An Overview of Swine Flu

Swine flu or influenza is a condition caused by strains of subtypes of Influenza A virus called H1N1, H1N2, H3N1, H3N2, and H3N3. These viruses are common in pigs located in midwestern United States, Canada, South America, Mexico, Mainland China, Japan, Taiwan, Europe, and other Eastern Asian countries.

Transmission of influenza virus from swine to humans is relatively uncommon and does not always result to human influenza but often leads to production of antibodies in the blood. When properly cooked, pig meat does not have the potential of passing the virus. Transmission that leads to human influenza is called zoonotic swine flu.

People who work with pigs, particularly those with direct exposure, are at greater risk of being infected with swine flu. Towards the middle of the 20th century, identification of influenza subtypes became likely paving the way for an accurate diagnosis of transmission to humans. Since then, 50 infections have been confirmed and recorded.

It is rare for these strains of swine flu to be transmitted from one human to another. In humans, the symptoms of swine flu are similar to common influenza as well as influenza-like illness such as chills, sore throat, fever, coughing, muscular pains, severe headache, and general discomfort.
The 2009 swine flu outbreak in humans was caused by a new strain of influenza A virus subtype H1N1 which have genes that closely resemble swine influenza. The root of this new strain is not known. According to the World Health Organization for Animal Health, this new strain has not been isolated in pigs. It is capable of human-to-human transmission and manifests the normal symptoms of influenza.

Swine can be infected with human influenza such as the case of the 1918 flu pandemic and the 2009 flu outbreak. Swine flu was first proposed as a disease associated with humans during the 1918 flu pandemic. During that time, pigs became simultaneously sick with humans.

Influenza virus as a cause of disease in pigs was first identified in 1930. For the next six decades, strains of swine influenza became almost exclusively H1N1. From 1997 to 2002, new strains of three varied subtypes and 5 different genotypes were identified as the cause of influenza among pigs in North America.

From 1997-1998, H3N2 strains developed. They included genes acquired through reassortment of human, avian, and swine viruses and have been a principal cause of wine influenza in North America. Reassortment between H1N1 and H3N2 resulted to the development of H1N2. In Canada, a strain of H4N6 resulted from the reassortment of avian and swine flu but was isolated on a single farm.

The H1N1 variant of swine flu is one of the descendants of the strain that brought about the 1918 flu pandemic. While persisting in pigs, the descendants of the 1918 virus have also been transmitted throughout the 20th century which resulted to the usual seasonal influenza outbreaks.
It is interesting to note that direct infection from pigs to humans is rare, with only 12 confirmed cases in the United States since 2005.

However, since the influenza strains remain in the pigs after they have disappeared in the human population can make these pigs a reservoir where the influenza virus could survive and later on transmitted to humans as soon as their immunity to the strain is no longe effective.

Swine flu has been recorded as zoonosis in humans several times, oftentimes with limited distribution and rarely with massive distribution. Swine outbreaks are common and can lead to significant economic losses in the industry, mainly leading to stunting and expanded market time. Swine influneza, for instance, the British meat industry has experienced 65 million of losses annually.

An Introduction To Swine Flu

Swine Flu-Is a respiratory track infection from the hogs. This kind of virus can kill the human race. This infection is a worldwide virus outbreak. A flu deadly disease occurs when a new influenza virus emerges for which people have little or no immunity and for which there is no vaccine. Those whom their hospitals are more than 10 miles from their community can easily infected with the Swine Flu.

The disease spreads easily person-to-person, and can be cause with serious illness, and can spread out across the country and even worldwide in a very short span of time. An influenza pandemic may be caused by either swine (pig) or avian (bird) flu viruses.

Swine flu viruses do not normally infect humans. But, randomly, the human race got infected with Swine flu. Most frequently, these cases occur in persons with direct exposure to pigs (example: owner and or workers in the swine backyard or industry or even the children near pigs at a fair).

Human-to-human transmission of Swine flu can also occur. This is thought to happen in the same way as seasonal flu occurs in people, which is mainly through coughing or sneezing of people infected with the influenza virus to an uninfected individual will be infected also. People may also become infected by touching something with flu viruses on it and then they touch their mouth or nose.

Some think that swine flu can also get from foods we eat. Take note that influenza viruses are not transmitted by food. You cannot get the influenza virus by means of eating pork or pork products. Eating properly handled and cooked pork is safe. Proper cooking of pork or pork products with an internal temperature of 160F will kill the swine flu virus as it does with other bacteria and viruses.

Fever, lethargy, lack of appetite, runny nose, sore throat, nausea, vomiting, diarrhea and coughing are some of the following symptoms of swine flu in people.

In diagnosing influenza infection, a respiratory specimen would generally need to be collected within the first 3 to 4 days of illness (when an infected person is most likely to be contagious). However, some persons, especially children, may be infectious for 10 days or longer.

If you get sick, there are two antiviral drugs (Tamiflu and Relenza) available with prescription can make your illness milder and make you feel better faster. They may also prevent serious influenza complications. In treatment, antiviral drugs work best if started as soon after getting sick as possible, and might not work if started more than 2 days after illness starts.

There are a number of things that you can do to prepare yourself and those around you for a flu pandemic. It is important to think about the challenges that you might face, particularly if an epidemic is rigorous.

The effects of a pandemic can be lessened if preparation is made ahead of time. Planning and preparation information and checklists are being prepared for various sectors of society, including information for individuals and families.

Different agencies are providing funding, advice, and other support from different rich nations to every country to assist with Swine Flu epidemic planning and preparation. Reading articles like this can help you plan against the spreading of the Swine Flu.

The Phases of Swine Flu

A process that happens if two different types of influenza virus infected a single cell and it can produce a new strain of influenza is called re-assortment. It will act as a “mixing vessel” in which re-assortment can occur between flu viruses of several species such as pigs are prone to influenza viruses that can also infect both humans and birds. This is because if the virus allows pieces of RNA from different viruses to mix together and form a novel type of virus as a new virus particles are being assembled from a virus splitting between eight independent pieces of RNA.

On the other hand, the World Health Organization raised the pandemic alert level from phase four to phase five, signaling that a pandemic is “imminent”.

To know more about different phases of Swine Flu as defined by the WHO, I enlisted six of them” defined by the WHO:

If a virus circulated among animals but there are no reported cases of infections to humans will fall under phase one. An example of this phase is an outbreak of flu symptoms in your hog race backyard.
In phase two there is an identified animal flu virus and caused infections to human, and it will be considered a potential pandemic threat.

An example is when the owner either the child or an adult within the hog race backyard got infected with a flu from their animal symptoms.
Phase 3 specified that a confirmed animal or human-animal flu virus has caused small outbreaks in human race, but has not resulted in human-to-human transmission that is sufficient to sustain community-level outbreaks. An example in this phase is when a child within the hog race backyard got infected together with his father, his mother and his siblings.

Radically in Phase 4, there is a cause of community-level outbreaks of human-to-human transmission of an animal or human-animal flu virus. This phase will focus to contain the spreading of the virus. The United Nations will then inform different countries asking to advice their people such as traveling to containment areas. All countries with infected with the swine flu must also consider in deploying a pandemic vaccine. An example of this when the infected family member went out from their backyard decided to talk to his friends and unaware that hes spreading the virus.

In the 5th phase, if there are at least two countries in one region and spread the virus by means of human-to-human transmission. The signal of the pandemic is imminently strong. The infected countries are required to advise people with respiratory illnesses to stay home. There should be an advisory of suspension of classes. An example of this is when a man-infected virus either a family member or any of his friends travel to another neighboring country.

The sixth and final phase also called the pandemic phase. A pandemic phase is just like a spread of virus in phase 5 but extended at least one other country outside their geographic region. There must be an implementation of contingency plans of health systems in all levels. An example of this is when a man-infected virus travel to another continent.

Whatever phases of Swine Flu outbreak, we are experiencing in our country or geographic region we must prepare and prevent it to spread to lessen the death toll.

Tamiflu And Relenza Against Swine Flu

Newsbreak on the flash: A new strain of Swine Flu that has killed 149 and sickened nearly two thousand in Mexico has spread to the United States and is raising fears of a possible pandemic. Through this article you will learn more about the disease and why it is causing concern among health officials and inform the readers about the two suggested antiviral drugs by Centers for Disease Control and Prevention (CDC) to fight Swine Flu pandemics.

This prescription of antiviral medication that can be used to treat influenza infections between children and adults is called Tamiflu. If their symptoms have started within the last two days they are advice to start taking the Tamiflu. This antiviral medication can also be used to prevent children, teens and adults if they are exposed to the influenza virus.

Relenza (ruh-LENS-uh) is more active than the Tamiflu. This kind of medicine, aside from treatment of influenza they can also prevent the suspect to getting the flu again. While some antiviral medicines only protect against influenza A, Relenza is effective against both influenza A and B. This Relenza drug belongs to neuramidase inhibitors group of medicines. These medications target the influenza virus and prevent it from spreading inside your body.

Relenza treats the cause of influenza at its source, rather than simply treating the symptoms like the role of Tamiflu. Simulations suggest that if physicians choose a second effective antiviral such as zanamivir. Zanamivir is the generic name of Relenza as first-line treatment in even a few percent of cases, but can solve to delay the spread of resistant strains.

The available antiviral treatments for influenza, the virus is resistant to rimantadine and amantadine, but sensitive to the oseltamivir and zanamivir. Oseltamivir is the generic name Tamiflu. This strain may mutate develop resistance of oseltamivir in the future.

Tamiflu and Relenza is highly recommended by the CDC for both treatment and prevention of the new strain. The shelf life of federally stockpiled Tamiflu from the original five years to seven years because studies indicated that the medication continues to maintain its effectiveness had already extended by the United States government and Roche Applied Science. Not only that, the other members of the G8 Countries extended their contract stockpiled of Tamiflu from vaccine manufacturers.

It is highly recommended not to buy from online pharmacies without an address of these two types of medications because their stockpiled are counterfeited. Consult to the World Health Organization for information about the antiviral drugs before making any steps in your country.

Medical experts warned the public not to take the antiviral drugs if you are not ill. You only want to be safe but the worst thing is if you take any of this antiviral drugs may lead you to a virus developing drug resistance. They suggest that antiviral drug should be taken only to very sick people or an individual with low immune system.

From the undetermined source that only one out of three Americans would get Swine Flu vaccine or antiviral drugs. So, it means the vaccine manufacturers especially the manufacturers of Tamiflu and Relenza have no enough capability to do more drugs against the pandemics.

According to CDC, testing has found that the Swine Flu virus remains at risk to two common antiviral drugs, Tamiflu and Relenza.