Tag: seizures

Drugs to Fight Alzheimer’s

Although there is no known cure yet for Alzheimer’s disease, there are already a number of drugs available worldwide that can help slow down a patient’s cognitive deterioration. The main aim of these Alzheimer’s medications is to try and improve cognitive ability or the person’s capability to think, perceive, judge and recognize.

There are currently five drugs approved by the Food and Drug Administration (FDA) that can be used to treat Alzheimer’s. There is ongoing research done all the time to test the effectiveness of such medications since they do not serve as a cure-all for the disease.
These medications may not have the same effects on all patients that are suffering from Alzheimer’s. But such prescription drugs can have significant effects on some of the patients with Alzheimer’s disease and should be given consideration as a possible treatment.

The 5 FDA Approved Medications are:
Aricept
Cognex
Exelon
Razadyne
Namenda

The first four drugs listed above belong to a group of drugs known as Cholinesterase Inhibitors. They work by trying to delay the break down of a substance known as acetylcholine in the brain which helps in bridging communication between nerve cells and has an important role in a person’s memory.

Nameda on the other hand acts on another neurotransmitter called glutamate and shields the brain from then said substance which contributes to the death of brain cells in people with Alzheimer’s disease. This drug is more effective in treating moderate to severe forms of Alzheimer’s disease, improving the day to day life of the person with Alzheimer’s disease.

The most common side effects associated with the drug Nameda include dizziness, confusion, constipation, headache and skin rashes. Some patients may experience less common side effects such as tiredness, back pain, high blood pressure, insomnia, hallucinations, vomiting and occasional shortness of breath.

The drugs Aricept, Exelon and Razadyne are seen to be most effective in treating the early stages of Alzheimer’s disease. This group of prescription drugs has been shown to have some modest effect in slowing down the degeneration of a patient’s cognitive abilities.

These drugs can also help in trying to reduce certain behavioral problems usually exhibited by people suffering from Alzheimer’s. When these drugs are administered effectively on an Alzheimer’s patient, they can significantly improve one’s quality of life and more able to cope up with the disease.

Alzheimer’s patients taking these medications may experience some side effects which may not be the same for all patients. Common side effects observed in patients using the drug Aricept include nausea, vomiting, excessive tiredness, sleeping troubles and muscle cramps.

Less frequent observed side effects of the drug are headaches and dizziness with rare cases of patients suffering from anorexia, gastric or duodenal ulcers, gastro-intestinal hemorrhage, bladder overflow obstruction, liver damage, convulsions, heart problems and psychiatric disturbances while using Aricept as medication.

The usual side effects seen in using Exelon as treatment for Alzheimer’s are nausea, vomiting, weight loss, stomach upset and fatigue. Less usual side effects observed with the use of the said drug are abdominal pain, sweating, diarrhea, headaches, tremor, and psychiatric disturbances such as anxiety or depression with rare cases of patients experiencing gastro-intestinal bleeding.

The drug Cognex is used less frequently for Alzheimer’s treatment as it can cause serious liver damage to most patients. Other side effects of the drug include nausea and vomiting. Some patients may also experience some abdominal pain, sore muscles, headache, dizziness, rapid breathing, increased urination, insomnia, runny nose or mouth, swelling in legs and feet when taking Cognex. Some of the most severe side effects associated with using Cornex are liver damage, heart problems and seizures.

The common side effects often reported with the use of Razadyne are nausea, vomiting, appetite loss and weight loss. Less common are fatigue, dizziness, tremor, headaches, abdominal pain, urinary tract infection, blood in urine, runny nose. There are no serious side effects with this drug.

Discovering Hyponatremia and Preventing It!

How many people really know without reaching for a dictionary what hyponatremia is? The bad news is that most people are unaware of what it is, yet it is a very dangerous condition that occurs quite often. Much more often than it really should in fact. To blame for the heightened occurrences is the fact that most people do not understand the proper fluid levels that should be maintained during exercise. This is particularly important during those exercises that are quite intensive such as marathons and endurance activities.

Hyponatremia is so important because it involves the blood sodium levels in the body. It is important that these levels be maintained in a proper proportion in order for the body to remain healthy. If the levels are adjusted through extreme sweating or even an over abundance of water consumption then Hyponatremia can occur which creates several problems. If you are seeing a sports medicine doctor and discussing participating in an endurance activity be sure to thoroughly ask about hyponatremia so that you can avoid it as much as possible.

Hyponatremia is important because it occurs when sodium levels are greatly decreased. This occurs in the normal process of sweating. However, creating the actual problem is when athletes consume large amounts of water continuously, which further reduces the ratio of the blood sodium levels. This lowered ratio is what creates the problems of hyponatremia. However, the solution is sometimes quite easy, but unless you have discussed the problem with your doctor, you are unlikely to know.

Symptoms of hyponatremia are as subtle as a nauseated feeling, some small muscle cramps, possibly being disoriented and even a bit confused mentally. This is quite often mistaken for just simply being dehydrated which will prompt many people to reach for more water to drink, which ultimately makes the problem much worse. Extreme cases of hyponatremia include symptoms such as comas, seizures and in the most extreme cases, death is possible.

In order to really prevent and treat hyponatremia it is vital that you drink a sports drink that contains sodium, or else eat a food with sodium especially higher levels of sodium to quickly restore the proper levels to the body. In addition, cutting back on the plain water consumption until sodium levels are higher is also advised. If you are having severe symptoms, it is best to see a doctor immediately, preferably a sports medicine doctor who is knowledgeable about treatment options.

In order to prevent hyponatremia there are a few things that you can easily do. The first is ensuring that you are keeping a sports energy drink on hand to continuously drink. While drinking water is important as well, the sports energy drink will help replenish sodium levels while the water will flush more sodium from the body.
If you do not have hypertension discuss with your doctor increasing your sodium intake levels for a few days before the endurance event. Only increase your sodium levels under the watchful eye of your doctor or you could create problems with hypertension where none previously existed.

Additionally, it is best to always drink plenty of fluids. The best guideline to use is a cup of fluids, which is 8 ounces for each 20 minutes of activity. If you are engaging in an hour-long endurance activity that would translate into 3 cups of fluids.

Additionally, it is best to only replace fluids that you lose. This means that you should avoid adding additional fluids to your body that are not needed. For example if you lose 2 pounds from fluid loss, you should replace the fluids that were lost. This would not mean drinking more than 4 cups of fluids at a maximum to replace the missing fluids.

With proper precautions, you can avoid having a problem with hyponatremia and instead enjoy participating safely in the endurance activity of your choice. With careful medical treatment and proper prevention, it is not a problem that will force you to stop engaging in sports; rather it can make you more aware of your bodies nutritional requirements.

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