Scoliosis in Adolescents

Normally, a spine when viewed from rear should appear straight but if the spine is lateral or curved or sideways or rotated then it is affected by scoliosis. It gives an appearance as if the person has leaned to a side. According to Scoliosis Research Society the definition of scoliosis is the curving of the spine at an angle greater than 10 degrees on an x-ray. Scoliosis is a kind of spinal deformity and shouldnt be confused to poor posture. Usually there are 4 common kinds of patterns of curves experienced in Scoliosis which are: Thoracic wherein the right side has ninety percent curves, lumbar wherein left side has seventy percent curves, thoracolumbar wherein right side has eighty percent curves and double major where both right and left sides have curves.

In majority of the cases, as high as eight to eighty five percent, the cause of the deformity is unknown, this is also known as idiopathic scoliosis. It is observed that females have scoliosis more commonly than males. According to some established facts 3 to 5 children per 1000 has chances of developing spinal curves which is a number big enough requiring medical treatment. There are three types of scoliosis that can develop in children namely congenital, neuromuscular and idiopathic. Congenital scoliosis is seen in 1 out every 1,000 births which is caused due to vertebraes failure in normal formation, vertebrae is absent, vertebrae is formed partially and vertebrae is not separated. Neuromuscular scoliosis is linked with various neurological conditions and particularly in children who dont walk like cerebral palsy, muscular dystrophy, spina bifida, tumors in spinal cord, paralytic conditions and neurofibromatosis. The cause of third type of scoliosis called Idiopathic scoliosis is still unknown. It is further divided into infantile, juvenile and adolescent scoliosis. Infantile scoliosis occurs up to the age of 3 years from birth wherein the vertebrae curve is towards left and is more frequently observed in boys. The curve takes normal shape with the growth of child. Juvenile scoliosis is common in children of age three to nine. Adolescent scoliosis is common in kids of age ten to eighteen and this is also the most common form of scoliosis occurring more in girls than boys.

The other possible causes of the deformity include hereditary reasons, different lengths of legs, injuries, infections and tumors. There are numerous symptoms attributed to scoliosis which can vary from individual to individual. The symptoms are: Difference in heights of the shoulders, off-centered head, difference in the height or position of the hip, difference in the position or height of shoulder blade, different arm lengths in straight standing position and lastly different height back sides when the body is bent forward. Other symptoms include leg pain, back pain and change in bladder and bowel habits do not belong to the symptoms of idiopathic scoliosis and require medical checkup by a doctor. The symptoms may be similar to other problems related to spinal cord or other deformities or could result from an infection or injury and consulting a doctor is the best bet in this situation who may conduct diagnosis to know what exactly it is.

The diagnosis of scoliosis requires thorough medical history of the teenager, diagnostic tests and also physical examination. The doctor asks for entire prenatal history, birth history and also would want to know if anyone in the family has scoliosis. The doctor may also ask for the milestones related with the development of the teenager since some kinds of scoliosis are known to be related to neuromuscular disorders. The delay in development may need additional medical evaluation. Doctor may also prescribe x-ray, CT scan and MRI scan of the back to measure the degree of curvature in the spinal. There are various treatments available for scoliosis which is decided by the physician depending on teenagers age, medical history and health in general. The method of treatment also depends on the extent to which disease has reached. The tolerance of the teenager to certain medicines, therapies and procedures are also taken into consideration. Expectations and opinion of the parents or teenager is also the criteria in deciding the type of treatment. The main aim of the treatment is stop the curve from progressing and avert deformity. The treatments include observation and repetitive examinations, bracing and surgery to correct the defect.

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Drugs to Fight Alzheimer’s

Although there is no known cure yet for Alzheimer’s disease, there are already a number of drugs available worldwide that can help slow down a patient’s cognitive deterioration. The main aim of these Alzheimer’s medications is to try and improve cognitive ability or the person’s capability to think, perceive, judge and recognize.

There are currently five drugs approved by the Food and Drug Administration (FDA) that can be used to treat Alzheimer’s. There is ongoing research done all the time to test the effectiveness of such medications since they do not serve as a cure-all for the disease.
These medications may not have the same effects on all patients that are suffering from Alzheimer’s. But such prescription drugs can have significant effects on some of the patients with Alzheimer’s disease and should be given consideration as a possible treatment.

The 5 FDA Approved Medications are:
Aricept
Cognex
Exelon
Razadyne
Namenda

The first four drugs listed above belong to a group of drugs known as Cholinesterase Inhibitors. They work by trying to delay the break down of a substance known as acetylcholine in the brain which helps in bridging communication between nerve cells and has an important role in a person’s memory.

Nameda on the other hand acts on another neurotransmitter called glutamate and shields the brain from then said substance which contributes to the death of brain cells in people with Alzheimer’s disease. This drug is more effective in treating moderate to severe forms of Alzheimer’s disease, improving the day to day life of the person with Alzheimer’s disease.

The most common side effects associated with the drug Nameda include dizziness, confusion, constipation, headache and skin rashes. Some patients may experience less common side effects such as tiredness, back pain, high blood pressure, insomnia, hallucinations, vomiting and occasional shortness of breath.

The drugs Aricept, Exelon and Razadyne are seen to be most effective in treating the early stages of Alzheimer’s disease. This group of prescription drugs has been shown to have some modest effect in slowing down the degeneration of a patient’s cognitive abilities.

These drugs can also help in trying to reduce certain behavioral problems usually exhibited by people suffering from Alzheimer’s. When these drugs are administered effectively on an Alzheimer’s patient, they can significantly improve one’s quality of life and more able to cope up with the disease.

Alzheimer’s patients taking these medications may experience some side effects which may not be the same for all patients. Common side effects observed in patients using the drug Aricept include nausea, vomiting, excessive tiredness, sleeping troubles and muscle cramps.

Less frequent observed side effects of the drug are headaches and dizziness with rare cases of patients suffering from anorexia, gastric or duodenal ulcers, gastro-intestinal hemorrhage, bladder overflow obstruction, liver damage, convulsions, heart problems and psychiatric disturbances while using Aricept as medication.

The usual side effects seen in using Exelon as treatment for Alzheimer’s are nausea, vomiting, weight loss, stomach upset and fatigue. Less usual side effects observed with the use of the said drug are abdominal pain, sweating, diarrhea, headaches, tremor, and psychiatric disturbances such as anxiety or depression with rare cases of patients experiencing gastro-intestinal bleeding.

The drug Cognex is used less frequently for Alzheimer’s treatment as it can cause serious liver damage to most patients. Other side effects of the drug include nausea and vomiting. Some patients may also experience some abdominal pain, sore muscles, headache, dizziness, rapid breathing, increased urination, insomnia, runny nose or mouth, swelling in legs and feet when taking Cognex. Some of the most severe side effects associated with using Cornex are liver damage, heart problems and seizures.

The common side effects often reported with the use of Razadyne are nausea, vomiting, appetite loss and weight loss. Less common are fatigue, dizziness, tremor, headaches, abdominal pain, urinary tract infection, blood in urine, runny nose. There are no serious side effects with this drug.