The Relationship Of Gilbert’s Disease And Jaundice

Unpopular diseases such as Gilberts disease can be alarming once you are diagnosed with it because you will never know what will happen to you. Upon hearing that you are or you might be suffering from it, it can be hard to accept it because you dont know what to do.

To ease the burden that people with Gilberts disease, doctors try to explain everything about the condition in laymans terms. And one of the easiest ways to understand it is if it is compared to more common diseases that have similarities in it like jaundice.

What Gilberts disease is all about

Gilberts disease was first described by a French gastroenterologist names Augustin Nicolas Gilbert in 1901. Gilberts disease is an asymptomatic (no external symptoms) condition affecting the liver. The condition affect an enzyme in the body called urodine diphosphate glucuronosyltransferase or UGT (abbreviation). UGT aids the liver in breaking down bilirubin which is found also in the blood stream.

Bilirubin is the waste product of the hemoglobin in the blood. Hemoglobin is found in the red blood cells that carry oxygen to other cells in the body to complete the cycle of respiration. After the red blood cells successfully brought the oxygen to the other parts of the body, the blood produces bilirubin. The liver cells then collect all the bilirubin produced by the blood, transfer it to the liver to be broken down into the gut, and turned to bile.

This is where UGT or urodine diphosphate glucuronosyltransferase comes in, it helps the liver cells process the bilirubin in to bile. Gilberts disease affects the production of UGT, this is because it fluctuates the production of UGT in the body. The fluctuating levels of UGT greatly affect the levels of bilirubin retained in the blood. Bilirubin is orangey- yellow in color, which in turn causes a patient to have jaundiced skin.

What is jaundice?

Jaundice is the condition of the blood that has external manifestations. The two most common manifestation of Jaundice is the yellowing of the skin and in the white of the eyes. Jaundice if one of the most common symptoms or manifestations of different liver diseases and sometimes it may be the cause of some discomfort among patients. The heightened bilirubin stores in the body and in the bloodstream causes jaundice but it usually has no serious effects and it can occur in people more than once in their entire lifetime. Mild jaundice is not always caused by diseases of the liver there are times when it may happen under conditions of over exertion, long term stress, intense fasting, and other bodily infections, but the condition is otherwise shows no external manifestations.

It happens when there is a flaw in the liver that averts from removing bilirubin from the blood, to be converted to glucuronic acid (conjugated) or excreted in bile in this case if the person has Gilberts disease.

Lastly, when there is obstruction of the bile ducts that reduces the stream of bile and bilirubin from the liver into the guts. The decreased conjugation, emission, or gush of bile that can result in jaundice refers to cholestasis: however, cholestasis does not always effect in jaundice.

Jaundice or cholestasis, by themselves, causes just a few problems (excluding the conditions of newborns, and jaundice in this case in newborns is different from most other types of jaundice.) Jaundice can make the skin and the whites of the eyes look sclera yellow. As well, stool can turn out to be light in color, even clay-colored because of the lack of bilirubin that usually gives stool its brown color. The urine may become dark or brownish in color. This takes place when the bilirubin that is building up in the blood starts to be excreted from the body in the urine.

Other than those scenarios there is not much to worry about if you have Gilberts disease, you may experience a jaundiced appearance but you can still enjoy a healthy life.

Can You Get Spider Vein Treatment

Can you get spider vein treatment? That is one question that only your doctor can answer after conducting a thorough physical examination and reviewing your medical history.

The patients medical history is important because spider vein could be caused by age, heredity, medication or pregnancy. If you think that only females get it, men also do but it is rare for men to undergo treatment so this can be removed.

If you are considering spider vein treatment, you have to be physically fit because people who have circulatory problems, diabetes, heart condition or a blood born disease like hepatitis or AIDS cant undergo this procedure.

One issue that prevents some from undergoing spider vein treatment is the cost. It may be as low as $150 per leg but this could be much higher depending on how many veins have to be treated, how large are the veins, the experience of the doctor and where this will be done.

If you cant afford it, you may want to check if your insurance will be able to cover it. The bad news is that it is rarely covered by your provider because spider veins are considered to be a cosmetic problem, nothing else. If you are lucky, you will be required to present photographs or laboratory studies before your request is approved.

The procedure used by most doctors today is called sclerotherapy. Here, the doctor will inject needles into the affected veins. Studies have shown that the patients condition will improve by 50 to 90 percent but this takes months. The end result is that the spider veins will disappear but this does not prevent new ones from appearing later on.

Patients who choose to undergo sclerotherapy will be on an operating table for about 15 to 45 minutes. Again, this depends on how many veins need to be treated. Anesthesia is not used all throughout and you are awake the whole time. Since the needles are so thin, the only thing you will feel is a prick.

Once you have been injected with the fluid, the area will be bandaged and you will have to wear a prescribed tight fitting hose for 72 hours.

During this time, your legs will look like someone beat you up. To remove the sclerosing solution that was injected, your doctor will advise you to walk. Until the next session which is due in the following month, you should not carry heavy items, exercise, sit, stand or squat for a long period of time.

If money is not an issue and there is nothing in your medical history that is preventing you from undergoing sclerotherapy, the only thing you have to do now is look for a doctor.

Just be sure that the specialist is a member of the American Society of Plastic Surgeons (ASPS). These people are members of a bigger organization namely the American Board of Plastic Surgery (ABPS) and the Royal College of Physicians and Surgeons of Canada.

But can spider veins be prevented? Yes it can as long as you wear a support hose regularly as this helps prevent unwanted blood vessels from developing. You should also exercise regularly and maintain your weight. Lastly, you must avoid exposing yourself too much from the sun as its harmful rays can also do damage.

But some people still experience spider veins despite the measures mentioned and if you want to get rid of it, you have no choice but to undergo spider vein treatment.

Are There Side Effects for Spider Vein Treatment

Are there any side effects from spider vein treatment? There are a few but most people do not experience it. Just the same, you should know what could happen.

The first side effect is hyper pigmentation which occasional develops when the vein is injected. Fortunately, it does not that long and it normally fades. Since your skin will turn dark, one way to prevent people from seeing it is to wear pants or apply bleaching cream.

It is also possible that an inflammation will occur for a few days after the procedure. Doctors that perform on patients say that this is also normal because things will look worse before they get any better. You just have to bear with it.

Your skin may not turn dark but it can become reddish. This happens when multiple veins develop around the injection site.

The last spider vein treatment side effect is deep vein thrombosis. Of the four mentioned this is very rare and when it does happen, the patient will feel pain and the veins will be red, swollen and engorged.

If you experience any of these side effects, it is best to call your doctor immediately so he or she can come over and examine it further.

Doctors will always do their best to prevent complications and side effects like these from occurring. One of the things they do is let you answer a questionnaire and you have to answer it truthfully. You will also need to undergo a physical exam because you may or may not have spider veins but something more serious.

Patients who have circulatory problems, diabetes, heart condition or a blood born disease like hepatitis or AIDS are also not allowed because these people have the tendency to bleed or have poor healing.

If you experienced a blood clot in the past, the doctor will not say no right away so you still have a shot since this is decided on a case to case basis depending on the cause of the clot.

Women who are pregnant or are breast feeding are also not allowed to undergo this procedure because it could contaminate the milk which is fed to the infant and in some cases, spider veins go away on their own once the female gives birth. In both cases, the patient will just have to see the doctor later on if she still wants this done normally after three months.

You should avoid certain activities and taking certain things a week before surgery to prevent any problems. This includes not taking any medication especially antibiotics and not applying any lotion especially in the areas where the doctor will work on.

The side effects of spider vein treatment are minimal and in some cases very rare which is why sclerotherapy which was widely used in Europe has made its way to the US and doctors here have been performing this procedure for more than a decade.

You just have to find a licensed practitioner who will be able to perform this procedure safely so you can go out and show your legs. This could even make you look younger so you will feel good about yourself which is perhaps the best thing about this form of spider form treatment.

What You Should Know About Spider Vein Treatments

Spider veins are nothing more than a cosmetic problem. If you plan to undergo spider vein treatment, here are a few things you should know.

Before you undergo any type of treatment, you have to consult with your doctor. You will be asked a few questions with regards to your medical history, what medications you take, what type of work do you do and a few others because these are some of the cause of spider veins.

He or she will examine your leg to check if there are other problems. The hand held Doppler ultrasound device will be used to detect if there is a backflow within the venous system. If there are no serious problems, then you can undergo spider vein treatment but should there be any, you will be referred to another specialist.

Lets say there are no problems. Your doctor will then explain to you what happens when you undergo sclerotherapy. This procedure is the trend these days for this cosmetic problem. In this procedure, sclerosing agents are injected in the affected area which is designed to lighten the color of the veins.

If you have any questions, dont be afraid to raise them. Some people ask if it is going to hurt, what are the risks and benefits, how long is the recovery period and the costs which is perfectly normal since you will be the one who will undergo the procedure.

After getting all the necessary information and your willingness to still do it, you have to follow your doctors instructions to prepare you for treatment. You must not apply any moisturizer, sunblock or oil to your legs on the day of your procedure. You can wear shorts during the procedure but have to wear a prescribed support hose and slacks when you go home.

The procedure does not take that long. This may last from 15 to 45 minutes. It is a painless procedure and you dont have to be injected with anesthesia. If your doctor has their own clinic, it will be done right there.

Just how many injections will be used depends on the number of spider veins. Some patients will get 5 injections while this can go up to about 45. When the injection has been removed, the doctor will apply cotton ball and compression tape to that area of the leg.

Your legs will look bruised or slightly discolored for a few weeks and chances are you wont be going to the pool or beach for a few weeks because you will not be comfortable wearing a swimsuit. You can go to work and party but instead of wearing dress, you will be wearing slacks or a pair of jeans.

Since one session is not enough to make the spider veins unnoticeable, you will have to go back for the next session after one month. If new spider veins start appearing, it is your choice whether or not you want to undergo this procedure again. If you are vain, chances are you will.

Not everyone can undergo sclerotherapy. If you happen to suffer from diabetes, circulatory problems, heart condition or are suffering from a blood born disease like hepatitis or AIDS, you will have to find another form of spider vein treatment.