Tag: Metabolite

New Research Links Causes Of Hair Loss To Nutritional Deficiency

New Research Links Causes Of Hair Loss To Nutritional Deficiency

Whilst it may be comforting to know that humans are not alone in suffering hair loss (primates such as monkeys also experience thinning on their head) – understanding the causes of hair loss means we can take proactive action. Even though genetics does play a part, new research has uncovered a nutritional deficiency link in both men and women. And other factors, such as stress, and poor hair care, are well within our capacity to change.

The genetic link in hair loss has been well studied. It is associated with male and female pattern hair loss, or alopecia. In these individuals there is an increased sensitivity to the sex hormone, DHT. DHT stands for dihydrotestosterone, and is a powerful metabolite of testosterone. It contributes to men’s unique gender characteristics, as well as facial and body hair, and the deepening of men’s voices at puberty.

DHT causes the growth cycle of hair follicles to shorten, which in turn reduces the size of the hair shaft. Increasingly narrower hair is grown, sometimes as fine as fluff, and in more extreme cases, there is complete hair loss in that area.

In women, estrogen usually counteracts the effects of testosterone. But when women go through menopause, or suffer hormonal imbalances, the reduction in estrogen can lead to female pattern baldness. Fortunately, this is not as drastic in its hair loss effects as male pattern baldness. Instead the hair tends to thin, and the crown parting becomes wider.

But a very interesting study by L’Oreal has linked an iron deficiency to hair loss, in both men and women. This was a placebo controlled, double blind study in which 13,000 healthy men and women took a supplement, and had the ferritin (iron) levels in their blood measured and cross referenced with information on their hair loss.

The results showed not only a link between hair loss and iron deficiency, but they were able to estimate the risk of hair loss in a certain level of iron deficiency. For example, women whose blood ferritin levels dropped from a normal 70g/l to 40g/l, had a 28% higher chance of severe hair loss. The post menopausal women in the study who had severe hair loss all had much lower levels of iron than the women who didn’t have severe hair loss.

The problem with iron supplementation, however, is that excess iron builds up in the body’s tissues and becomes toxic. It has been associated with an increased risk of developing chronic illnesses. Iron levels can be tested by a doctor, so if hair loss is a concern, its best to get your iron levels tested first before taking iron supplements.

Other potential causes of hair loss – or at least, contributing factors are stress and poor hair care practices. Not brushing hair regularly, or washing it regularly, can affect the normal hair growth cycle.

When hair that is naturally at the end of its life cycle is removed through brushing, it allows another hair to grow underneath it. Regular brushing naturally removes dead hair that is ready to fall out. Not removing that hair means new growth cannot occur, as the old hair smothers the new growth. Dirt and oil build up can have a similar effect, so its important to wash hair regularly.

Stress can affect the circulation of nutrients and oxygen to the scalp, by causing the muscles in the scalp to tighten. If this happens over a long period of time, premature hair loss can occur. This cause of hair loss is distinct from male pattern baldness (which is hormonal), but it can certainly exacerbate the condition. And stress reduction techniques are simple things that can be added to a daily routine, to prevent hair loss, and improve the overall quality of life.

References:

1. Nutraingredients

2. Wikipedia Health

Balding Solution for Men and Women

Androgenetic alopecia (male and female pattern balding) is by far the most common cause of hair loss amongst men and a serious problem for many women. There are three important components which are responsible for both female and male balding:

1. A genetic predisposition for balding to occur

2. Excessive presence of male hormones

3. Aging – enough time for the first two factors to occur

Both men and women produce male hormones that have a useful role to play in both sexes; but the fact that androgens occur in much higher concentrations in men explains why male pattern baldness is more common than the female balding.

DHT the root cause of hair loss

It is metabolism of male hormones (androgen/testosterone) which is main cause of hair loss and male and female pattern balding both in men and women.

The metabolism of androgen involves an enzyme called 5 alpha reductase which combines with the hormone (testosterone) and converts it to DHT (Dihydro-testosterone). DHT is a natural metabolite of our body.

The cause of male and female pattern balding

Some individuals, both men and women, are genetically pre-disposed to produce more DHT than the normal individuals. It is this accumulation of DHT and its effect on the cells inside the hair follicle and root which is one of the primary causes of male and female pattern balding.

When DHT gets into the hair follicle and root, especially a region called the dermal papilla, it changes the cell’ activity and prevents necessary proteins, vitamins and minerals from providing nourishment needed to sustain life in the hairs of those follicles. Consequently, hair follicles are reproduced at a much slower rate.

This shortens their growing stage (anagen phase) and or lengthens their resting stage (telogen phase) of the follicle. DHT also causes hair follicle to shrink and get progressively smaller and finer. This process is known as miniaturization and causes the hair to ultimately fall. DHT induced androgenetic aloepcia is responsible for 95% of all hair loss.

Blocking the synthesis of DHT at the molecular level forms the basis for the treatment of MPHL (male pattern hair loss) and FPHL (female pattern hair loss). There are many natural DHT blockers and a number of drugs which are used for medical hair restoration.