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Vaccinations of Swine Flu

Vaccine against seasonal influenza strain H1N1 is not believed to protect us. Vaccines against the Swine Flu to cope with seasonal flu to minimize infection rates are typically developed, and yet annually it still kills around half a million of the worlds population. Today, they use an injection of “killed virus”, the worlds flu vaccines. Manufacturers are asked to produce a vaccine for H1N1, they are unlikely to be able to respond quickly enough if a global pandemic is declared.

About a billion doses of any one vaccine each year is the only they can produce, so that even if all the capacity was switched to fight a pandemic flu, as opposed to a seasonal flu. Few years ago, the supply of the vaccines they have produced were enough to epidemic but now is not enough for the total populations outbreak.

Deadlier wave of a new H1N1 strain they forecast will reappear this fall and they have to produce pandemic vaccines as early as now to prepare for a turn out as the vaccine may not be as effective will be sure to a big waste of resources with serious results, and there would also be a shortage of seasonal flu vaccine available. Only a few more weeks were needed for the World Health Organization (WHO) and Centers for Disease Control and Prevention) CDC to develop a “seed strain” of the pandemic virus on the first days May, but producers would then need four to six months before they could create large volumes of vaccine.

In other point of view, the WHO will attempt to make sure that a substantial amount is available and should a pandemic be declared and a vaccine produced, for the benefit of developing countries. Vaccine manufacturers and countries with standing orders, such as the U.S. and some European countries will be asked to share with developing countries from the moment the first batches are ready if an H1N1 vaccine is made.

2009-2010 flu seasons are ineffective against the new strain with the previous influenza vaccines for the north and south hemispheres. The WHO claims that two separate immunizations will be required for seasonal and swine flu, but no decision would be made on whether to begin producing a swine flu vaccine. The board will receive inputs from manufacturers (e.g. GlaxoSmithKline, Sanofi-Aventis, Novartis and Baxter International) regarding when they are able to finish manufacturing the seasonal shot and begin production of the swine flu vaccine, waiting from the WHO of their recommendations and “seed virus”, and some may be ready to proceed with production at that time.

There also antiviral drugs available for treatments of influenza, the virus is resistant to amantadine and rimantadine but sensitive to the oseltamivir and zanamivir. There remains concern that this strain may mutate develop resistance to oseltamivir in the future. For the treatment and prevention of the Swine Flu, the CDC recommended the use of Tamiflu (oseltamivir) and Relenza (zanamivir). Studies shows that the medication continues to maintain its effective that why the U.S. government had already extended the shelf life of federally stockpiled Tamiflu from their original five years to seven years.

Buying medications from online sources is not recommended by the WHO because they believed that half of the drugs they sold are counterfeited. Others are thinking if they grab up antiviral drugs for their safe even if they have no symptoms, the health officials warned them may eventually lead them to the Swine Flu virus developing drug resistance.

The Phases of Swine Flu

A process that happens if two different types of influenza virus infected a single cell and it can produce a new strain of influenza is called re-assortment. It will act as a “mixing vessel” in which re-assortment can occur between flu viruses of several species such as pigs are prone to influenza viruses that can also infect both humans and birds. This is because if the virus allows pieces of RNA from different viruses to mix together and form a novel type of virus as a new virus particles are being assembled from a virus splitting between eight independent pieces of RNA.

On the other hand, the World Health Organization raised the pandemic alert level from phase four to phase five, signaling that a pandemic is “imminent”.

To know more about different phases of Swine Flu as defined by the WHO, I enlisted six of them” defined by the WHO:

If a virus circulated among animals but there are no reported cases of infections to humans will fall under phase one. An example of this phase is an outbreak of flu symptoms in your hog race backyard.
In phase two there is an identified animal flu virus and caused infections to human, and it will be considered a potential pandemic threat.

An example is when the owner either the child or an adult within the hog race backyard got infected with a flu from their animal symptoms.
Phase 3 specified that a confirmed animal or human-animal flu virus has caused small outbreaks in human race, but has not resulted in human-to-human transmission that is sufficient to sustain community-level outbreaks. An example in this phase is when a child within the hog race backyard got infected together with his father, his mother and his siblings.

Radically in Phase 4, there is a cause of community-level outbreaks of human-to-human transmission of an animal or human-animal flu virus. This phase will focus to contain the spreading of the virus. The United Nations will then inform different countries asking to advice their people such as traveling to containment areas. All countries with infected with the swine flu must also consider in deploying a pandemic vaccine. An example of this when the infected family member went out from their backyard decided to talk to his friends and unaware that hes spreading the virus.

In the 5th phase, if there are at least two countries in one region and spread the virus by means of human-to-human transmission. The signal of the pandemic is imminently strong. The infected countries are required to advise people with respiratory illnesses to stay home. There should be an advisory of suspension of classes. An example of this is when a man-infected virus either a family member or any of his friends travel to another neighboring country.

The sixth and final phase also called the pandemic phase. A pandemic phase is just like a spread of virus in phase 5 but extended at least one other country outside their geographic region. There must be an implementation of contingency plans of health systems in all levels. An example of this is when a man-infected virus travel to another continent.

Whatever phases of Swine Flu outbreak, we are experiencing in our country or geographic region we must prepare and prevent it to spread to lessen the death toll.

The Lowdown on The 2009 Swine Flu Outbreak

The 2009 outbreak of swine flu or H1N1 virus is recently hugging the limelight due to the potential harm or effects it can have on a patient or on a community. Unfortunately, the source of the virus still cannot be traced.

Before the first case in the United States was discovered, the illness was believed to have started in Mexico which eventually spread to other countries. Recently, the first case of swine flu was reported in
Costa Rica. Alarmed that it could grow into a worldwide flu epidemic, the World Health Organization of the United Nations and the Center for Disease Control Prevention (CDC) in the United States raised its pandemic alert level to Phase 5, which signifies that a “pandemic is imminent.”
While experts believed that the recent outbreak is not as fatal as previous epidemics, such as the SARS virus, health officials believe that the number of cases could go up as the new flu is expected to make its way throughout the United States.

The new swine influenza strain is apparently a new variant of four strains of influenza A virus subtype H1N1. According to the Center for Disease Control and Prevention, one of the strain is endemic in humans and birds and a couple are endemic in pigs.

However, according to scientists the 2009 H1N1 outbreak is of swine origin which is associated with the virus isolated in North America in 1998. To hasten understanding of the current outbreak as well as in coming up with a vaccine, scientists from Canada have completed the full genetic sequencing of the H1N1 virus.

The new strain of H1N1 has become widespread in Mexico and the United States with confirmed cases in 18 countries and suspected cases in 42 others. Travelers have been warned not to travel to affected countries such as Iceland, Singapore, Thailand, South Korea, Hong Kong, Singapore, to name a few.

In addition, warnings have also been issued warnings to visitors of countries affected by the outbreak. It is advisable for visitors to see the doctor right away if they experience flu-like symptoms.
In Mexico, schools, universities, and all public events were suspended from April 24 to May 6, 2009. In the United States, over 400 schools were closed as of May 3, 2009, which included schools in Texas and about 250,000 confirmed or probable cases.

Dr. Keiji Fukuda, who is the Assistant Director-General for Health Securiy and Environment of the World Health Organization confirmed that efforts to control the outbreak is already too late and should now focus on lessening the effects of the virus. He also clarified that closing borders or limiting travel to infected areas will do little in stopping the spread of the H1N1 virus.

On April 28, 2009, the Center for Disease Control and Prevention suggested that as much as possible, people should avoid non-important travel to Mexico.

According to Dr. Ira Longini, who is an expert in the mathematics and statistics of epidemics, staying at home, seeking medical care, closing public venues, and making anti-flu medicines accessible can help reduce the sickness by almost two-thirds.

Finally, according to Dr. Longini, the focus of efforts is to slow transmission until there is a vaccine that can be developed and made available for controlling swine flu outbreaks.

The Latest Killer Flu: Swine Flu And You

The Center for Disease Control has probably had some very wild times this past decade. First SARS, then the bird fle, and now today’s potential epidemic is the swine flu. First manifesting itself in Mexico this past April, this new and terrible strain of Type A H1N1 influenza is one of those things that every microbiologist and health care professional is afraid of.

The reason for that fear is pretty simple. Like the bird flu, this particular strain crossed species. Specifically, it crossed over from the swine population, a species that has an in-built resistance to it, to the human population, a population that does not. If this spreads and becomes a full blown epidemic, the swine flu may reach the heights of the 1918 Spanish Flu, which killed fifty to a hundred million people worldwide and devastated the post-World War I generation.

The CDC has stepped up its alert levels and some governments have instituted quarantine procedures, but still more and more cases are emerging across the world. Mexico City has most of the fatalities though, with most other cases outside of city being less severe in symptoms. However, this is just a month into the outbreak and anything can still happen. With the continuing spread of the disease, let’s talk about how this affects you.

Let’s be honest here, after all that I’ve just said, there’s actually no real reason to panic. Actually, we shouldn’t panic. That’s because panic just confuses people and to deal effectively with something of this magnitude, being confused is not the state of mind you want to be in. What you really need to be is to be aware and knowledgeable about what you’re dealing with. This and quick ddecisive action is what got the world through SARS and the bird flu, and it most likely will help us make sure that the swine flu isn’t the one that kills us all.

The swine flu is pretty much like your normal human flu. It has all the same infection vectors, all the same symptoms, and all the same treatments. It’s all just heightened by a factor of two, mostly because humans haven’t any natural resistance to the disease. If you want to avoid getting infected do all the same things that you’d do to avoid getting the flu: wash your hands regularly, take your vitamins, and avoid sick people.

If you somehow get sick, it’s not the time to run around like a headless chicken. You immediately isolate yourself so you won’t infect others and observe your symptoms, all of the while taking your regular flu medicine. Note that even if it is called swine flu, it’s still a virus and antiviral drugs are pretty effective in putting a dent in the symptoms you may experience and help your immune system kick the infection out.

It your symptoms persist despite your efforts, you better start calling for a doctor. Don’t worry if it really is the swine flu – the CDC has recommended the use of antiviral inhibitors that help stop the reproduction of the disease and the sickness is definitely treatable.

Let’s all just remember that the swine flu maybe deadly, but it’s still just a disease. And the only things you need to have to beat a disease is being smart and being careful. With all the noise that the media brings up about it, that fact may get lost in the shuffle. Remember it and it may just save your life.