Tag: depression

Drugs to Fight Alzheimer’s

Although there is no known cure yet for Alzheimer’s disease, there are already a number of drugs available worldwide that can help slow down a patient’s cognitive deterioration. The main aim of these Alzheimer’s medications is to try and improve cognitive ability or the person’s capability to think, perceive, judge and recognize.

There are currently five drugs approved by the Food and Drug Administration (FDA) that can be used to treat Alzheimer’s. There is ongoing research done all the time to test the effectiveness of such medications since they do not serve as a cure-all for the disease.
These medications may not have the same effects on all patients that are suffering from Alzheimer’s. But such prescription drugs can have significant effects on some of the patients with Alzheimer’s disease and should be given consideration as a possible treatment.

The 5 FDA Approved Medications are:
Aricept
Cognex
Exelon
Razadyne
Namenda

The first four drugs listed above belong to a group of drugs known as Cholinesterase Inhibitors. They work by trying to delay the break down of a substance known as acetylcholine in the brain which helps in bridging communication between nerve cells and has an important role in a person’s memory.

Nameda on the other hand acts on another neurotransmitter called glutamate and shields the brain from then said substance which contributes to the death of brain cells in people with Alzheimer’s disease. This drug is more effective in treating moderate to severe forms of Alzheimer’s disease, improving the day to day life of the person with Alzheimer’s disease.

The most common side effects associated with the drug Nameda include dizziness, confusion, constipation, headache and skin rashes. Some patients may experience less common side effects such as tiredness, back pain, high blood pressure, insomnia, hallucinations, vomiting and occasional shortness of breath.

The drugs Aricept, Exelon and Razadyne are seen to be most effective in treating the early stages of Alzheimer’s disease. This group of prescription drugs has been shown to have some modest effect in slowing down the degeneration of a patient’s cognitive abilities.

These drugs can also help in trying to reduce certain behavioral problems usually exhibited by people suffering from Alzheimer’s. When these drugs are administered effectively on an Alzheimer’s patient, they can significantly improve one’s quality of life and more able to cope up with the disease.

Alzheimer’s patients taking these medications may experience some side effects which may not be the same for all patients. Common side effects observed in patients using the drug Aricept include nausea, vomiting, excessive tiredness, sleeping troubles and muscle cramps.

Less frequent observed side effects of the drug are headaches and dizziness with rare cases of patients suffering from anorexia, gastric or duodenal ulcers, gastro-intestinal hemorrhage, bladder overflow obstruction, liver damage, convulsions, heart problems and psychiatric disturbances while using Aricept as medication.

The usual side effects seen in using Exelon as treatment for Alzheimer’s are nausea, vomiting, weight loss, stomach upset and fatigue. Less usual side effects observed with the use of the said drug are abdominal pain, sweating, diarrhea, headaches, tremor, and psychiatric disturbances such as anxiety or depression with rare cases of patients experiencing gastro-intestinal bleeding.

The drug Cognex is used less frequently for Alzheimer’s treatment as it can cause serious liver damage to most patients. Other side effects of the drug include nausea and vomiting. Some patients may also experience some abdominal pain, sore muscles, headache, dizziness, rapid breathing, increased urination, insomnia, runny nose or mouth, swelling in legs and feet when taking Cognex. Some of the most severe side effects associated with using Cornex are liver damage, heart problems and seizures.

The common side effects often reported with the use of Razadyne are nausea, vomiting, appetite loss and weight loss. Less common are fatigue, dizziness, tremor, headaches, abdominal pain, urinary tract infection, blood in urine, runny nose. There are no serious side effects with this drug.

A Personal Experience with Acupuncture

Let’s follow Susan as she goes to her first acupuncture treatment. Susan is a little hesitant, thinking of many needles sticking out of her in funny places so that she can’t find a place to sit easily. Her friend Marie had recommended this acupuncture clinic as a possible help for Susan’s recent problems of sleeplessness and depression. Susan was very surprised that Marie had ever visited an acupuncture clinic, as Marie didn’t seem to be someone that would visit something this unusual. And anyway, Marie always seems so remarkably healthy, attending the gym on a regular basis and still having lots of energy to spare. Susan was surprised to find out that Marie had been going to this acupuncture clinic for more than three years. She was even more surprised to find out that the first visit was suggested by Marie’s doctor – her family physician. Susan had no idea that a regular doctor would recommend a visit to an acupuncture clinic.

It turns out that a few years ago Marie had very intense cramps, and after a discussion with her doctor, they decided acupuncture might help to reduce or eliminate these. After having that treatment, Marie had discovered that some people visit the acupuncture clinic periodically just to keep in good health. Marie really enjoyed the way she felt, and so continued with the periodic visits as a kind of “tune up,” as she called them.

Though this is Susan’s first treatment at the acupuncture clinic, it is her second visit. Her first visit was to sit with the acupuncture practitioner to take several vital signs and to have a long discussion about her symptoms. Susan explained that she was hoping to get relief from the sleeplessness and depression through the treatments at the acupuncture clinic. She was surprised at the number of questions that she hadn’t thought about. She hadn’t noticed if the sleeplessness was the same on every night, or if she got to sleep more easily on some nights. She hadn’t noticed if she easily returned to sleep if she was awakened once she was asleep. She hadn’t thought about whether the sleeplessness started after they turned off the central heat in the house, now that spring had come. There were so many questions about that. There were questions she had expected, like that her depression could be related to the fact that her best friend at work had left for a new job. There were also surprising questions about patterns that she noticed about any previous depressions that she might have had. Once all the questions had been answered, Susan was asked to return another day for her first treatment in order to obtain the most beneficial results.

Susan pulled into the parking lot, still a little nervous. The acupuncture practitioner was a very nice and calm woman, but still… Twenty minutes later, Susan was sitting in a comfortable chair with about 18 needles at various points on her arms and ears. She was very comfortable, and inserting the needles did not hurt at all. After sitting there for 15 minutes, the acupuncture practitioner came in, removed the needles, and that was it. Susan was amazed! A sequence of 6 treatments had been prescribed initially, and they agreed to revisit Susan’s symptoms when these were done. She was so happy it was so easy!

Alzheimer’s, not just an old man’s disease

Alzheimer’s disease, we’ve all hear of it but do we really understand the disease? According to statistics, there are about 350,000 new cases of Alzheimer’s disease diagnosed each year in the United States.

Doing the math, you could have more than 4.5 million Americans by the year 2050 that would be affected by the disease. A grimmer outlook indicates that by 2025, there will be 34 million people worldwide Alzheimers disease.

Let’s tackle the issue step by step. Alzheimer’s disease is a known brain disorder that is progressive and irreversible. It is still not known where and how the disorder develops in the human brain neither is there any sure fire cure for the disease. What is known by medical scientists is that the disease attacks slowly.

It takes its time, gnawing slowly at the victims’ minds stealing memories and causing deterioration of brain functions. Alzheimer’s is a disease that causes irreversible dementia and is always fatal.

It was German psychiatrist Dr. Alois Alzheimer who first identified the disease. At first he noted the disease’s symptoms as “amnestic writing disordear,” however when later studies were conducted Dr. Alzheimer found out that the symptoms were more than ordinary memory loss. It was far worse.

Dr. Alzheimer found the presence of neurofibrillary tangles and amyloid plaques in the brain. The good doctor presented his findings which were accepted by the medical community. And soon enough, by 1910 the name of the disease was accepted and became known as Alzheimer’s disease.

The most common early symptoms of the disease are confusion, being inattentive and have problems with orientation, personality changes, experiencing short-term memory loss, language difficulties and mood swings. Probably the most obvious and striking early symptom of Alzheimer’s is loss of short term memory.

At fist the victim will exhibits minor forgetfulness, but as the disease slowly progress he/she will start to forget a lot of things. However, older memories are oftentimes left untouched. Because of this, patients with Alzheimer’s will start to be less energetic and spontaneous. As the disease progress, they will have trouble learning new things and reacting on outside stimuli which gets them all confused and causes them to exercise poor judgment. This is considered Stage 1 of the disease.

At Stage 2 the patient will now need assistance in performing complicated tasks. Speech and understanding is evidently slower. At this stage, Alzheimer’s victims are already aware that they have the disease which causes a whole lot of problems like depression and restlessness.

At this point, only the distant past can be recalled and recent events are immediately forgotten. Patients will have difficulty telling time, date and where they are.

The final stage is of course the hardest, both for the patient and their family. At Stage 3 the patient will start to lose control of a lot of bodily functions like simple chewing and swallowing. He/she will start getting the needed nutrients through a tube. At Stage 3, the patient will no longer remember basically anyone.
They will lose bowel and bladder control and they will become vulnerable to third party infections and diseases like pneumonia.
Once the patient become bedridden, things will only get worse. Respiratory problems will become more terrible.

It is apparent that the patient will need constant care. At this point, the most one can do is to make sure that the patient stays as comfortable as possible. At the terminal stage, death is inevitable.

Alzheimer’s Disease

People tend to forget certain things because of work and other priorities. This is not uncommon because this does happen to everybody. However, when an individual tends to forget even the simplest things, there is already something definitely wrong. There is a chance that one has Alzheimer’s disease.

Alzheimer’s disease is a disorder in the brain. In time, the patient will gradually lose both the intellectual and social abilities making it difficult to do anything and even interact with others.

This disease commonly afflicts people above 65 years of age. There are currently 4.5 million Americans that are suffering from this disease. It is projected that this number will increase, as the more population will reach the retirement age.

There is no known cure yet for Alzheimer’s disease. The only thing medical science can do for now is simply delay the inevitable for those who have just been diagnosed with the disease.

Is Alzheimer’s disease the same as dementia? The answer is no. This is because dementia is a symptom, which is caused by a disorder such as Alzheimer’s disease.

There are many symptoms for this disease. It may begin with the person simply forgetting certain things. It is hard to tell at this point but when it gets worse such as not knowing how to get to the office or get home, then there is definitely a problem.

Some patients are known to forget how to do some simple mathematical computations or even find the right words when writing a letter. There are those who are also disoriented and find it difficult to do certain tasks and make simple decisions.

The worse of these symptoms is perhaps experiencing personality changes even in the presence of family members and close friends. There are times the person is happy and then this will just change for no reason at all.

A neurological scan is the best way to check if the patient has Alzheimer’s disease. If it is confirmed, the individual has this problem, the best way to treat it is through the use of medical prescribed drugs.

There are two namely memantine and cholinesterase inhibitors. Studies have shown these can slow down the process as scientists are still conducting research to finally find a cure for this disease.

Patients who are diagnosed with the disorder will probably live more for 8 more years. This will really depend on how strong the person is because some have lived for 3 while others have fought with it for more than 10 years.

How can family members help a loved one with this disease? The siblings can take turns watching over the patient. If this is not possible, this is the time that a caregiver must be hired to check on the patient. This specialist will usually stay in the home and make sure the person is safe.

Physical and mental exercises must be administered to keep the patient’s strength up and even help depression, which is another symptom commonly, associated with Alzheimer’s disease.

Whenever the people visit, it is best for each person to stay in the line of sight of the patient. It is best to speak slowly and even hold on to the individual, which is known to make the sufferer remember who he or she is talking to.