The Phases of Swine Flu

A process that happens if two different types of influenza virus infected a single cell and it can produce a new strain of influenza is called re-assortment. It will act as a “mixing vessel” in which re-assortment can occur between flu viruses of several species such as pigs are prone to influenza viruses that can also infect both humans and birds. This is because if the virus allows pieces of RNA from different viruses to mix together and form a novel type of virus as a new virus particles are being assembled from a virus splitting between eight independent pieces of RNA.

On the other hand, the World Health Organization raised the pandemic alert level from phase four to phase five, signaling that a pandemic is “imminent”.

To know more about different phases of Swine Flu as defined by the WHO, I enlisted six of them” defined by the WHO:

If a virus circulated among animals but there are no reported cases of infections to humans will fall under phase one. An example of this phase is an outbreak of flu symptoms in your hog race backyard.
In phase two there is an identified animal flu virus and caused infections to human, and it will be considered a potential pandemic threat.

An example is when the owner either the child or an adult within the hog race backyard got infected with a flu from their animal symptoms.
Phase 3 specified that a confirmed animal or human-animal flu virus has caused small outbreaks in human race, but has not resulted in human-to-human transmission that is sufficient to sustain community-level outbreaks. An example in this phase is when a child within the hog race backyard got infected together with his father, his mother and his siblings.

Radically in Phase 4, there is a cause of community-level outbreaks of human-to-human transmission of an animal or human-animal flu virus. This phase will focus to contain the spreading of the virus. The United Nations will then inform different countries asking to advice their people such as traveling to containment areas. All countries with infected with the swine flu must also consider in deploying a pandemic vaccine. An example of this when the infected family member went out from their backyard decided to talk to his friends and unaware that hes spreading the virus.

In the 5th phase, if there are at least two countries in one region and spread the virus by means of human-to-human transmission. The signal of the pandemic is imminently strong. The infected countries are required to advise people with respiratory illnesses to stay home. There should be an advisory of suspension of classes. An example of this is when a man-infected virus either a family member or any of his friends travel to another neighboring country.

The sixth and final phase also called the pandemic phase. A pandemic phase is just like a spread of virus in phase 5 but extended at least one other country outside their geographic region. There must be an implementation of contingency plans of health systems in all levels. An example of this is when a man-infected virus travel to another continent.

Whatever phases of Swine Flu outbreak, we are experiencing in our country or geographic region we must prepare and prevent it to spread to lessen the death toll.

The Lowdown on The 2009 Swine Flu Outbreak

The 2009 outbreak of swine flu or H1N1 virus is recently hugging the limelight due to the potential harm or effects it can have on a patient or on a community. Unfortunately, the source of the virus still cannot be traced.

Before the first case in the United States was discovered, the illness was believed to have started in Mexico which eventually spread to other countries. Recently, the first case of swine flu was reported in
Costa Rica. Alarmed that it could grow into a worldwide flu epidemic, the World Health Organization of the United Nations and the Center for Disease Control Prevention (CDC) in the United States raised its pandemic alert level to Phase 5, which signifies that a “pandemic is imminent.”
While experts believed that the recent outbreak is not as fatal as previous epidemics, such as the SARS virus, health officials believe that the number of cases could go up as the new flu is expected to make its way throughout the United States.

The new swine influenza strain is apparently a new variant of four strains of influenza A virus subtype H1N1. According to the Center for Disease Control and Prevention, one of the strain is endemic in humans and birds and a couple are endemic in pigs.

However, according to scientists the 2009 H1N1 outbreak is of swine origin which is associated with the virus isolated in North America in 1998. To hasten understanding of the current outbreak as well as in coming up with a vaccine, scientists from Canada have completed the full genetic sequencing of the H1N1 virus.

The new strain of H1N1 has become widespread in Mexico and the United States with confirmed cases in 18 countries and suspected cases in 42 others. Travelers have been warned not to travel to affected countries such as Iceland, Singapore, Thailand, South Korea, Hong Kong, Singapore, to name a few.

In addition, warnings have also been issued warnings to visitors of countries affected by the outbreak. It is advisable for visitors to see the doctor right away if they experience flu-like symptoms.
In Mexico, schools, universities, and all public events were suspended from April 24 to May 6, 2009. In the United States, over 400 schools were closed as of May 3, 2009, which included schools in Texas and about 250,000 confirmed or probable cases.

Dr. Keiji Fukuda, who is the Assistant Director-General for Health Securiy and Environment of the World Health Organization confirmed that efforts to control the outbreak is already too late and should now focus on lessening the effects of the virus. He also clarified that closing borders or limiting travel to infected areas will do little in stopping the spread of the H1N1 virus.

On April 28, 2009, the Center for Disease Control and Prevention suggested that as much as possible, people should avoid non-important travel to Mexico.

According to Dr. Ira Longini, who is an expert in the mathematics and statistics of epidemics, staying at home, seeking medical care, closing public venues, and making anti-flu medicines accessible can help reduce the sickness by almost two-thirds.

Finally, according to Dr. Longini, the focus of efforts is to slow transmission until there is a vaccine that can be developed and made available for controlling swine flu outbreaks.

Swine Flu Vaccine Productions

To discuss and make strong decisions to fight the widespread Swine Flu, the World Health Organization set a meeting with the vaccine manufacturers together with other health experts to stop the Swine Flu Outbreak. Different Pharmaceutical companies are ready to begin making a Swine Flu vaccine but as the virus may alter, there are questions formed:

How much should they have to produce? How will the government distribute the vaccines to the infected areas? Who should get it, babies, youngsters, adults, men, women, pregnant?

Most flu vaccine companies mentioned that they can only make one vaccine at a time: either seasonal flu vaccine or pandemic vaccine. Production takes months and it is impossible to switch halfway through if health officials make a mistake. Vaccine makers can make limited amounts of both seasonal flu vaccine and pandemic vaccine though not at the same time but they cannot make massive quantities of both because that exceeds manufacturing capacity.

Even if we are in the modern era, still the health officials have a big problem to solve the spreading of deadly swine flu is, and whether they will need more seasonal flu vaccine or swine flu vaccine. Scientists are not sure the effectiveness of a vaccine, if the swine flu will transmute. Only two billion doses of swine flu vaccine could be produced annually based on the estimation of World Health Organization officials, though the first batches wouldn’t be available for four to six months.

A “seed stock” to make the vaccine, which should be ready and it will be distributed to manufacturers worldwide so they can start producing the vaccine is now on the go as the U.S. Centers for Disease Control and Prevention works on. After the vaccine manufacturers get the seed stock, they won’t know how many doses of vaccine they can make or how long that would take.

Including vaccine producer, GlaxoSmithKline PLC, the World Health Organization is under negotiation process to save some of their swine flu vaccine for poorer nations. A couple of years ago members of the rich nations like United States, Switzerland, France, Denmark, Canada and Britain signed deals with the vaccine makers to guarantee them pandemic vaccines as soon as they’re available.

Cipla (The pharmaceuticals giant in India) instructed by the World Health Organization to make a generic version of Tamiflu antiviral drug. Tamiflu also known as oseltamivir, one of the two antiviral drugs to treat the Swine Flu. Then WHO said Cipla’s generic version was more effective than the original made by Swiss firm Roche Holding AG and would hopefully make the drug more accessible to the third world countries. As we all know that Indian pharmaceuticals produce drugs in very affordable prices.

North America has been the hardest-hit continent for the Swine Flu virus that kills two Americans from Texas (including a pregnant woman) and one in Washington. If the vaccine productions are enough to all suspected Swine Flu carrier, it wont happen again that a simple pregnant woman died fighting the virus.

Through this article, we will inform the public of an early planning and prevention against Swine Flu for their safety. Consult to the Health Officers about planning and prevention against the virus. According to an unidentified source that one out of three Americans can only take the Tamiflu.