Tag: Naproxen

Aleve, Vioxx, Celebrex, and Bextra: What You Need to Know

Aleve, Vioxx, Celebrex, and Bextra: What You Need to Know About Arthritis Pain Medications
R.L. Fielding

Aleve, Vioxx, Celebrex and Bextra:What You Need To Know About Arthritis Pain MedicationsRecent controversy about the safety of pain medications for arthritis has left patients and health care professionals alike confused about which medications are safe to use. In fact, a recent survey by the Boston-based Rippe Lifestyle Institute indicated that many people with arthritis are suffering unnecessarily because they have stopped or reduced their use of pain relievers due to confusion about which drugs are considered safe.The survey also showed that now, more than ever, those with arthritis need to understand the benefits and possible side effects associated with all arthritis pain medications. In order to do so, people with arthritis, their caregivers and families must be familiar with recent news about the two types of drugs most commonly used to treat arthritis pain non-selective, non-steroidal anti-inflammatory drugs (NSAIDs), and another group of NSAIDs known as cyclooxygenase-2 (COX-2) specific inhibitors. COX-2 specific inhibitors vs. Other NSAIDsCOX-2 specific inhibitors are the newest members of the NSAID class of medications. Available by prescription only, they became widely used in recent years to reduce joint pain and swelling. COX-2 specific inhibitors work by selectively blocking, or inhibiting, one of the two enzymes associated with inflammation. Some experts think that this selective inhibition may be one reason for some of the negative side effects currently associated with COX-2 specific inhibitors.Non-selective NSAIDs were developed earlier than COX-2 specific inhibitors and have been widely used to relieve arthritis pain and inflammation for many years. Unlike COX-2 specific inhibitors, non-selective NSAIDs inhibit both major enzymes involved in the inflammatory process, COX-1 and COX-2. The non-selective NSAID category includes a number of different medications that are available in both prescription and over-the-counter (OTC) products.Timeline of EventsTo understand the current state of affairs, it is important to understand the sequence of events. The controversy started when a study published in the October 21, 2004, issue of the New England Journal of Medicine cited the COX-2 specific inhibitor, Vioxx as potentially causing major adverse events, including heart attack and stroke, among patients taking the drug. As a result, Merck (the drugs manufacturer) voluntarily withdrew Vioxx from the market. However, in the months following, the safety of the other available COX-2 specific inhibitors such as Celebrex and Bextra, as well as other arthritis pain medications in the non-steroidal anti-inflammatory (NSAID) class, were also called into question.Consequently, in February 2005, the US Food and Drug Administration (FDA) convened a special Advisory Committee, made up of members of the Arthritis and Drug Safety Advisory Committees, to review the cardiovascular safety of these arthritis pain medications.FDA Directive: Stronger Warning Labels for Some Pain MedicationsOn April 7, 2005, taking into account the recommendations of the Advisory Committee, the FDA issued the following directives: Bextra, a COX-2 specific inhibitor manufactured by Pfizer, was withdrawn from the market.All prescription NSAIDs must revise their labeling to include a black box warning that highlights the potential increased risk for cardiovascular (CV) events as well as the potentially life threatening gastrointestinal (GI) bleeding associated with these drugs. Celebrex, the only COX-2 specific inhibitor remaining on the US market, was included in this directive.All OTC NSAIDs (except aspirin) will be required to revise their labeling to include more specific information about the potential for GI and CV side effects, a stronger reminder to follow label instructions, as well as a warning about potential skin reactions.To further evaluate the potential for increased CV risk, the FDA also announced that all NSAIDs must conduct and submit to the FDA a comprehensive review and analysis of pertinent safety data from clinical trials. Aleve (naproxen sodium) is supported by clinical studies conducted to gain approval of naproxen as a prescription product and as OTC that do not provide any evidence of increased risk of cardiovascular events. Treatment Options: What Should Arthritis Patients Know?For some people who suffer from pain associated with arthritis, their symptoms can be managed with exercise, heat/cold therapy, joint protection, assistive devices, weight control, or in some severe cases, surgery. For others, medications are needed to help manage the symptoms associated with arthritis. When taken as directed OTC medications such as Aleve provide a safe and effective way to treat mild to moderate pain of minor arthritis. If patients have questions, they should consult their health care professional about which treatment option is most appropriate.Why Its Important to Treat ArthritisArthritis affects approximately 66 million Americans and is the nations leading cause of disability. There are over 100 different types of arthritis, and they all have different symptoms that vary in severity from person to person. The most common form of arthritis, osteoarthritis, is characterized by the breakdown of cartilage that causes the bones to rub together, resulting in pain, loss of movements and stiffness . Arthritis is usually a chronic condition. For more information on Aleve and naproxen, visit the Aleve website at www.aleve.com. For more information on arthritis pain relief, visit www.arthritis.org. About the Author
R.L. Fielding writes on a number of subjects.

Few Things to Consider When Seeking Lower Back Pain Relief

Few Things to Consider When Seeking Lower Back Pain Relief

The best thing that you may probably have considered in your search for an efficient lower back pain relief is to find out what really cause this condition. There are quite a number of factors that may result to lower back pain though there are conditions for which the causes are unknown. Nonetheless, the pain is real and sometimes excruciating.

Among these factors are muscle spasm, muscle strain, ligament sprains, joint problems, herniated disc, improper posture, too much weight carried by the lumbar section of the back bone and several more others.

A herniated disc, or sometimes called as degenerated disc is caused by the bulging between the bones. This condition may press on the nerves and cause the excruciating pain. However, many people don’t know what affected their back bones that induced this pain.

To allow lower back pain relief, there were different exercises and body positions, which may help raise the possibility of releasing the back bone from too much stress. Most physical therapists would suggest that the patient lie on the floor with pillows underneath his head and knees. It is important that the hips and knees are bent in this posture. This will help free the back from the weight and stress it is carrying.

If your case is severe, you may need to rest in this position for one to two days. However, you may need to reinforce your muscle strength during this period through walking, though this may hurt quite a bit.

If you would not want to risk muscle strength in this or the idea of walking while your lower back aches, you can use heating pads, ice packs and massages as alternatives. Their effects may be impermanent but temporary treatment may as well prove a great relief.

Nonprescription drugs may also be excellent aids for reducing pain and swelling. These include the following: aspirin, naproxen (Aleve), acetaminophen (Tylenol), ibuprofen (brand name: Motrin) and ketoprofen (Orudis).

Lower back pain may either be a continuous process or may be a series of attacks. For ongoing back pain, the ideal action to take is direct the treatment at the actual causes. This may mean loosing weight. Obesity is pointed as one reason why people suffer lower back pain. As we know, the lower back carries all the weight that may be induced on the upper body. Once the body is overweight and too much force is created to stress out the muscles and the bones on the lower back, the end result may be extreme lower back pain. Two other things that you might want to consider is to correct your posture and to put your muscles in shape.

These things, if addressed correctly may prove beneficial in searching for lower back pain relief

Advanced Medications for Back Pain Treatment

Fortunately for most patients, the present medicines, option treatments and therapies available work well. But just as each person has individual sets of symptoms and conditions, not all treatment options may be appropriate. Now if you are a back pain patient, it is best to seek medical help to customize a treatment plan that would work best for your case.

Discussed in the following section of this article are the available back pain treatment medications. Though it must be understood that they apply differently and may have varying effects.

Drug therapies
Today’s patients have a wide spectrum of medication choices to treat their persisting back pains. Some drugs are especially designed to treat certain conditions only but many are rather so versatile that their use may apply even for releasing muscle tension, inflammation and treat spasm. Yet, as unfortunate as any treatments may be, there are medications that may have extreme side effects. It is wise that you first discuss with your doctors the medications you will take and the plans to conquer or even minimize the side effects.

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
This type of medications often consist of aspirin, Naproxen, ibuprofen, Ketoprofen and a lot more others. These anti-inflammatory drugs often induce healing from back pain and reduce inflammation and swelling. When used on minimal doses, NSAIDs may act as mild analgesics but larger doses may bring the effects of genuine anti-inflammatory drugs. The most common side effects of conventional Non-Steroidal Anti-Inflammatory Drugs are gastrointestinal conditions. However with the newer released items for NSAIDs (e.g. COX-2 Inhibitors), patients may be allowed to take higher doses without the accompanying risks of side effects.

Acetaminophen
Acetaminophen such as Anacin-3, Valadol, Phenaphen, and Tylenol, are commonly known to have the effects of ordinary analgesics- the typical alternatives to NSAIDs. Analgesics medications are employed for acute pain treatment. However, on some special instances these may also be used as treatments for chronic pains.

Opiods
Because of their addictive nature, Opiods are rarely used as treatment for back pain but if so, only for the most severe cases that needs immediate, quick pain relief. These medications are generally not prescribed and many physicians refute that they may do more harm than good. Opiods include codeine and morphine, meperidine (Demerol), Oxycontin.

Muscle Relaxants
Muscle Relaxants are known to induce the efficiency created in most Non-Steroidal Anti-Inflammatory Drugs and are often prescribed only for severe back pains. These include medications such as cyclobenzaprine (Flexeril), methocarbamol (Robaxin), carisoprodol (Soma), and diazepam (Valium).

In order for these medications to work at their optimum, guidelines for using them must be followed and the doctor’s advises are the only things that may help you best aside from other medical assistance.