An Overview of Swine Flu

Swine flu or influenza is a condition caused by strains of subtypes of Influenza A virus called H1N1, H1N2, H3N1, H3N2, and H3N3. These viruses are common in pigs located in midwestern United States, Canada, South America, Mexico, Mainland China, Japan, Taiwan, Europe, and other Eastern Asian countries.

Transmission of influenza virus from swine to humans is relatively uncommon and does not always result to human influenza but often leads to production of antibodies in the blood. When properly cooked, pig meat does not have the potential of passing the virus. Transmission that leads to human influenza is called zoonotic swine flu.

People who work with pigs, particularly those with direct exposure, are at greater risk of being infected with swine flu. Towards the middle of the 20th century, identification of influenza subtypes became likely paving the way for an accurate diagnosis of transmission to humans. Since then, 50 infections have been confirmed and recorded.

It is rare for these strains of swine flu to be transmitted from one human to another. In humans, the symptoms of swine flu are similar to common influenza as well as influenza-like illness such as chills, sore throat, fever, coughing, muscular pains, severe headache, and general discomfort.
The 2009 swine flu outbreak in humans was caused by a new strain of influenza A virus subtype H1N1 which have genes that closely resemble swine influenza. The root of this new strain is not known. According to the World Health Organization for Animal Health, this new strain has not been isolated in pigs. It is capable of human-to-human transmission and manifests the normal symptoms of influenza.

Swine can be infected with human influenza such as the case of the 1918 flu pandemic and the 2009 flu outbreak. Swine flu was first proposed as a disease associated with humans during the 1918 flu pandemic. During that time, pigs became simultaneously sick with humans.

Influenza virus as a cause of disease in pigs was first identified in 1930. For the next six decades, strains of swine influenza became almost exclusively H1N1. From 1997 to 2002, new strains of three varied subtypes and 5 different genotypes were identified as the cause of influenza among pigs in North America.

From 1997-1998, H3N2 strains developed. They included genes acquired through reassortment of human, avian, and swine viruses and have been a principal cause of wine influenza in North America. Reassortment between H1N1 and H3N2 resulted to the development of H1N2. In Canada, a strain of H4N6 resulted from the reassortment of avian and swine flu but was isolated on a single farm.

The H1N1 variant of swine flu is one of the descendants of the strain that brought about the 1918 flu pandemic. While persisting in pigs, the descendants of the 1918 virus have also been transmitted throughout the 20th century which resulted to the usual seasonal influenza outbreaks.
It is interesting to note that direct infection from pigs to humans is rare, with only 12 confirmed cases in the United States since 2005.

However, since the influenza strains remain in the pigs after they have disappeared in the human population can make these pigs a reservoir where the influenza virus could survive and later on transmitted to humans as soon as their immunity to the strain is no longe effective.

Swine flu has been recorded as zoonosis in humans several times, oftentimes with limited distribution and rarely with massive distribution. Swine outbreaks are common and can lead to significant economic losses in the industry, mainly leading to stunting and expanded market time. Swine influneza, for instance, the British meat industry has experienced 65 million of losses annually.

Swine Flu Thousand Cases

A pandemic second quarter of 2009 outbreak of influenza A (H1N1) virus is a new strain of influenza virus identified commonly referred to as Swine Flu confirmed cases topped almost 6,000 individuals, as Belgium became the latest European nation to be hit by the influenza A(H1N1) virus. World Health Organization (WHO) officials said the number of cases of influenza A(H1N1) stood at around 6,000 and nearly 7,000 in more than 30 countries, with more than 60 people having died from the disease.

Cases were first discovered in the U.S. and officials soon suspected a link between those incidents and an earlier outbreak of late-season flu cases in Mexico. In less than a week hundreds of suspected cases, some of them serious, were discovered in Mexico. Soon thereafter, the WHO along with the Centers for Disease Control and Prevention (CDC) expressed concern that the A(H1N1) could become a worldwide flu pandemic, and WHO then raised its pandemic disease alert level to “Phase 5” out of the six maximum, as a “signal that a pandemic is at about to happen level”.

More than three thousand cases of infections including three deaths was the recorded highest number of A(H1N1) by the United States compared to Mexico where only more than two thousand reported cases of infection including 60 deaths were confirmed. The WHO said 389 people were also confirmed with the virus and one person had died in Canada who happens to be with the 19-year-old Chinese career that brings in to China a spread out. Two other cases have been confirmed in Hong Kong. Authorities there said they had quarantined six people who traveled with the second case, a 24-year-old man, by plane from San Francisco. A further 45 people who sat near him on his journey had already left Hong Kong, they said.

China, in the meantime, stepped up the search for people who came into contact with the mainland’s two confirmed Swine Flu patients. A 30-year-old man was confirmed to have the virus in the southwestern city of Chengdu. He had been in the United States before his homecoming to China. Plane (Air Canada flight to Beijing) and train (for Shandong Province with 20 people on board) travelers with a 5 meter contact with a 19-year-old student (his surname is Lu: second confirmed victim) are being haunted by Chinese Authorities in Beijing and Eastern Shandong province.

Hes not feeling well, a couple of days after his arrival in Beijing but still continue to travel by train with a fever, sore throat and a headache. They believed that virus highlighted in China and Hong Kong could be a mix of bird and human flu which came together in pigs.

Belgium confirmed its first case of Swine Flu in a 28-year-old man who also had been in the United States. Jose Angel Cordova (Health Minister of Mexico) moved to reassure tourists, saying that the country’s beaches and resorts an important source of foreign income — were safe for visitors. “There’s no risk to tourists,” he said, noting that most of the flu cases detected in holiday hotspots like Cancun and Acapulco dated back nearly two weeks.

The Swine Flu outbreak was expected to cost Mexico’s economy of more than 2 billion dollars or about 0.3 percent of gross domestic product.

Recalling the 1976 Swine Flu Debacle

In the history of the United States, this is not the first time that the country is experiencing a swine flu outbreak. The first recorded incident of H1N1 infection in the US was recorded on January 27, 1976, when there was a small outbreak of mild respiratory illnesses took place at Fort Dix Army Base in New Jersey.

According to throat cultures obtained from sick soldiers, each of the patients were infected by “swine-like flu virus” which have been unknown to humans since 1930. It was believed that the same virus was also responsible for the worst flu pandemic in the United States in 1918-1919 which led to the death of half a million Americans.

To many people, the discovery of the 1976 was more of a debacle than a victory because after only 10 weeks of implementation, vaccination efforts came to a premature close as the program led to complications which were associated to the shots.

After the death of Private David Lewis after participating in a forced five-mile march the night before his demise, Dr. David Sencer and his colleagues attributed the death to strains of swine-like flu virus. Upon the advice of specialists across the United States, Dr. Sencer called on then President Gerald Ford to launch a nationwide mass inoculation.

President Ford and the US Congress heeded the call and in October implemented the $137-million National Inoculation Program. However, after only several days of implementation, there were reports that the vaccine being used for the program made the patients prone to Guillain-Barre Syndrome, a rare neurological disorder which results to temporary paralysis but could be risky.

Prior to its premature end in December 1976, the vaccine was administered to over 40 million Americans comprising almost 25% of the population. From the over 500 people who experienced Guillain-Barre Syndrome after vaccine administration, 25 people died. As a result, the Federal Government paid millions worth of damages to the families of the victims.

Meanwhile, the epidemic which some experts predicted would affect 50 to 60 million Americans during that time never happened. According to the Center for Disease Control, there were only 200 confirmed cases and one death.

It is understandable why the current H1N1 outbreak has been a source of anxiety for the public who recalls the 1976 event. It serves as a lesson for the government and health officials who needs to make a decision on the current swine flu in the days and weeks to come.

Dr. David Sencer, who is now retired and resides in Atlanta, believes that the 1976 debacle brought good things as well as bad. The belief that the 1918-19 flu epidemic resulted from swine-like virus partly contributed to the 1976 setback.

Although current studies have shown that the cause of the epidemic was bird flu, it did not ease the current anxiety prevailing in the public. The 1918-19 epidemic led to the death of 500,000 people in the United States and more than 50 million worldwide.

In Mexico, where the 2009 swine flu outbreak, originated, 22 people have died from the most recent outbreak. Government officials have been under fire for the way they have handled the situation. However, with such a mystery surrounding the threat, Dr. Peter Katona, who is an authority on infectious disease from UCLA, believes that people have failed to understand the challenges posed by such problem.