Tag: Swine Flu Vaccine

Pregnant Women Are More Risky In Swine Flu

Some complications among pregnant women as the Swine Flu continue to spread across the country, and soon to the world, and that this high-risk group needs to take antivirals as soon as infection is suspected. Just like what happen to a pregnant woman in Texas who suffers and died of Swine Flu infection. Medical officials believe that pregnant women are at higher risk of complications of influenza, whether it’s the seasonal influenza or pandemics of the past.

The Centers for Disease Control and Prevention (CDC) investigates twenty cases of pregnant women with the swine flu, most of them experienced complications. Complications can include pneumonia, dehydration and premature birth. It is very important that doctors who are caring for pregnant women they suspect may have influenza, that they issue prompt treatment with antiviral medicines the Tamiflu and the Relenza. Doctors can be hesitant to take care of pregnant women with antiviral drugs and pregnant women may be disinclined to take them out of fear that they may pose a risk during pregnancy.

The benefits of using the antiviral drugs to treat influenza in a pregnant woman outweigh the theoretical concerns about the drugs strongly say by the medical experts who have looked into this situation. Of the three swine-flu related deaths in the United States, one involved a 33-year-old pregnant woman from Texas who had other health problems before she was infected with the virus.

From the undetermined source that only one out of three Americans would get Swine Flu vaccine. So, it means the vaccine manufacturers have no enough capability to do more drugs against the outbreak.
There are many people who become ill don’t seek medical attention and are never tested for this strain of flu especially if they only knew that they only have simple kind of flu.

In other news that weve read about the number of Swine Flu cases from hospital records doesnt match with the real numbers suspected because they declined to seek medical attention.

The report also suggested that the true number of largely unreported swine flu infections in Mexico, the outbreak’s epicenter, possibly had already reached 32,000 cases and approximately 1% of them are pregnant women too. The World Health Organization’s official tally for Mexico stood at 2,059 confirmed human infections, including 56 deaths.

The United States has now surpassed Mexico believed to be the source of the outbreak as the country most affected by the epidemic, according to WHO statistics. The agency reported that there are 6,497 confirmed cases of swine flu in 33 countries, with Canada, Spain and the United Kingdom having the most cases outside of the United States and Mexico.

In the meantime, back in Mexico, federal health officials said that the worst seemed to be over despite more deaths, toll rose to 58 deaths and 2,282 confirmed cases of swine flu a rise of two deaths and 223 more cases.

World Health Organization expert expressed support for the more selective use of antiviral medicines such as Tamiflu and Relenza against Swine Flu even though the pregnant women and the doctors of the pregnant women are declining the use of antiviral drugs. According to health officials that there are some European countries aggressively take antiviral drugs throughout their population to save themselves.

While countries like the United States and Mexico, they are trying to save their patients with underlying conditions and also the other groups at risk, such as pregnant women and be treated. Swiss drug maker Roche Holding AG offered a charitable work to donate some of their Tamiflu supplies to the WHO enough for nearly 6 million people.

In Dire Need of Swine Flu Vaccine

According to the World Health Organization, efforts for developing a swine flu vaccine has been ongoing since the first human case of the virus has been confirmed. Estimates place the initial doses of the vaccine will be administered in 5 to 6 months time.

While people diagnosed with H1N1 virus seems to be headed for recovery, there have been deaths recorded. Aside from that, receiving vaccines for this virus is important particularly the elderly and individuals with a weak immune system, since they are prone to complications such as pneumonia.

Likewise, the vaccine will serve as protection in case the condition persists particularly during the winter months which is the time when influenza is at its peak.

According to the World Health Organization (WHO), although they are still incomplete, current evidence shows that seasonal influenza vaccines will provide minimal or no protection against swine flu. Every year, a new batch of flu vaccine is developed and matched with strains that the WHO determines will most probably circulate in the winter months, which happens to be the peak season for influenza outbreaks.

Influenza virus comes in various strains which contains different proteins on their surfaces. The body’s immune system can only fight and destroy a virus if they are able to recognize these proteins. It is worth noting that antibodies that recognize one strain may not detect other strains.
Existing vaccines may only offer some protection against swine influenza if the proteins on its surface are identical to strains used to develop previous vaccines. According to the NIBSC, they are trying to determine if the swine flu virus, which is an H1N1 strain of type A influenza, as well as previous H1N1 vaccines match current vaccines.

The preparation of a vaccine commences after a virus develops as they provide the starting point for the production of the vaccine. As such, there is always a time delay while a vaccine is being developed. Preparation of a vaccine involves several steps so it would take several months before a vaccine becomes available.

According to WHO estimates, the virus needed for producing the vaccine will be accessible to vaccine manufacturers by the middle of May while the initial dose for a new vaccine would be ready within 5 to 6 months after that. Waiting time would be much longer if the growth of the vaccine proceeds rapidly.

Vaccination plays a crucial role in the prevention and reduction of the effects of serious conditions. Unfortunately, they are not entirely effective and could lose its effectiveness if the virus mutates.
Existing flu vaccines are valid for about one year and are 70% – 80% effective against transmission with strains of influenza virus that are identical to strains used in the production of vaccines.

The WHO believes that it is too early to tell how the A(H1N1) virus would change. It is closely monitoring any changes in the virus and this would help countries quickly react to any important changes that the virus may show.

Vaccines help the body combat certain diseases in case an individual becomes afflicted with the illness in the future. On the other hand, an antiviral drug is used on people who is already infected with a virus. Although they work in various ways, they generally work to prevent the virus from spreading to different cells in the body.

Swine flu vaccines are administered prior to exposure to a virus so they would be protected from that agent. Antivirals only work if administered within a certain period of time before or after they are exposed to the virus.

Vaccinations of Swine Flu

Vaccine against seasonal influenza strain H1N1 is not believed to protect us. Vaccines against the Swine Flu to cope with seasonal flu to minimize infection rates are typically developed, and yet annually it still kills around half a million of the worlds population. Today, they use an injection of “killed virus”, the worlds flu vaccines. Manufacturers are asked to produce a vaccine for H1N1, they are unlikely to be able to respond quickly enough if a global pandemic is declared.

About a billion doses of any one vaccine each year is the only they can produce, so that even if all the capacity was switched to fight a pandemic flu, as opposed to a seasonal flu. Few years ago, the supply of the vaccines they have produced were enough to epidemic but now is not enough for the total populations outbreak.

Deadlier wave of a new H1N1 strain they forecast will reappear this fall and they have to produce pandemic vaccines as early as now to prepare for a turn out as the vaccine may not be as effective will be sure to a big waste of resources with serious results, and there would also be a shortage of seasonal flu vaccine available. Only a few more weeks were needed for the World Health Organization (WHO) and Centers for Disease Control and Prevention) CDC to develop a “seed strain” of the pandemic virus on the first days May, but producers would then need four to six months before they could create large volumes of vaccine.

In other point of view, the WHO will attempt to make sure that a substantial amount is available and should a pandemic be declared and a vaccine produced, for the benefit of developing countries. Vaccine manufacturers and countries with standing orders, such as the U.S. and some European countries will be asked to share with developing countries from the moment the first batches are ready if an H1N1 vaccine is made.

2009-2010 flu seasons are ineffective against the new strain with the previous influenza vaccines for the north and south hemispheres. The WHO claims that two separate immunizations will be required for seasonal and swine flu, but no decision would be made on whether to begin producing a swine flu vaccine. The board will receive inputs from manufacturers (e.g. GlaxoSmithKline, Sanofi-Aventis, Novartis and Baxter International) regarding when they are able to finish manufacturing the seasonal shot and begin production of the swine flu vaccine, waiting from the WHO of their recommendations and “seed virus”, and some may be ready to proceed with production at that time.

There also antiviral drugs available for treatments of influenza, the virus is resistant to amantadine and rimantadine but sensitive to the oseltamivir and zanamivir. There remains concern that this strain may mutate develop resistance to oseltamivir in the future. For the treatment and prevention of the Swine Flu, the CDC recommended the use of Tamiflu (oseltamivir) and Relenza (zanamivir). Studies shows that the medication continues to maintain its effective that why the U.S. government had already extended the shelf life of federally stockpiled Tamiflu from their original five years to seven years.

Buying medications from online sources is not recommended by the WHO because they believed that half of the drugs they sold are counterfeited. Others are thinking if they grab up antiviral drugs for their safe even if they have no symptoms, the health officials warned them may eventually lead them to the Swine Flu virus developing drug resistance.

Swine Flu Vaccine Productions

To discuss and make strong decisions to fight the widespread Swine Flu, the World Health Organization set a meeting with the vaccine manufacturers together with other health experts to stop the Swine Flu Outbreak. Different Pharmaceutical companies are ready to begin making a Swine Flu vaccine but as the virus may alter, there are questions formed:

How much should they have to produce? How will the government distribute the vaccines to the infected areas? Who should get it, babies, youngsters, adults, men, women, pregnant?

Most flu vaccine companies mentioned that they can only make one vaccine at a time: either seasonal flu vaccine or pandemic vaccine. Production takes months and it is impossible to switch halfway through if health officials make a mistake. Vaccine makers can make limited amounts of both seasonal flu vaccine and pandemic vaccine though not at the same time but they cannot make massive quantities of both because that exceeds manufacturing capacity.

Even if we are in the modern era, still the health officials have a big problem to solve the spreading of deadly swine flu is, and whether they will need more seasonal flu vaccine or swine flu vaccine. Scientists are not sure the effectiveness of a vaccine, if the swine flu will transmute. Only two billion doses of swine flu vaccine could be produced annually based on the estimation of World Health Organization officials, though the first batches wouldn’t be available for four to six months.

A “seed stock” to make the vaccine, which should be ready and it will be distributed to manufacturers worldwide so they can start producing the vaccine is now on the go as the U.S. Centers for Disease Control and Prevention works on. After the vaccine manufacturers get the seed stock, they won’t know how many doses of vaccine they can make or how long that would take.

Including vaccine producer, GlaxoSmithKline PLC, the World Health Organization is under negotiation process to save some of their swine flu vaccine for poorer nations. A couple of years ago members of the rich nations like United States, Switzerland, France, Denmark, Canada and Britain signed deals with the vaccine makers to guarantee them pandemic vaccines as soon as they’re available.

Cipla (The pharmaceuticals giant in India) instructed by the World Health Organization to make a generic version of Tamiflu antiviral drug. Tamiflu also known as oseltamivir, one of the two antiviral drugs to treat the Swine Flu. Then WHO said Cipla’s generic version was more effective than the original made by Swiss firm Roche Holding AG and would hopefully make the drug more accessible to the third world countries. As we all know that Indian pharmaceuticals produce drugs in very affordable prices.

North America has been the hardest-hit continent for the Swine Flu virus that kills two Americans from Texas (including a pregnant woman) and one in Washington. If the vaccine productions are enough to all suspected Swine Flu carrier, it wont happen again that a simple pregnant woman died fighting the virus.

Through this article, we will inform the public of an early planning and prevention against Swine Flu for their safety. Consult to the Health Officers about planning and prevention against the virus. According to an unidentified source that one out of three Americans can only take the Tamiflu.