Swine Flu Vaccine Close To Reality According to Experts

Officials of the Federal government believe that the swine flu vaccine that would protect all Americans from future H1N1 outbreaks would be available by January or late November at the earliest.

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wever, countries outside the United States and other nations that manufacture vaccines would take several years to generate sufficient vaccines to meet global demands.

Although manufacturing of the vaccine is faster than it was a few years back, it may still not be enough to prevent death and illness if the dreaded virus begins to spread and becomes virulent, experts predict.

In the United States, the main obstacle despite long years of effort remains to be the 50-year old technology they use in manufacturing flu vaccines. The Federal government had invested time and billions of dollars shifting to a quicker and more reliable method.

One such procedure involves cultivating the vaccine viruses in vats of cells instead of hen’s eggs. There are several small companies that are developing new methods that would pave the way for the creation of large volumes of vaccines in a span of weeks.

Dr. Greg Poland, who is the head of the vaccine research program at the Mayo Clinic, admits that the cell-based cultivation technology is not yet available while the never technologies have not yet been proven to satisfy most experts.

In addition, government officials have also not yet decided on whether or not H1N1 is a potential risk that demands production of vaccine. However, they are implementing the initial steps. Andrin Oswald, Chief Executive of the Vaccine Division of Novartis, revealed that one possible problem would be the manufacture of vaccines for swine influenza could hamper the production of seasonal flu vaccines for the coming winter. The most likely thing to do is to compromise, according to Oswald.

However, Robin Robinson, who manages the Emergency Preparation Research Program of the Department of Health and Human Services, believes that majority of manufacturing efforts of vaccine makers would have been completed by June.

According to Dr. Robinson, if the manufacture of the H1N1 vaccine would commence after that, the first 50 million to 80 million would be ready by September.

Dr. Robinson continued by saying that the entire 600 million doses, which are sufficient to give the required two shots for every American would be available by January. Adding the immune stimulant adjuvant to the vaccine could greatly reduce the required dosage, paving the way for the availability of the doses by the latter part of November.

The vaccine industry in the country is now very much capable of responding to the outbreak than it was five years back, when there were only two vaccine manufacturers and encountered a severe shortage. At present, there are five manufacturers supplying vaccines to the domestic market. The vaccine industry, which is used to be the backwater of the pharmaceutical industry, is generating new investments, as a result of government subsidies and higher cost for vaccines.

Despite of this, a World Health Organization and International Federation of Pharmaceutical Manufacturers and Associations revealed that it would still require four more years of manufacturing to meet global demands for a vaccine that would provide protection against bird flu strain that has been the major concern of health officials over the last few years.

Finally, the Federal government is encouraging manufacturers to shift their production in the United States, since all except Sanofi Aventis is now importing swine flu vaccines.

Recalling the 1976 Swine Flu Debacle

In the history of the United States, this is not the first time that the country is experiencing a swine flu outbreak. The first recorded incident of H1N1 infection in the US was recorded on January 27, 1976, when there was a small outbreak of mild respiratory illnesses took place at Fort Dix Army Base in New Jersey.

According to throat cultures obtained from sick soldiers, each of the patients were infected by “swine-like flu virus” which have been unknown to humans since 1930. It was believed that the same virus was also responsible for the worst flu pandemic in the United States in 1918-1919 which led to the death of half a million Americans.

To many people, the discovery of the 1976 was more of a debacle than a victory because after only 10 weeks of implementation, vaccination efforts came to a premature close as the program led to complications which were associated to the shots.

After the death of Private David Lewis after participating in a forced five-mile march the night before his demise, Dr. David Sencer and his colleagues attributed the death to strains of swine-like flu virus. Upon the advice of specialists across the United States, Dr. Sencer called on then President Gerald Ford to launch a nationwide mass inoculation.

President Ford and the US Congress heeded the call and in October implemented the $137-million National Inoculation Program. However, after only several days of implementation, there were reports that the vaccine being used for the program made the patients prone to Guillain-Barre Syndrome, a rare neurological disorder which results to temporary paralysis but could be risky.

Prior to its premature end in December 1976, the vaccine was administered to over 40 million Americans comprising almost 25% of the population. From the over 500 people who experienced Guillain-Barre Syndrome after vaccine administration, 25 people died. As a result, the Federal Government paid millions worth of damages to the families of the victims.

Meanwhile, the epidemic which some experts predicted would affect 50 to 60 million Americans during that time never happened. According to the Center for Disease Control, there were only 200 confirmed cases and one death.

It is understandable why the current H1N1 outbreak has been a source of anxiety for the public who recalls the 1976 event. It serves as a lesson for the government and health officials who needs to make a decision on the current swine flu in the days and weeks to come.

Dr. David Sencer, who is now retired and resides in Atlanta, believes that the 1976 debacle brought good things as well as bad. The belief that the 1918-19 flu epidemic resulted from swine-like virus partly contributed to the 1976 setback.

Although current studies have shown that the cause of the epidemic was bird flu, it did not ease the current anxiety prevailing in the public. The 1918-19 epidemic led to the death of 500,000 people in the United States and more than 50 million worldwide.

In Mexico, where the 2009 swine flu outbreak, originated, 22 people have died from the most recent outbreak. Government officials have been under fire for the way they have handled the situation. However, with such a mystery surrounding the threat, Dr. Peter Katona, who is an authority on infectious disease from UCLA, believes that people have failed to understand the challenges posed by such problem.

How Serious Is Swine Flu?

The United Kingdom has become the latest country to confirm cases of the swine flu. At the same time, the World Health Organization has raised its alert level from 3 to 4. With 150 people already killed in Mexico, the WHO revealed that the influenza virus has the sustainability for human-to-human transmission and can cause community level outbreaks.

One can recall a similar outbreak known as bird flu which was more risky than H1N1 virus. According to Professor Neil Ferguson of the World Health Organization, H1N1 is nothing when compared to other similar outbreaks such as SARS or the 1918 Spanish flu.

According to the professor, the evidence is clear that the United Kingdom is headed for a swine influenza pandemic in the coming months. However, it would be difficult to determine the extent of the epidemic since this is usually the time of the year when flu is prominent in the United Kingdom.

It is likewise almost sure that if the H1N1 outbreak disappears in the coming weeks, there might still be an outbreak of the virus in the autumn. If the situation indeed transforms into an epidemic, then 30% – 40% of the general population might become susceptible to infection. Professor Ferguson believes that any outbreak might become longer since the summer season in the United Kingdom is fast approaching.

On the other hand, Sir Liam Donaldson, who is concurrent Chief Medical Officer for England, believes that this new strain of H1N1 virus is something which people has natural immunity and has not received any vaccination yet. For this reason, one becomes susceptible to infection and spread to other people.
However, there is no sufficient information about the virus yet and H1N1 is still a subject of studies by major laboratories in the world. Once there is sufficient information about the virus, only then can it be possible to make improved predictions about individuals who are at higher risk and likely to have serious complications.

At present, the situation in Mexico is creating confusion and it is hard to make a firm a conclusion about what is likely to happen. In any case, there is a need to be ready for any untoward incidents that may happen.

Professor John Oxford, meanwhile, believes that the H1N1 outbreak is not as alarming as the H5N1 bird flu virus. He believes that the country can provide the basic H1N1 immunity for the population. The outbreaks outside of Mexico have not resulted to deaths which is an indication that the virus is not that aggressive.

Aside from that, the summer months is fast approaching so it is less probable for the H1N1 virus to cause an outbreak as well. In any case, the United Kingdom has enough antiviral medicines to treat half of the population.

With this in mind, there is no cause for worry about the H1N1 virus, as it appears that it would cause an outbreak that would be felt all over the world and increase mortality rates.

The outbreak of H1N1 began in Mexico City and as of today has resulted to the death of 42 people and more than 800 confirmed cases of swine flu infection. Although it has now spread in 22 countries, it is believed that this new virus outbreak would not be result to a pandemic and is milder than similar virus infections.

An Introduction To Swine Flu

Swine Flu-Is a respiratory track infection from the hogs. This kind of virus can kill the human race. This infection is a worldwide virus outbreak. A flu deadly disease occurs when a new influenza virus emerges for which people have little or no immunity and for which there is no vaccine. Those whom their hospitals are more than 10 miles from their community can easily infected with the Swine Flu.

The disease spreads easily person-to-person, and can be cause with serious illness, and can spread out across the country and even worldwide in a very short span of time. An influenza pandemic may be caused by either swine (pig) or avian (bird) flu viruses.

Swine flu viruses do not normally infect humans. But, randomly, the human race got infected with Swine flu. Most frequently, these cases occur in persons with direct exposure to pigs (example: owner and or workers in the swine backyard or industry or even the children near pigs at a fair).

Human-to-human transmission of Swine flu can also occur. This is thought to happen in the same way as seasonal flu occurs in people, which is mainly through coughing or sneezing of people infected with the influenza virus to an uninfected individual will be infected also. People may also become infected by touching something with flu viruses on it and then they touch their mouth or nose.

Some think that swine flu can also get from foods we eat. Take note that influenza viruses are not transmitted by food. You cannot get the influenza virus by means of eating pork or pork products. Eating properly handled and cooked pork is safe. Proper cooking of pork or pork products with an internal temperature of 160F will kill the swine flu virus as it does with other bacteria and viruses.

Fever, lethargy, lack of appetite, runny nose, sore throat, nausea, vomiting, diarrhea and coughing are some of the following symptoms of swine flu in people.

In diagnosing influenza infection, a respiratory specimen would generally need to be collected within the first 3 to 4 days of illness (when an infected person is most likely to be contagious). However, some persons, especially children, may be infectious for 10 days or longer.

If you get sick, there are two antiviral drugs (Tamiflu and Relenza) available with prescription can make your illness milder and make you feel better faster. They may also prevent serious influenza complications. In treatment, antiviral drugs work best if started as soon after getting sick as possible, and might not work if started more than 2 days after illness starts.

There are a number of things that you can do to prepare yourself and those around you for a flu pandemic. It is important to think about the challenges that you might face, particularly if an epidemic is rigorous.

The effects of a pandemic can be lessened if preparation is made ahead of time. Planning and preparation information and checklists are being prepared for various sectors of society, including information for individuals and families.

Different agencies are providing funding, advice, and other support from different rich nations to every country to assist with Swine Flu epidemic planning and preparation. Reading articles like this can help you plan against the spreading of the Swine Flu.