Tag: Celebrex

Living And Coping With Arthritis – How To Stay Active

Living And Coping With Arthritis – How To Stay Active And Independent
Richard Clement

Arthritis pain can be frustrating.Nagging and crippling
arthritis pain can continue day after day. How much happier
would you be if you could stop your arthritis pain right now and
feel great all day? Knowing the nature of the disease can really
bring you the right answers.

What is arthritis ?

Arthritis comprises over 100 different diseases and conditions.
The word arthritis means “joint inflammation”. When joints are
inflamed, it causes pain and usually also limits movement of the
joints that are affected. For many people, arthritis pain has a
large impact on their life. Arthritis is second only to heart
disease as a cause of work disability. Arthritis limits everyday
activities such as walking, dressing and bathing for more than
16 million Americans. Each year, arthritis results in 750,000
hospitalizations and 36 million outpatient visits. Arthritis is
not just an old person’s disease. Nearly two-thirds of people
with arthritis are younger than 65 years including nearly
300,000 children. Arthritis affects children and people of all
racial and ethnic groups but is more common among women and
older adults. The disease can affect different parts of the
body. Two of the most common forms are osteoarthritis and
rheumatoid arthritis.

Rheumatoid arthritis (RA) is an autoimmune disease in which the
joint lining becomes inflamed as part of the body’s immune
system activity. RA is one of the most serious and disabling
types, affecting mostly women. Rheumatoid arthritis is two to
three times more common in women than in men and generally
strikes between the ages of 20 and 50. Both sides of the body
are usually affected at the same time. Symptoms of RA differ
from person to person but can generally include:

Joint tenderness, warmth, and swelling.

Pain and stiffness lasting for more than 1 hour in the morning
or after a long rest.

Joint inflammation in the wrist and finger joints closest to
the hand .

Fatigue, an occasional fever, and a general sense of not
feeling well . Osteoarthritis (OA) is the most common form of
arthritis. It is a degenerative joint disease in which the
cartilage that covers the ends of bones in the joint
deteriorates, causing pain and loss of movement as bone begins
to rub against bone. OA commonly affects the joints of the
fingers, knees, hips, and spine. Osteoarthritis is more common
in older people because they have been using their joints
longer. Using the joints to do the same task over and over or
simply using them over time can make osteoarthritis worse.
Younger people can also get osteoarthritis. Athletes are at risk
because they use their joints so much. People who have jobs that
require the same movement over and over are also at risk.
Injuries to a joint increase the risk of arthritis in the joint
later on. Excess weight can accelerate arthritis in the knees,
hips and spine. The most common symptom of Osteoarthritis is
pain in the affected joint(s) after repetitive use. Joint pain
is usually worse later in the day. There can be swelling,
warmth, and creaking of the affected joints. Symptoms of OA may
greatly vary. Some patients can be debilitated by their
symptoms. On the other hand, others may have remarkably few
symptoms in spite of dramatic degeneration of the joints
apparent on x-rays. Symptoms also can be intermittent. These 2
forms have very different causes, risk factors, and effects on
the body, yet they often share a common symptom—persistent
joint pain.

What are the causes of arthritis ? Primary OA is mostly
related to aging. With aging, the water content of the cartilage
increases and the protein makeup of cartilage degenerates.
Repetitive use of the joints over the years irritates and
inflames the cartilage, causing joint pain and swelling.
Eventually, cartilage begins to degenerate by flaking or forming
tiny crevasses. Inflammation of the cartilage can also stimulate
new bone outgrowths (spurs) to form around the joints. Sometimes
osteoarthritis follows an injury to a joint. For example, a
young person might hurt his knee badly playing soccer. Then,
years after the knee has apparently healed, he might get
arthritis in his knee joint. RA is an autoimmune disease. This
means the body’s natural immune system does not operate as it
should; it attacks healthy joint tissue, initiating a process of
inflammation and joint damage. RA is a type of chronic arthritis
that occurs in joints on both sides of the body (such as hands,
wrists or knees). This symmetry helps distinguish RA from other
types of arthritis. Rheumatoid arthritis occurs most frequently
in the 30-50 age group, although can start at any age. It is
strongly associated with the HLA marker DR4 – hence Family
history is an important risk factor. The disease affects
Females:Males in a 4:1 ratio. Other conditions can also cause
arthritis. Some include:

Gout, in which crystals build up in the joints. It usually
affects the big toe.

Lupus , in which the body’s defense system can harm the
joints, the heart, the skin, the kidneys, and other organs.

Viral hepatitis ,in which an infection of the liver can cause
arthritis.

What can you do about it ?

Some people may worry that arthritis means they won’t be able to
work or take care of their children and their family. Others
think that you just have to accept things like arthritis. While
there is not yet a cure for arthritis, much can be done today to
reduce pain and boost joint function. Learning how to manage
pain over the long term is essential to maintaining a good
quality of life. There are things you can do to keep the damage
from getting worse. They might also make you feel better.Here
are some simple things to do:

Lose weight if you’re overweight

Exercise regularly for short periods. Going for a walk every
day will help, too.

Use canes and other special devices to protect your joints.

Avoid lifting heavy things.

Don’t pull on objects to move them-push them instead

Use heat or cold to reduce pain or stiffness.

The pain and disability that accompany arthritis can be
decreased through early diagnosis and appropriate management.So
if you have persistent symptoms lasting more than several days –
go see your doctor. The doctor will examine you and may take x
rays (pictures) of your bones or joints to decide if you have
arthritis and what kind you have.

After the doctor knows what kind of arthritis you have, he or
she will talk with you about the best way to treat it. The
doctor may give you a prescription for medicine that will help
with the pain, stiffness, and inflammation. The good news is
that now there is a way to stop your pain with a medication .
Celebrex is a nonsteroidal anti-inflammatory drug (NSAID),
specifically a COX-2 inhibitor, which relieves pain and swelling
(inflammation). It represents a huge breakthrough in the
treatment of pain, inflammation, and stiffness of arthritis.
Celebrex is believed to fight pain and inflammation by
inhibiting the effect of a natural enzyme called COX-2. Unlike
the older medications, however, it does not interfere with a
similar substance, called COX-1, which exerts a protective
effect on the lining of the stomach.Celebrex doesn’t cause the
stomach bleeding and ulcers that traditional nonsteroidal
anti-inflammatory drugs (NSAIDs) might.

You always can visit my site
http://www.e-drugstore.ws/arthritis.html to find all the
information about coping with arthritis burden.

About the author:
Richard Clement is an online publisher dedicated in helping
online users getting appropriate and effective medical care.
Visit my site
http://www.e-drugstore.ws/arthritis.html for more info.

Bextra and Vioxx — Tips for Arthritis Relief Without Them

Bextra and Vioxx — Tips for Arthritis Relief Without Them
Charles Essmeier

The recent withdrawal of Vioxx and Bextra from the marketplace, due to concerns over unwanted side effects, has many arthritis sufferers concerned. These drugs, which belong to a powerful class of non-steroidal anti-inflammatory drugs known as COX-2 inhibitors, are quite effective at fighting the pain and inflammation of arthritis. Unfortunately, they have been linked to increased risk of strokes and heart attacks. Their manufacturers have voluntarily withdrawn them from the market. There are still alternative medications available, such as Celebrex, and traditional medications, such as aspirin or ibuprofen. Aspirin and ibuprofen may not be suitable for everyone, as they can cause stomach discomfort in some people. While a good anti-inflammatory can certainly provide more comfort for arthritis pain, there are some non-medicinal steps that patients can take that may provide some relief from their pain.

  • Get plenty of rest. Your body works best when its well-rested, and its a well-known fact that most Americans fail to get the recommended seven to eight hours of sleep each night.
  • Exercise. Joints and muscles work best when theyre well toned, and that is true for arthritis sufferers as well as the public at large. Not all exercises will be appropriate, however. A patient with arthritic knees will probably not benefit from playing basketball or tennis. Low impact exercise like walking or water aerobics may help, however. Patients with arthritis are advised to discuss exercise options with their physician.
  • Watch your weight. Arthritic joints work best when they arent overly burdened. If you are overweight, you are making a bad situation worse by forcing your joints to work harder than they otherwise might. A loss of just a few pounds could make a huge difference, especially if you suffer from arthritic knees.

    • These tips are certainly not intended to be a substitute for medication, but with a chronic condition like arthritis, every little bit that you can do to ease the stress on your aching joints can provide a bit more relief. About the Author
    Copyright 2005 by Retro Marketing. Charles Essmeier is the owner of Retro Marketing, a firm devoted to informational Websites, including Bextra-Info.net, a site devoted to the withdrawn drug Bextra and StructuredSettlementHelp.com, a site devoted to structured settlements.

    Aleve, Vioxx, Celebrex, and Bextra: What You Need to Know

    Aleve, Vioxx, Celebrex, and Bextra: What You Need to Know About Arthritis Pain Medications
    R.L. Fielding

    Aleve, Vioxx, Celebrex and Bextra:What You Need To Know About Arthritis Pain MedicationsRecent controversy about the safety of pain medications for arthritis has left patients and health care professionals alike confused about which medications are safe to use. In fact, a recent survey by the Boston-based Rippe Lifestyle Institute indicated that many people with arthritis are suffering unnecessarily because they have stopped or reduced their use of pain relievers due to confusion about which drugs are considered safe.The survey also showed that now, more than ever, those with arthritis need to understand the benefits and possible side effects associated with all arthritis pain medications. In order to do so, people with arthritis, their caregivers and families must be familiar with recent news about the two types of drugs most commonly used to treat arthritis pain non-selective, non-steroidal anti-inflammatory drugs (NSAIDs), and another group of NSAIDs known as cyclooxygenase-2 (COX-2) specific inhibitors. COX-2 specific inhibitors vs. Other NSAIDsCOX-2 specific inhibitors are the newest members of the NSAID class of medications. Available by prescription only, they became widely used in recent years to reduce joint pain and swelling. COX-2 specific inhibitors work by selectively blocking, or inhibiting, one of the two enzymes associated with inflammation. Some experts think that this selective inhibition may be one reason for some of the negative side effects currently associated with COX-2 specific inhibitors.Non-selective NSAIDs were developed earlier than COX-2 specific inhibitors and have been widely used to relieve arthritis pain and inflammation for many years. Unlike COX-2 specific inhibitors, non-selective NSAIDs inhibit both major enzymes involved in the inflammatory process, COX-1 and COX-2. The non-selective NSAID category includes a number of different medications that are available in both prescription and over-the-counter (OTC) products.Timeline of EventsTo understand the current state of affairs, it is important to understand the sequence of events. The controversy started when a study published in the October 21, 2004, issue of the New England Journal of Medicine cited the COX-2 specific inhibitor, Vioxx as potentially causing major adverse events, including heart attack and stroke, among patients taking the drug. As a result, Merck (the drugs manufacturer) voluntarily withdrew Vioxx from the market. However, in the months following, the safety of the other available COX-2 specific inhibitors such as Celebrex and Bextra, as well as other arthritis pain medications in the non-steroidal anti-inflammatory (NSAID) class, were also called into question.Consequently, in February 2005, the US Food and Drug Administration (FDA) convened a special Advisory Committee, made up of members of the Arthritis and Drug Safety Advisory Committees, to review the cardiovascular safety of these arthritis pain medications.FDA Directive: Stronger Warning Labels for Some Pain MedicationsOn April 7, 2005, taking into account the recommendations of the Advisory Committee, the FDA issued the following directives: Bextra, a COX-2 specific inhibitor manufactured by Pfizer, was withdrawn from the market.All prescription NSAIDs must revise their labeling to include a black box warning that highlights the potential increased risk for cardiovascular (CV) events as well as the potentially life threatening gastrointestinal (GI) bleeding associated with these drugs. Celebrex, the only COX-2 specific inhibitor remaining on the US market, was included in this directive.All OTC NSAIDs (except aspirin) will be required to revise their labeling to include more specific information about the potential for GI and CV side effects, a stronger reminder to follow label instructions, as well as a warning about potential skin reactions.To further evaluate the potential for increased CV risk, the FDA also announced that all NSAIDs must conduct and submit to the FDA a comprehensive review and analysis of pertinent safety data from clinical trials. Aleve (naproxen sodium) is supported by clinical studies conducted to gain approval of naproxen as a prescription product and as OTC that do not provide any evidence of increased risk of cardiovascular events. Treatment Options: What Should Arthritis Patients Know?For some people who suffer from pain associated with arthritis, their symptoms can be managed with exercise, heat/cold therapy, joint protection, assistive devices, weight control, or in some severe cases, surgery. For others, medications are needed to help manage the symptoms associated with arthritis. When taken as directed OTC medications such as Aleve provide a safe and effective way to treat mild to moderate pain of minor arthritis. If patients have questions, they should consult their health care professional about which treatment option is most appropriate.Why Its Important to Treat ArthritisArthritis affects approximately 66 million Americans and is the nations leading cause of disability. There are over 100 different types of arthritis, and they all have different symptoms that vary in severity from person to person. The most common form of arthritis, osteoarthritis, is characterized by the breakdown of cartilage that causes the bones to rub together, resulting in pain, loss of movements and stiffness . Arthritis is usually a chronic condition. For more information on Aleve and naproxen, visit the Aleve website at www.aleve.com. For more information on arthritis pain relief, visit www.arthritis.org. About the Author
    R.L. Fielding writes on a number of subjects.

    5 Tips for Arthritis Pain Relief

    5 Tips for Arthritis Pain Relief
    John Mancini

    For millions of people through out the world arthritis pain is
    something that they live with everyday. Most of them are on some
    type of prescription drug regimen to control the pain. However,
    drugs alone are often times not enough to keep the arthritis
    pain at bay. Therefore, there are a growing number of people
    that are seeking alternative arthritis pain relief. If you have
    considered some non-traditional treatment methods, but are
    unsure of how they work, the following tips will help to answer
    your questions.

    1- There are multiple pain medications available for people who
    suffer from arthritis pain. They consist of over the counter
    remedies such as acetaminophen and ibuprofen to the stronger
    prescription drugs such as Vioxx and Celebrex. The problem with
    the stronger drugs is that they often come with undesirable or
    even dangerous side effects. While the over the counter
    alternatives are safer, they often need to have other remedies
    used as well to achieve arthritis pain relief.

    2- Exercise is a great option at your disposal when looking for
    natural alternatives for your arthritis pain relief. Walking is
    especially good; it is easy to do and does not put too much
    unneeded pressure on the joints. Other forms of exercises that
    are especially good for arthritis sufferers are balancing types
    of movements, such as Tia Chi and water walking. While these
    activities can help build muscle strength, they may cause some
    discomfort in the joints. If this happens, stop the exercise, if
    the pain persists more than a couple of days speak with your
    physician.

    3- Losing weight is another great way to find some relief from
    your arthritis pain. This is because it has been found that just
    ten extra pounds adds thirty pounds of stress to the knees.
    Therefore, losing extra weight will be very effective for
    arthritis pain relief.

    4- Researching and using any product that will make your daily
    life easier, will also indirectly help ease the pain associated
    with arthritis. For example, using a shower seat will allow you
    to shower without much of the pain that can result from extended
    period of time standing.

    5- Visit your physician when you first feel that you are having
    arthritis pain. Together, the both of you will be able to devise
    a treatment regimen that is right for you and for your
    particular situation. Be sure to keep in contact with your
    doctor, this is the only way to ensure that your treatment
    methods will change as the pain becomes stronger.

    About the author:
    John Mancini has been writing about Rheumatoid Arthritis online
    and offline for a long time. Visit http://arthritis-expert.net
    or     http://arthritis-central.com to read more about matters like
    osteoarthritis and arthritis treatment.