Rheumatoid Arthritis

Rheumatoid Arthritis
Charlene J. Nuble

A shooting pain in the knee. A burning sensation in the hand. Before you know it, you have rheumatoid arthritis. Rheumatoid arthritis is a chronic inflammation of the joints. Rheumatoid arthritis is an autoimmune disease in which the immune system attacks normal tissues as if they were invading antibodies. Rheumatoid arthritis also causes inflammation of the tissues around the joints and other organs of the body. The hands and feet are the most affected areas of rheumatoid arthritis although it can also affect any joint lined by a membrane. Rheumatoid arthritis is referred to as a systematic illness and sometimes called rheumatoid disease.Rheumatoid arthritis manifests itself over a period of a few months. However, for some, the disease appears overnight. Accelerated onset of rheumatoid arthritis does not mean the individual is at greater risk of the progression of the disease. Rheumatoid arthritis can lasts for years without symptoms. But rheumatoid arthritis is an illness that progresses and has the potential to cause joint destrution and functional disability. Usually, patients suffer cycles from severe to light symptoms. In terms of statistics, rheumatoid arthritis is three times more common in women than in men. It also besets people of all races equally. Rheumatoid arthritis can begin at any age but most often start in the early forties. What causes rheumatoid arthritis? The truth is, its cause is still unknown. Viruses, bacteria, and fungi have long been suspected but none has been proven to be the cause. The cause of rheumatoid arthritis has been the focus of different research activities. There are some scientists who believe that the tendency to develop rheumatoid arthritis may be genetically inherited while others believe that certain factors in the environment might elicit the immune system to attack the body’s own tissue components. This attack results to the inflammation in various organs such as lungs or eyes. Researchers have also found that environmental factors may also play a role in the cause of rheumatoid arthritis. In fact, scientists reported that smoking tobacco increases risk in the development of rheumatoid arthritis.The symptoms of rheumatoid arthritis depend on the degree of tissue inflammation. Rheumatoid arthritis is said to be active if the body tissues are inflammed. When the tissue inflammation subsides, rheumatoid arthritis is said to be in remission. Remissions may happen spontaneously or with treatment and can last for weeks, months, even years. During active rheumatoid arthritis, symptoms are felt. Symptoms may include fatigue, lack of appetite, low grade fever, and muscles and joint aches. Muscles and joint stiffness are usually felt during mornings and after a period of inactivity. During relapses (from inactivity to activity) of rheumatoid arthritis, joints become red, swollen, painful, and tender. This happens because the tissue lining of the joints become inflamed which results in the excess production of joint fluids. Multiple joints are usually inflamed in symmetrical pattern and the joints of both hands and wrists are often affected. Simple tasks such as turning the door knob and opening the jars can be painful. Rheumatoid arthritis can also affect the joint responsible for the tightening of vocal cords to change the tone of the voice although rarely. But when this happens, it can cause hoarseness of the voice. As mentioned before, rheumatoid arthritis is a systematic disease which can affect organs and areas of the body other than the joints. Sjorgen’s syndrome is the inflammation of the glands of the eyes and mouth which causes dryness. Rheumatoid inflammation of the lung lining can cause chest pains because the lung tissue itself is inflamed and nodules of inflammation also develop within the lungs. Rheumatoid arthritis can also reduce the number of red blood cells which can result to anemia and white blood cells which can result to increase risk of infections. A rare, serious complication of rheumatoid arthritis is blood vessel inflammation which can impair blood supply to tissues and lead to death of tissues. A rheumatologist is a doctor who specializes in arthritis and other related diseases. The rheumatologist reviews the history of symptoms, examines the joints, and the other parts of the body for the inflammation. The diagnosis is usually based on the pattern of symptoms, the distribution of the inflamed joints, and the blood and x-rays obtained. Until now, there is no known cure for rheumatoid arthritis. Reducing joint inflammation and pain, maximizing joint function, and preventing joint destruction is the current goal in treating rheumatoid arthritis. Early medical intervention has been found to improve outcomes in treatment. Optimal treatment includes combination of medications, joint strengthening exercises, joint protection, and patient education. Treatment is customized according to many factors such as disease activity, types of joints involved, general health, age, and occupation. But treatment is most successful when there is close cooperation between the doctor and the patient.————————-Note: This article may be freely reproduced as long as the AUTHOR’S resource box at the bottom of this article is included and and all links must be Active/Linkable with no syntax changes.————————- About the Author
Charlene J. Nuble 2005. For up to date links and information about arthritis, please go to: http://arthritis.besthealthlink.net/ or for updated links and information on all health related topics, go to: http://www.besthealthlink.net/

Knowing Your Cancer, How Lymphoma Spreads

The following article lists some simple, informative tips that will help you have a better experience with Lymphoma.

These are some facts according to the Leukemia & Lymphoma Society: 19. 5 out of every 100, 000 people in the world fashion Non – Hodgkins Lymphoma while 2. 8 out of every 100, 000 people in the world are diagnosed with Hodgkins disease. Hodgkins disease and Non – Hodgkins Lymphoma are two of the needed classifications of lymphoma, a cancer of the bodys lymph system. The lymph system, being part of our immune system, is tasked to eliminate bacteria, diseases and infection from our frame. But when the cells multiply abnormally, tumors begin to appear in the lymph nodes. You can feel these as lumps in the nodes of the neck, armpit and groin. Soon the cancer cells will spread in other parts of the build, how lymphoma spreads is a good thing to know.

Metastasis. This is a word we often hear in cancer patients. This is actually a term which refers to the spreading of cancer to the rest of the body. Lymphoma at first is a single tumor in one of the many lymph nodes of the body. What happens when the cancer cells cognize metastasis is that cancer – infected cells split today from the main tumor and moves to further part of the body. The cancer cells use the bloodstream to move from one area of the body to another. The cancer cell can attach itself to another lymph node or to other organs of the body. When it fastened firmly, the cells reproduce again until sensible creates another mass of tissue to form as a tumor. Then the full routine repeats itself.

For lymphoma, the cancer cells use the lymphatic system of the body to spread. The lymphatic construction of the body is pleasing much like the bloodstream, it is spread although out the body since it is responsible for keeping the habitus clean from infections and diseases. The lymphatic system is an open canal where cancer cells can travel and create more tumors.

The tumors are pretty deadly. Because of the accelerated rate of growth, these cancer cells can linger to make the tumors grow. Soon enough the tumors grow large enough that the healthy tissues or organs are prevented to function normally. Eventually the healthy tissues or organs commit halt functioning which spells death to the person.

Like any cancer, lymphoma has also a number of stages. These stages describe the severity of the condition and indicate how far the cancer cells have infected the body. Stage I is the first stage of the cancer. At this level, the cancer cells have only infected one lymph node or one part of the body. Because it is still developing, this stage is also referred to now the early disease.

The second stage or Stage II is far more alarming. At this point the cancer cells retain metastasis and have infected another one or even more lymph nodes or parts of the body. However, at Stage II the infection is limited to either above or below the persons diaphragm. This progression is called locally latest disease.

Stage III is known as the advanced disease. The cancer cells at this stage have found its way on both sides of the diaphragm and have established a number of tumors in those areas. The final stage or Stage IV or widespread disease is described by spread of the cancer cells to one or more of the bodys organs such as the bone, skin, liver or lungs.

This is how lymphoma spreads. That is why it is important for an early detection of the disease for proper and effective treatment.
Don’t limit yourself by refusing to learn the details about Lymphoma. The more you know, the easier it will be to focus on what’s important.

Knowing Your Cancer, Hodgkins disease

You should be able to find several indispensable facts about Lymphoma in the following paragraphs. If there’s at least one fact you didn’t know before, imagine the difference it might make.

Hodgkin’s lymphoma or otherwise proclaimed as Hodgkin’s disease is one of two kinds of lymphoma or a cancer of the lymphatic system. Thomas Hodgkin was the first person who published documented studies of the disease hence the cancer was named after him. Hodgkin’s lymphoma is different from the other benevolent of lymphoma chiefly through the presence of Reed – Sternberg cells in the cancer cells. These Reed – Sternberg cells burden perform seen through an open biopsy. In contrast, cells seen on non – Hodgkins lymphomas are mutated B – cells or T – cells.

It has been observed that Hodgkins lymphoma oftentimes begin to develop in the lymph nodes in the neck. This is again quite different from non – Hodgkins lymphoma which beings in different locations in the frame. Nonetheless, since this is cancer were talking about, from the neck lymph node spreading to other lymph node groups, the lungs, spleen, and bone marrow is one shot natural and inevitable if no treatment is undergone. It seems and that Hodgkin’s lymphoma targets the immediate nearby lymphatic regions before leaving eventually the lymphatic system and spreading throughout other organs of the body.

According to studies, Hodgkins lymphoma is more likely to develop in young adolescents particularly those within the age range of 15 to 24 as well as those who are more than 60 dotage aged. Besides this is totally colorful from non – Hodgkins lymphoma which rarely happens in young people and instead is more common to people tired 60 years old and above.

In determining a diagnosis, one can actually self – diagnose at least initially. A doctors expertise is still needed, of course, for a more accurate diagnosis of the disease. The symptoms that posses been reported are not that different from the antithetic kinds of lymphoma. The presence of a painless lump in the lymph nodes in the neck, underarm, or groin, recurrent fevers, unexplained qualification termination, night sweats and fanatical skins are among the warning signals of developing lymphoma.

Among the usual tests your doctors would require you to undertake includes glowing tests to check abnormalities in the blood counts, blood assembling, and abnormal erythrocyte sedimentation rate ( ESR ), X – rays to look at the lymph nodes, computerized tomography or CT scan and enterprising resonance imaging or MRI scans of the chest, pelvis, and abdomen to see if the cancer has already spread to other parts of the body.

Other scans that could be used to properly diagnose and determine the stage of the cancer are the positron emission tomography or PET scan which scans the cancer at a cellular level and the gallium scan which looks for radioactive intake of gallium which can mean the onset of the disease. There are other tests and procedures which doctors might conduct on you all in the aid of a opportune and accurate diagnosis.

Hodgkins lymphoma has several sub – types, namely nodular sclerosis ( NS ) which hits the lower neck, chest and collarbone, lymphocyte predominance ( LP ) which is made of malignant L&H cells which have a ” popcorn “, mixed cellularity ( MC ) which has lymph nodes that are usually contain Reed – Sternberg cells and inflammatory cells, lymphocyte depleted ( LD ), and nodular lymphocyte crack ( NLP ).

As they say, knowing is half the battle. Knowing more about Hodgkins disease is a good thing. You can contribute fully to the decision making process if you know precisely the situation you are in.
As your knowledge about Lymphoma continues to grow, you will begin to see how Lymphoma fits into the overall scheme of things. Knowing how something relates to the rest of the world is important too.

The Types of Non – Hodgkins Lymphoma

The more you understand about any subject, the more interesting it becomes. As you read this article you’ll find that the subject of Lymphoma is certainly no exception.

Lymphomas are cancers of the lymph system which ironically is part of the bodys defense mechanism to fight off infections and diseases. But sometimes the abnormal growth of the healthy lymphatic cells causes the tissues to mass up creating tumors and eventually becoming cancer cells. If left untreated, the cancer cells can soft break away from the tissues and begin infecting other parts of the lymphatic system and eventually moving to other organs of the body. There are essentially two kinds of lymphomas, the Hodgkins lymphoma and non – Hodgkins lymphoma.

Hodgkins lymphoma is characterized by the presence of Reed – Sternberg cells. Other lymphomas do not contain these cells so the rest of the lymphomas were classified as non – Hodgkin’s lymphoma or NHL. There are a number of sub – types of non – Hodgkin’s lymphoma. Each are quite distinct targeting specific age groups aside from having unique forms.

One kind of NHL is the lymphoblastic lymphoma or LBL which commonly occurs in children. In fact about 30 % of documented cases of lymphomas in descendants have been classified as lymphoblastic lymphomas. LBL is very aggressive kind of NHL and has caused quite a number of deaths in the past. But because of modern medicine and treatment techniques, LBL patients have better odds of surviving the countdown.

Unlike LBL, the diffuse histiocytic lymphoma type or DHL is a slow growing cancer. And because it is slow – growing the cancer is quite hard to detect. Also, slick are times footing the cancer reappears after treatment.

Another kind of NHL appears closer to the bodys surface. The cutaneous T – cell lymphoma or CTLC is a kind of lymphoma that affects the skin. What happens is that the white blood cells of the skin become cancerous. At first, the signs are dry, scaly skin with red or dark patches. These areas of the skin also itch a lot. But as the cancer cells continue to grow, the skin cede develop highly noticeable tumors. Eventually the cancer cells enter the blood dtreak and spreads all over the body which away infects other tissues and organs.

Although not common, the mantle cell lymphoma is another kind of non – Hodgkin’s lymphoma. This cancer borders on being rare since only an estimated 5 % of people diagnosed with NHL have it. It seems that the cancer is more likely to occur in masculinity 50 years old and older. The cancer starts off as a slow growing lymphoma but can suddenly become aggressive in later stages.

Doctors have made 4 classifications or stages of non – Hodgkin’s lymphoma which basically indicates how fast and how far the cancer cells have spread. Transaction 1 is when the cancer cells are grouped in lymph node or organ of the body. In stage 2 the cancer has spread to two or more groups of lymph nodes or organs on the same side of your diaphragm. Stage 3 is where the cancer cells have infected organs on both sides of the diaphragm and finally stage 4 is when the different types of non – Hodgkins lymphoma have gone beyond the lymphatic system and infecting other organs like the liver, bones, and lungs.
Hopefully the sections above have contributed to your understanding of Lymphoma. Share your new understanding about Lymphoma with others. They’ll thank you for it.