federation of Pharmaceutical Manufacturers and Associations revealed that it would still require four more years of manufacturing to meet global demands for a vaccine that would provide protection against bird flu strain that has been the major concern of health officials over the last few years.

Finally, the Federal government is encouraging manufacturers to shift their production in the United States, since all except Sanofi Aventis is now importing swine flu vaccines.

In Dire Need of Swine Flu Vaccine

According to the World Health Organization, efforts for developing a swine flu vaccine has been ongoing since the first human case of the virus has been confirmed. Estimates place the initial doses of the vaccine will be administered in 5 to 6 months time.

While people diagnosed with H1N1 virus seems to be headed for recovery, there have been deaths recorded. Aside from that, receiving vaccines for this virus is important particularly the elderly and individuals with a weak immune system, since they are prone to complications such as pneumonia.

Likewise, the vaccine will serve as protection in case the condition persists particularly during the winter months which is the time when influenza is at its peak.

According to the World Health Organization (WHO), although they are still incomplete, current evidence shows that seasonal influenza vaccines will provide minimal or no protection against swine flu. Every year, a new batch of flu vaccine is developed and matched with strains that the WHO determines will most probably circulate in the winter months, which happens to be the peak season for influenza outbreaks.

Influenza virus comes in various strains which contains different proteins on their surfaces. The body’s immune system can only fight and destroy a virus if they are able to recognize these proteins. It is worth noting that antibodies that recognize one strain may not detect other strains.
Existing vaccines may only offer some protection against swine influenza if the proteins on its surface are identical to strains used to develop previous vaccines. According to the NIBSC, they are trying to determine if the swine flu virus, which is an H1N1 strain of type A influenza, as well as previous H1N1 vaccines match current vaccines.

The preparation of a vaccine commences after a virus develops as they provide the starting point for the production of the vaccine. As such, there is always a time delay while a vaccine is being developed. Preparation of a vaccine involves several steps so it would take several months before a vaccine becomes available.

According to WHO estimates, the virus needed for producing the vaccine will be accessible to vaccine manufacturers by the middle of May while the initial dose for a new vaccine would be ready within 5 to 6 months after that. Waiting time would be much longer if the growth of the vaccine proceeds rapidly.

Vaccination plays a crucial role in the prevention and reduction of the effects of serious conditions. Unfortunately, they are not entirely effective and could lose its effectiveness if the virus mutates.
Existing flu vaccines are valid for about one year and are 70% – 80% effective against transmission with strains of influenza virus that are identical to strains used in the production of vaccines.

The WHO believes that it is too early to tell how the A(H1N1) virus would change. It is closely monitoring any changes in the virus and this would help countries quickly react to any important changes that the virus may show.

Vaccines help the body combat certain diseases in case an individual becomes afflicted with the illness in the future. On the other hand, an antiviral drug is used on people who is already infected with a virus. Although they work in various ways, they generally work to prevent the virus from spreading to different cells in the body.

Swine flu vaccines are administered prior to exposure to a virus so they would be protected from that agent. Antivirals only work if administered within a certain period of time before or after they are exposed to the virus.

How To Keep Yourself from Being Infected With Swine Flu

How To Keep Yourself from Being Infected With Swine Flu

Swine flu is an illness which derives its name from a virus that infects pigs. While the virus cannot affect people, they are likely to get an infection from time to time. The virus is communicable and can be transmitted from one person to another.

The symptoms of swine flu are like those manifested in a regular flu and may include cough, sore throat, body aches, headache, fever, chills and fatigue.

The H1N1 virus continues to become widespread in the United States. The Center for Disease Control believes that the number of cases, hospitalizations, and deaths will continue within the coming days and weeks.

The Center for Disease Control is aggressively responding to the growing outbreak. The objective of the agency is to curb the spread and severity of the illness as well as to inform health care providers, public health officials, and the general public to fend off the challenge by the medical crisis. Likewise, the CDC is giving interim guidance on a daily basis as a response to the rapidly growing crisis.

For treating swine flu, there are antiviral medicines that can be administered. So far, oseltamivir, amantadine, rimantadine, and zanamivir are the approved drugs for swine influenza treatment in the United States.
However, amantadine and rimantadine will not work against swine flu as the H1N1 virus was found to be resistant against these medicines. Laboratory procedures, on the other hand, have proven that H1N1 is susceptible to oseltavimir and zanavimir.

Using antiviral drugs in the treatment of swine influenza works by making your illness milder and making you feel relieved earlier than expected. Aside from that, antiviral medicines prevent the onset of serious complications.

Antiviral medicines are most effective when administered after the onset of the illness usually within a couple of days. However, it should be considered two days after the onset of symptoms, especially for hospitalized patients or those at greater risk for influenza-related complications.

Administration of anti viral drugs is also useful in preventing influenza when given to an individual who is not sick but has exposed to a person with swine influenza.

It can reduce the possibility of infection by 70% to 90%. The duration of intake will be determined by the condition of the patient. Currently, there are no accessible vaccines for protecting against H1N1.

In order to keep yourself from getting infected by the virus, here are some of the things that can be done:

– Keep yourself informed about H1N1. You can visit the official website of the World Health Organization or check brochures from local hospitals or medical facilities.
– Since the influenza virus can be transmitted from one person to another through coughing or sneezing, you can keep yourself busy by doing the following:

– When coughing or sneezing, cover your nose and mouth with a tissue. After using the tissue, dispose of it and throw it in the trash.
– Wash your hands with soap and water after coughing and sneezing. Use alcohol-based hand sanitizers whenever necessary.
– To prevent germs from spreading, refrain from touching your eyes, mouth, or nose.
– If you become ill, the CDC recommends that you avoid contact with other people at work or school so as not to infect them.
– Comply with public health advice concerning school closures, crowd avoidance, and social distancing efforts.

As far as swine flu is concerned, health authorities are doing everything they can to prevent the outbreak of another deadly virus.

An Overview of Swine Flu

Swine flu or influenza is a condition caused by strains of subtypes of Influenza A virus called H1N1, H1N2, H3N1, H3N2, and H3N3. These viruses are common in pigs located in midwestern United States, Canada, South America, Mexico, Mainland China, Japan, Taiwan, Europe, and other Eastern Asian countries.

Transmission of influenza virus from swine to humans is relatively uncommon and does not always result to human influenza but often leads to production of antibodies in the blood. When properly cooked, pig meat does not have the potential of passing the virus. Transmission that leads to human influenza is called zoonotic swine flu.

People who work with pigs, particularly those with direct exposure, are at greater risk of being infected with swine flu. Towards the middle of the 20th century, identification of influenza subtypes became likely paving the way for an accurate diagnosis of transmission to humans. Since then, 50 infections have been confirmed and recorded.

It is rare for these strains of swine flu to be transmitted from one human to another. In humans, the symptoms of swine flu are similar to common influenza as well as influenza-like illness such as chills, sore throat, fever, coughing, muscular pains, severe headache, and general discomfort.
The 2009 swine flu outbreak in humans was caused by a new strain of influenza A virus subtype H1N1 which have genes that closely resemble swine influenza. The root of this new strain is not known. According to the World Health Organization for Animal Health, this new strain has not been isolated in pigs. It is capable of human-to-human transmission and manifests the normal symptoms of influenza.

Swine can be infected with human influenza such as the case of the 1918 flu pandemic and the 2009 flu outbreak. Swine flu was first proposed as a disease associated with humans during the 1918 flu pandemic. During that time, pigs became simultaneously sick with humans.

Influenza virus as a cause of disease in pigs was first identified in 1930. For the next six decades, strains of swine influenza became almost exclusively H1N1. From 1997 to 2002, new strains of three varied subtypes and 5 different genotypes were identified as the cause of influenza among pigs in North America.

From 1997-1998, H3N2 strains developed. They included genes acquired through reassortment of human, avian, and swine viruses and have been a principal cause of wine influenza in North America. Reassortment between H1N1 and H3N2 resulted to the development of H1N2. In Canada, a strain of H4N6 resulted from the reassortment of avian and swine flu but was isolated on a single farm.

The H1N1 variant of swine flu is one of the descendants of the strain that brought about the 1918 flu pandemic. While persisting in pigs, the descendants of the 1918 virus have also been transmitted throughout the 20th century which resulted to the usual seasonal influenza outbreaks.
It is interesting to note that direct infection from pigs to humans is rare, with only 12 confirmed cases in the United States since 2005.

However, since the influenza strains remain in the pigs after they have disappeared in the human population can make these pigs a reservoir where the influenza virus could survive and later on transmitted to humans as soon as their immunity to the strain is no longe effective.

Swine flu has been recorded as zoonosis in humans several times, oftentimes with limited distribution and rarely with massive distribution. Swine outbreaks are common and can lead to significant economic losses in the industry, mainly leading to stunting and expanded market time. Swine influneza, for instance, the British meat industry has experienced 65 million of losses annually.